Thermal Modelling and Design of On-board DC-DC Power Converter using Finite Element Method

Power electronic converters are widely used and play a pivotal role in electronics area. The temperature causes around 54 % of all power converters failures. Thermal loads are nowadays one of the bottlenecks in the power system design and the cooling efficiency of a system is primarily determined by numerical modelling techniques. Therefore, thermal design through thermal modelling and simulation is becoming an integral part of the design process as less expensive compared to the experimental cut-and-try approach. Here the investigation is performed using finite element method-based modelling, and also the potential of such analysis was demonstrated by real-world measurements and comparison of obtained results. Thermal modelling was accomplished using finite element analysis software COMSOL and thermo-imaging camera was used to measure the thermal field distribution. Also, the improved configuration of power converter was proposed

A review and design of power electronics converters for fuel cell hybrid system applications

AbstractThis paper presents an overview of most promising power electronics topologies for a fuel cell hybrid power conversion system which can be utilized in many applications such as hybrid electrical vehicles (HEV), distributed generations (DG) and uninterruptible-power-supply (UPS) systems. Then, a multiple-input power conversion system including a decoupled dual-input converter and a three-phase neutral-point-clamped (NPC) inverter is proposed. The system can operate in both stand-alone and grid-connected modes. Simulation and experimental results are provided to show the feasibility of the proposed system and the effectiveness of the control methods

Investigation of Heat Sink Efficiency for Electronic Component Cooling Applications

Research and optimisation of cooling of electronic components using heat sinks becomes increasingly important in modern industry. Numerical methods with experimental realworld verification are the main tools to evaluate efficiency of heat sinks or heat sink systems. Here the investigation of relatively simple heat sink application is performed using modelling based on finite element method, and also the potential of such analysis was demonstrated by realworld measurements and comparing obtained results. Thermal modelling was accomplished using finite element analysis software COMSOL and thermo-imaging camera was used to measure the thermal field distribution. Ideas for future research involving improvement of the experimental setup and modelling verification are given

A novel de novo HDAC8 missense mutation causing Cornelia de Lange syndrome

Background: Cornelia de Lange syndrome (CdLS) is a rare and clinically variable syndrome characterized by growth impairment, multi-organ anomalies, and a typical set of facial dysmorphisms. Here we describe a 2-year-old female child harboring a novel de novo missense variant in HDAC8, whose phenotypical score, according to the recent consensus on CdLS clinical diagnostic criteria, allowed the diagnosis of a non-classic CdLS. Methods: Clinical exome sequencing was performed on the trio, identifying a de novo heterozygous variant in HDAC8 (NM_018486; c. 356C>G p.Thr119Arg). Molecular modeling was performed to evaluate putative functional consequence of the HDAC8 protein. Results: The variant HDAC8 c.356C>G is classified as pathogenic following the ACMG (American College of Medical Genetics and Genomics)/AMP (Association for Molecular Pathology) guidelines. By molecular modeling, we confirmed the deleterious effect of this variant, since the amino acid change compromises the conformational flexibility of the HDAC8 loop required for optimal catalytic function. Conclusion: We described a novel Thr119Arg mutation in HDAC8 in a patient displaying the major phenotypic traits of the CdLS. Our results suggest that a modest change outside an active site is capable of triggering global structural changes that propagate through the protein scaffold to the catalytic site, creating de facto haploinsufficiency

Change of Electronic Structure Induced by Magnetic Transitions in CeBi

The temperature dependence of the electronic structure of CeBi arising from two types of antiferromagnetic transitions based on optical conductivity ($\sigma(\omega)$) was observed. The $\sigma(\omega)$ spectrum continuously and discontinuously changes at 25 and 11 K, respectively. Between these temperatures, two peaks in the spectrum rapidly shift to the opposite energy sides as the temperature changes. Through a comparison with the band calculation as well as with the theoretical $\sigma(\omega)$ spectrum, this peak shift was explained by the energy shift of the Bi $6p$ band due to the mixing effect between the Ce $4f \Gamma_8$ and Bi $6p$ states. The single-layer antiferromagnetic ($+-$) transition from the paramagnetic state was concluded to be of the second order. The marked changes in the $\sigma(\omega)$ spectrum at 11 K, however, indicated the change in the electronic structure was due to a first-order-like magnetic transition from a single-layer to a double-layer ($++--$) antiferromagnetic phase.Comment: 4 pages, to be published in J. Phys. Soc. Jpn. 73 Aug. (2004