36 research outputs found
Expression of extracellular matrix components and their receptors in the central nervous system during experimental Toxoplasma gondii and Trypanosoma cruzi infection
Clinical-epidemiological profile of children with schistosomal myeloradiculopathy attended at the Instituto Materno-Infantil de Pernambuco
Chagas' Disease and HIV Co-infection: Genotypic Characterization of the Trypanosoma cruzi Strain
Cuidador de pessoa com acidente vascular encefálico: necessidades, sentimentos e orientações recebidas
A human astrocytoma cell line is highly susceptible to infection with Trypanosoma cruzi
Anticorpos a Trypanosoma cruzi no lÃquido cefalorraqueano: pesquisa pelas reações de fixação do complemento e de imunofluorescência
Involvement of central nervous system in the schistosomiasis
The involvement of the central nervous system (CNS) by schistosomes may or may not determine clinical manifestations. When symptomatic, neuroschistosomiasis (NS) is one of the most severe presentations of schistosomal infection. Considering the symptomatic form, cerebral involvement is almost always due to Schistosoma japonicum and the spinal cord disease, caused by S. mansoni or S. haematobium. Available evidence suggests that NS depends basically on the presence of parasite eggs in the nervous tissue and on the host immune response. The patients with cerebral NS usually have the clinical manifestations of increased intracranial pressure associated with focal neurological signs; and those with schistosomal myeloradiculopathy (SMR) present rapidly progressing symptoms of myelitis involving the lower cord, usually in association with the involvement of the cauda esquina roots. The diagnosis of cerebral NS is established by biopsy of the nervous tissue and SMR is usually diagnosed according to a clinical criterion. Antischistosomal drugs, corticosteroids and surgery are the resourses available for treating NS. The outcome is variable and is better in cerebral disease