1,871 research outputs found

    A Practical Case Study of the Interactive TV Service as a Time-Critical Product

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    In this paper, we conducted a case study of time-critical goods - NG goods. We expected the study to integrate the field of information management and the TV broadcasting field, thereby creating a new wave of potential for the information management field after e-commerce. We suggest two perspectives germane to industry development: the development of the whole industry, and, the operation of the individual companie

    Local Residents’ Risk Perceptions in Response to Shale Gas Exploitation: Evidence from China

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    In 2014, China became the world’s third country to accomplish shale gas commercial development, following the United States and Canada. China still however lacks a comprehensive analysis of its public’s concerns about potential environmental risks of shale gas exploration, particularly those of local residents near extraction sites. This paper specifically aims to explore risks perceived as associated with shale gas development in the Changning-Weiyuan area of Sichuan Basin, by conducting a face-to-face household survey with 730 participants interviewed. Some 86% of respondents reported their belief that shale gas exploitation causes more than three types of negative impacts, the most commonly perceived being noise, underground water contamination and geological disruption. Associated variables that were statistically significant predictors of risk perception include demographic characteristics (age, gender, education), environmental awareness level, landslide experience, awareness of past shale gas accidents, information sources, general knowledge about shale gas, and perspectives on whether negative impacts can be observed and controlled, along with trust in the central government and the petroleum company. Our findings implications are discussed, with the goal of informing both central and local authorities’ policy development in protecting local residents from risks of shale gas exploitation and better communicating risks to residents

    Northern Hemisphere Urban Heat Stress and Associated Labor Hour Hazard from ERA5 Reanalysis

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    Increasing surface air temperature is a fundamental characteristic of a warming world. Rising temperatures have potential impacts on human health through heat stress. One heat stress metric is the wet-bulb globe temperature, which takes into consideration the effects of radiation, humidity, and wind speed. It also has broad health and environmental implications. This study presents wet-bulb globe temperatures calculated from the fifth-generation European Centre for Medium-Range Weather Forecasts atmospheric reanalysis and combines it with health guidelines to assess heat stress variability and the potential for reduction in labor hours over the past decade on both the continental and urban scale. Compared to 2010–2014, there was a general increase in heat stress during the period from 2015 to 2019 throughout the northern hemisphere, with the largest warming found in tropical regions, especially in the northern part of the Indian Peninsula. On the urban scale, our results suggest that heat stress might have led to a reduction in labor hours by up to ~20% in some Asian cities subject to work–rest regulations. Extremes in heat stress can be explained by changes in radiation and circulation. The resultant threat is highest in developing countries in tropical areas where workers often have limited legal protection and healthcare. The effect of heat stress exposure is therefore a collective challenge with environmental, economic, and social implications.publishedVersio

    The Involvement of Neuron-Specific Factors in Dendritic Spinogenesis: Molecular Regulation and Association with Neurological Disorders

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    Dendritic spines are the location of excitatory synapses in the mammalian nervous system and are neuron-specific subcellular structures essential for neural circuitry and function. Dendritic spine morphology is determined by the F-actin cytoskeleton. Factin remodeling must coordinate with different stages of dendritic spinogenesis, starting from dendritic filopodia formation to the filopodia-spines transition and dendritic spine maturation and maintenance. Hundreds of genes, including F-actin cytoskeleton regulators, membrane proteins, adaptor proteins, and signaling molecules, are known to be involved in regulating synapse formation. Many of these genes are not neuron-specific, but how they specifically control dendritic spine formation in neurons is an intriguing question. Here, we summarize how ubiquitously expressed genes, including syndecan-2, NF1 (encoding neurofibromin protein), VCP, and CASK, and the neuron-specific gene CTTNBP2 coordinate with neurotransmission, transsynaptic signaling, and cytoskeleton rearrangement to control dendritic filopodia formation, filopodia-spines transition, and dendritic spine maturation and maintenance. The aforementioned genes have been associated with neurological disorders, such as autism spectrum disorders (ASDs), mental retardation, learning difficulty, and frontotemporal dementia. We also summarize the corresponding disorders in this report
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