Twee gevallen van persisterende ductus arteriosus bij de hond

Patent ductus arteriosus (PDA) is one of the most common congenital heart disorders in dogs. If the condition is not corrected, more than half of the affected dogs die within their first year of life. Closure of the PDA by occlusion or ligation is therefore recommended and has a good long-term prognosis. The main complication of the non-invasive techniques is embolism, whereas bleeding after rupture of the ductus or an adjacent blood vessel is the most common problem with ligation. Two cases of PDA are discussed. In the first dog, the PDA was successfully corrected surgically. In the second case, however, serious bleeding occurred at several occasions during the surgery due to the exceptional presence of a persistent fifth aortic arch (PFAA). Intraoperative euthanasia was performed

Quadratic Unconstrained Binary Optimization for the Automotive Paint Shop Problem

The Binary Paint Shop Problem (BPSP) is a combinatorial optimization problem which draws inspiration from the automotive paint shop. Its binary nature, making it a good fit for Quadratic Unconstrained Binary Optimization (QUBO) solvers, has been well studied but its industrial applications are limited. In this paper, in order to expand the industrial applications, QUBO formulations for two generalizations of the BPSP, which are the Multi-Car Paint Shop Problem (MCPSP) and the Multi-Car Multi-Color Paint Shop Problem (MCMCPSP), are proposed. Given the multiple colors, the MCMCPSP is no longer natively binary which increases the problem size and introduces additional constraint factors in the QUBO formulation. Resulting QUBOs are solved using Scatter Search (SS). Furthermore, extensions of the SS that can exploit k-hot constrained structures within the formulations are proposed to compensate the additional complexity introduced by formulating non-binary problems into QUBO. Since no public benchmark database currently exists, random problem instances are generated. Viability of the proposed QUBO solving methods for the MCPSP and MCMCPSP, is highlighted through comparison with an integer-based Random Parallel Multi-start Tabu Search (RPMTS) and a greedy heuristic for the problems. The greedy heuristic has negligible computational requirements and therefore serves as a lower bound on the desired performance. The results for both problems show that better results can be obtained than the greedy heuristic and integer-based RPMTS, by using the novel k-hot extensions of the SS to solve the problems as QUBO

Reducing salt intake from meat products by combined use of lactate and diacetate salts without affecting microbial stability

In the framework of the trend towards lowering the salt content in meat products, an experiment was set up to determine combined effect of reducing the salt content with 20% or 40% and adding 2% or 3% Purasal((R)) Opti.Form PD 4 (a mixture of potassium lactate and sodium diacetate) on the shelf-life of a pre-packaged cooked meat product. By means of a challenge test with a mixture of two Lactobacillus sakei strains and a Leuconostoc mesenteroides strain, it was observed that use of lactate/diacetate mixture enabled a 40% reduction of the salt content in this cooked meat product, whereas the microbial shelf-life was significantly increased

Analyse van diergeneeskundige casussen /

Master of Veterinary Medicine in de diergeneeskunde: gezelschapsdiere