1 research outputs found
Apical Functionalization of Chiral Heterohelicenes
We describe a synthetic protocol to selectively functionalize
chiral
bridged triarylamines at the apical position using regioselective
copper-catalyzed amination reaction. This protocol allows the coupling
of diphenylamines with a sterically hindered but electronically activated
aryl–Br bond in the presence of a sterically unhindered but
electronically unactivated aryl–Br bond. The unactivated aryl–Br
bond was utilized further to synthesize a chiral heterohelicene homodimer
using Stille coupling