Dama Gazelle (Nanger dama) conservation strategy 2019-2028

Produced following the workshop hosted by Al Ain Zoo in Al Ain, United Arab Emirates, 11-13 December 2018. Compiled and edited by: David Mallon, Lisa Banfield, Helen Senn & Hessa Al Qahtani.Peer reviewe

ASSESSMENT OF INTERSTITIAL LUNG MACROPHAGE PARTICLE BURDEN BY ANALYTICAL TRANSMISSION ELECTRON MICROSCOPE

Vingt biopsies pulmonaires transbronchiques réalisées au cours du bilan de pneumopathies diverses ont été étudiées en microscopie électronique à transmission analytique. La charge particulaire des macrophages interstitiels a été étudiée comme moyen d'évaluation des expositions antérieures aux particules inhalées.Transbronchial lung biopsies performed among 20 patients with various lung diseases were examined by means of an analytical transmission electron microscope. The particle burden of interstitial macrophages was studied for assessing exposures to inhaled airborne particles. Many interstitial lung diseases are related to the inhalation of mineral dusts and fumes in occupational and environmental settings. There is an increasing evidence that the study of biological specimens is very helpful for the assessment of human exposure to environmental pollutants. The analytical transmission electron microscope seems to be a very reliable method to obtain, on the same sample, both ultrastructural and analytical data on particles observed in situ. In this study the particle burden of transbronchial lung biopsies (TBLB) was investigated for assessing exposures to inhaled airborne particles