1,344 research outputs found
It Is Not So Simply because an Expert Says It Is So: The Reliability of Gang Expert Testimony Regarding Membership in Criminal Street Gangs: Pushing the Limits of Texas Rule of Evidence 702.
The mechanisms developed by the criminal justice system addressing the criminal activities of street gangs, for the most part, have proved ineffective. The evolution of gangs, their complex structure, and multipurpose focus keep them one step ahead of law enforcement. The most recent weapon created to fight the war on gangs, the civil injunction, suffers from numerous inadequacies. One concern is that civil injunctions raise numerous constitutional concerns. Another is that these injunctions fall short of constitutional demands. Furthermore, the practical implementation of the injunction forces an analysis of the reliability of the gang expert’s testimony. This Article proposes courts exclude the testimony of a gang expert if there is no showing of substantial reliability. The opinions of gang experts regarding criminal street gangs, gang activities, and an individual’s membership in a gang are typically supported by more than the expert’s credentials. Gang experts are usually deemed qualified to give opinions regarding gangs because they have extensive training and have observed gangs and gang activities. Their testimony, however, is limited by the reliability of the data and the methods they use to collect that data. The criteria adopted by the State of Texas which determines gang membership—much like the criteria used in other jurisdictions across the nation—is notable for its circuitry and its potential for abuse, not its reliability. And although gang experts are generally experienced and trained, repeated observation of an event without inquiry, analysis, or experiment does not turn a mere observer into an expert. Accordingly, their testimony regarding gang membership does not meet the reliability requirements of Texas Rule of Evidence 702 and should be excluded
Property and the Role of Land-Based Cultural Heritage - Global and National - Welcome and Introduction.
Abstract Forthcoming
Risposta allo stress idrico di alcuni portainnesti del ciliegio allevati in ambiente controllato
Growth chamber estimation under severe water-stress of behaviour of 4 cherry rootstocks (seedling, Colt,
CAB/6 P and CAB/11 E) was carried out through the measure of leaf water potential, stomatal conductance
and transpiration rates.
This experience showed a positive correlation between leaf water potenti al and stomatal conductance, a
difference equivalent to 1,0 - 1,5 M Pa, O,5 - O,7 . sec→1 and 15/h/m2 of water respectively in leaf water potential,
stomatal conductance and transpiration rates between irrigated and stressed trees.
In particular, CAB/6 P selection resulted the most sensible to water stress, followed by CAB/11 E, Colt
and seedling; the last one kept more intense transpiration rates and showed more rapid restarting of stomatal
conductance during recovery than Colt
Materials recovery from WEEE: current situation in Sicily.
The potential recovery of materials and energy in one year in Italy and in Sicily was estimated assuming that all WEEEs were gathered through the collection – treatment – disposal system implemented according to the rules in force. The embodied energy (EE) recovery associated to material recovery was also estimated, starting from standard values of EE and from yields declared for each component. Mass fractions composition for some categories of WEEE given by a facility in Catania agree with the national averages. Starting from data given by another facility - located in Siracusa - which processes all the five R categories (R1 to R5), potential mass and energy recovery was estimated for this plant. The results compared with national estimates lead to the conclusion that currently this plant contributes by 6% as mass and by 5% for EE recovery. National figures for potential energy recovery from WEEE shows that 10 670 GWh could be theoretically recovered, that is as much as the energy used for civil needs in Italy by two millions people / yr
PTEN as a predictive marker of response to conservative treatment in endometrial hyperplasia and early endometrial cancer. A systematic review and meta-analysis
OBJECTIVE:
Several markers have been studied to predict the responsiveness of endometrial hyperplasia (EH) and early endometrial cancer (EEC) to progestin therapy. PTEN has played a major role in this field, although its predictive significance is still undefined. We aimed to assess if loss of PTEN expression on pre-treatment endometrial specimen may be a predictive markers of response to progestins in EH and EEC.
