Community nurses’ support for patients with fibromyalgia who use cannabis to manage pain

Supporting patients to manage chronic pain conditions, such as fibromyalgia (FM), remains a challenge for community nurses. Research suggests that despite the absence of a licensed cannabis-based product for medicinal use (CBPM) available for people with FM in the UK, there is an appetite for FM patients to use cannabis for pain management. Nurses have expressed anxieties when balancing tensions between helping patients and working within medical guidelines, as well as a need for further education about patient cannabis use. This article provides community nurses with insight into how cannabis use affects the pain experience for people living with FM. Despite potential harms, cannabis is perceived by users to have a positive impact on the lived experience of pain, and it may be preferred to prescribed opioid medication. This understanding can help to inform empathic practice and recommendations are made for reducing the risks of cannabis use to patient health

Minimal Model for Disorder-induced Missing Moment of Inertia in Solid 4^4He

The absence of a missing moment inertia in clean solid $^4$He suggests that the minimal experimentally relevant model is one in which disorder induces superfluidity in a bosonic lattice. To this end, we explore the relevance of the disordered Bose-Hubbard model in this context. We posit that a clean array $^4$He atoms is a self-generated Mott insulator, that is, the $^4$He atoms constitute the lattice as well as the `charge carriers'. With this assumption, we are able to interpret the textbook defect-driven supersolids as excitations of either the lower or upper Hubbard bands. In the experiments at hand, disorder induces a closing of the Mott gap through the generation of mid-gap localized states at the chemical potential. Depending on the magnitude of the disorder, we find that the destruction of the Mott state takes place for $d+z>4$ either through a Bose glass phase (strong disorder) or through a direct transition to a superfluid (weak disorder). For $d+z<4$, disorder is always relevant. The critical value of the disorder that separates these two regimes is shown to be a function of the boson filling, interaction and the momentum cut off. We apply our work to the experimentally observed enhancement $^3$He impurities has on the onset temperature for the missing moment of inertia. We find quantitative agreement with experimental trends.Comment: 9 pages, 5 figures: Extended version of previous paper in which the pase diagram for the disordered Bose-Hubbard model is computed using mean-field theory and one-loop RG. The criterion for the Bose glass is derived explicitly. (a few typos are corrected

ARCS, The Arcminute Radio Cluster-lens Search - I. Selection Criteria and Initial Results

We present the results of an unbiased radio search for gravitational lensing events with image separations between 15 and 60 arcsec, which would be associated with clusters of galaxies with masses >10^{13-14}M_{\sun}. A parent population of 1023 extended radio sources stronger than 35 mJy with stellar optical identifications was selected using the FIRST radio catalogue at 1.4 GHz and the APM optical catalogue. The FIRST catalogue was then searched for companions to the parent sources stronger than 7 mJy and with separation in the range 15 to 60 arcsec. Higher resolution observations of the resulting 38 lens candidates were made with the VLA at 1.4 GHz and 5 GHz, and with MERLIN at 5 GHz in order to test the lens hypothesis in each case. None of our targets was found to be a gravitational lens system. These results provide the best current constraint on the lensing rate for this angular scale, but improved calculations of lensing rates from realistic simulations of the clustering of matter on the relevant scales are required before cosmologically significant constraints can be derived from this null result. We now have an efficient, tested observational strategy with which it will be possible to make an order-of-magnitude larger unbiased search in the near future.Comment: Accepted for publication in MNRAS. 12 pages, 29 included PostScript figure

Preconditioners for the spectral multigrid method

The systems of algebraic equations which arise from spectral discretizations of elliptic equations are full and direct solutions of them are rarely feasible. Iterative methods are an attractive alternative because Fourier transform techniques enable the discrete matrix-vector products to be computed with nearly the same efficiency as is possible for corresponding but sparse finite difference discretizations. For realistic Dirichlet problems preconditioning is essential for acceptable convergence rates. A brief description of Chebyshev spectral approximations and spectral multigrid methods for elliptic problems is given. A survey of preconditioners for Dirichlet problems based on second-order finite difference methods is made. New preconditioning techniques based on higher order finite differences and on the spectral matrix itself are presented. The preconditioners are analyzed in terms of their spectra and numerical examples are presented

Institutional Work as Logics Shift: The case of Intel's Transformation to Platform Leader

In this article, we explore some of the forms of institutional work that organizations perform as they participate externally in the processes that drive change in the institutional logic that characterizes their field, and as they respond internally to the shift as it occurs. More specifically, we present the results of an in-depth case study of Intel Corporation, a firm that was implicated in a fundamental shift in the institutional logic of its field in the late 1980s and 1990s as the field moved from a traditional supply chain logic dominated by computer assemblers to a new platform logic following very different organizing principles. Through the qualitative analysis of 72 interviews with Intel employees, complemented by extensive archival data from 1980 to 2000, we identify two forms of institutional work that Intel performed externally – external practice work and legitimacy work – and two forms of work that they carried out internally – internal practice work and identity work – as the organization worked to simultaneously influence the shift in logic that was occurring and to deal with the ramifications of the shift

Constraints On The Topology Of The Universe From The WMAP First-Year Sky Maps

We compute the covariance expected between the spherical harmonic coefficients $a_{\ell m}$ of the cosmic microwave temperature anisotropy if the universe had a compact topology. For fundamental cell size smaller than the distance to the decoupling surface, off-diagonal components carry more information than the diagonal components (the power spectrum). We use a maximum likelihood analysis to compare the Wilkinson Microwave Anisotropy Probe first-year data to models with a cubic topology. The data are compatible with finite flat topologies with fundamental domain $L > 1.2$ times the distance to the decoupling surface at 95% confidence. The WMAP data show reduced power at the quadrupole and octopole, but do not show the correlations expected for a compact topology and are indistinguishable from infinite models.Comment: 16 pages, 5 figure