Characteristics of the study population.

<p>SD, standard deviation</p><p>Characteristics of the study population.</p

Association of MTI parameters of cortical gray matter and white matter with chronological age.

<p>Values represent standardized Betas. P-values (p) are adjusted for sex and affiliation to the offspring or control group.</p><p>MTR, magnetization transfer ratio</p><p>Association of MTI parameters of cortical gray matter and white matter with chronological age.</p

Association of MTI parameters of subcortical gray matter structures with chronological age.

<p>Values represent standardized Betas. P-values (p) are adjusted for sex and affiliation to the offspring or control group.</p><p>MTR, magnetization transfer ratio</p><p>Association of MTI parameters of subcortical gray matter structures with chronological age.</p

Voxel-based assessment of age-related changes of white matter magnetization transfer ratio (MTR).

<p>Fig. 1 shows results from the voxel-based assessment of age-related changes of white matter magnetization transfer ratio (MTR) in the whole study population using FSL-TBSS. Results are projected on the mean fractional anisotropy (FA) image of the whole study population which is derived from a diffusion tensor imaging (DTI) scan sequence. The mean white matter skeleton of the whole study population is shown in green color. Red color shows areas of statistically significant decrease of white matter MTR with increasing chronological age (p < 0.05).</p

MTI parameters of cortical and subcortical gray matter and white matter in offspring and control subjects.

<p>Values represent means (SE; standard error). P-values (p) are adjusted for age and sex and corrected for family relationships among the offspring.</p><p>MTR, magnetization transfer ratio</p><p>MTI parameters of cortical and subcortical gray matter and white matter in offspring and control subjects.</p