STUDY DESIGN:
MEDLINE, EMBASE, Web of Sciences, Scopus, ClinicalTrial.gov, OVID and Cochrane Library were searched for relevant articles from the inception to May 2018. All studies assessing PTEN expression as predictive marker in EH and EEC treated with progestin were included. Relative risk (RR) for therapy failure was calculated with 95% confidence interval (CI) and a significant p-value<0.05, with a subgroup analysis based on the histologic category (EEC or EH) and the administration route of progestin (oral or intrauterine).
RESULTS:
Seven cohort studies assessing 376 patients were included. PTEN loss was not significantly associated with the outcome of therapy in the overall analysis (RR = 1.24, 95% CI, 0.88-1.76, p = 0.21), in + the subgroups of EEC (RR = 0.89, 0.32-2.49, p = 0.83), EH (RR = 1.30, 0.90-1.87 p = 0.16), oral progestin (RR = 1.25 0.88-1.79, p = 0.22) and intrauterine device (RR = 1.02, 0.36-2.87, p = 0.97).
CONCLUSION:
PTEN seems not to be useful as predictive marker of response to the conservative treatment of EH and EC, regardless of the administration route (oral or intrauterine) of progestins. We advise future researcher not to further assess PTEN as a stand-alone predictive marker
Diabetes Mellitus Is Associated with Occult Cancer in Endometrial Hyperplasia
In the management of women diagnosed with endometrial hyperplasia (EH), it is crucial to determine the risk of coexistent cancer. Diabetes mellitus has been recently suggested as a significant risk factor. However, results in this regard are conflicting. Our aim was to assess the association between diabetes mellitus and coexistent cancer in women diagnosed with endometrial hyperplasia. A systematic review and meta-analysis was performed by searching electronic databases from their inception to October 2018 for studies assessing the presence of coexistent cancer after a preoperative diagnosis of endometrial hyperplasia in women stratified for diabetes mellitus. Odds ratio was calculated with 95% confidence interval; a p value <0.05 was considered significant. Twelve retrospective studies with 1579 EH were included. Diabetes mellitus showed significant association with the presence of cancer coexistent with endometrial hyperplasia (OR = 1.96; 95% CI, 1.07-3.60; p = 0.03). Heterogeneity among studies was moderate (I2 = 55%). Funnel plot showed asymmetric distribution of OR values, with the large and accurate studies showing results stronger than small and less accurate one; this finding should exclude a publication bias. In women diagnosed with endometrial hyperplasia, diabetes mellitus is a risk factor for coexistent cancer, and thus may be included in a predictive algorithm for the risk stratification. In women conservatively treated, glycemic control may be required to prevent the risk of progression. Further studies are necessary to confirm the clinical significance of diabetes mellitus in this field
Significant risk of occult cancer in complex non-atypical endometrial hyperplasia
BACKGROUND:
In the 2014 WHO classification of endometrial hyperplasia (EH), complex EH is lumped together with simple EH in the benign category of non-atypical EH.
OBJECTIVE:
To assess the risk of coexistent cancer in complex EH and simple EH without atypia, through a systematic review and meta-analysis.
METHODS:
Electronic databases were searched from their inception to January 2019 for relevant articles.
RESULTS:
Twelve studies assessing a total of 804 non-atypical EH were included. The risk of coexistent cancer was significantly higher in complex EH (12.4%) than in simple EH (2%), with an OR of 6.03 (p = 0.0002).
CONCLUSION:
Even in the absence of cytologic atypia, complex EH is associated with a significant risk of coexistent cancer. Further studies are necessary to investigate the need for a revision in the WHO classification
Draft Genome Sequences of Three Novel Staphylococcus arlettae Strains Isolated from a Disused Biological Safety Cabinet
The genome sequences of three new strains of Staphylococcus arlettae named Bari1, Bari2, and Bari3 are presented. The strains exhibited tolerance to hexavalent chromium ions. An sprC gene encoding a putative chromium transporter was present in each of the three draft genome sequences
- …