249 research outputs found

    Walking the Walk: A Path to Support Open Access Publishing [Poster]

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    Scholarly communication is the lifeblood of universities. Threats to the free flow of research and ideas continue to jeopardize the entire academy; however administrators, scholars, and librarians are now pursuing options to reclaim research produced in the academy\u27s domain. One way to do this is with Open Access. Open Access has been a topic of interest and intense depabe for academic librarians. Ways to create awareness about and encourage publication in Open Access journals have been discussed at library conferences for the better part of the decade. But what is the next step? What happens when the library\u27s promotion pays off and teaching faculty seek support for their open access endeavors? This poster describes the steps taken to create a pilot program for an open access support fund at a Research I university. The program is one way to walk the walk of open access promotion by offering to subsidize costs associated with some open access publications. The poster includes practical information and tips such as: steps that can be taken to create a similar program; library and academic positions which may be involved; and opportunities and barriers that exist. Program documents, statistics and general impressions are provided

    Reduced Efficacy of Anti-A\u3cem\u3eβ\u3c/em\u3e Immunotherapy in a Mouse Model of Amyloid Deposition and Vascular Cognitive Impairment Comorbidity

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    Vascular cognitive impairment and dementia (VCID) is the second most common form of dementia behind Alzheimer\u27s disease (AD). It is estimated that 40% of AD patients also have some form of VCID. One promising therapeutic for AD is anti-Aβ immunotherapy, which uses antibodies against Aβ to clear it from the brain. While successful in clearing Aβ and improving cognition in mice, anti-Aβ immunotherapy failed to reach primary cognitive outcomes in several different clinical trials. We hypothesized that one potential reason the anti-Aβ immunotherapy clinical trials were unsuccessful was due to this high percentage of VCID comorbidity in the AD population. We used our unique model of VCID-amyloid comorbidity to test this hypothesis. We placed 9-month-old wild-type and APP/PS1 mice on either a control diet or a diet that induces hyperhomocysteinemia (HHcy). After being placed on the diet for 3 months, the mice then received intraperotineal injections of either IgG2a control or 3D6 for another 3 months. While we found that treatment of our comorbidity model with 3D6 resulted in decreased total Aβ levels, there was no cognitive benefit of the anti-Aβ immunotherapy in our AD/VCID mice. Further, microhemorrhages were increased by 3D6 in the APP/PS1/control but further increased in an additive fashion when 3D6 was administered to the APP/PS1/HHcy mice. This suggests that the use of anti-Aβ immunotherapy in patients with both AD and VCID would be ineffective on cognitive outcomes

    The Ursinus Weekly, April 28, 1978

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    Ursinus news in brief: Fire wakes New Dorm; Muds victorious; Faculty members promoted; Ec student cited; Files accessible; Weekly to change name; Hash bash • Richter outlines proposed changes • Judiciary Board revived • Reaction to Richter encouraging, optimistic • Comment: The Happy days • Letters to the editor: Necessary repair?; Fletcher controversy; Curriculum force in gear; And again; Student comments; Alumni speaks; Staff member reacts • Finally an answer: a modest proposal • Top tunes • Language action group: Dubious privilege • Cub and Key present alumni • Renaissance: Changing with the seasons • Apology • Women\u27s lacrosse cradles to Cape Cod • B-ball banquet • Muds win big • Lacrosse wrap-up • Ursinus track: 3-2 • Widener takes two • Tennis team optimistichttps://digitalcommons.ursinus.edu/weekly/1085/thumbnail.jp

    The Grizzly, September 29, 1978

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    Social changes open Fall term • Student Deans reorganized • Rebuck stresses individuality • News in brief: Lindback award presented to profs; Student dies suddenly; Miller heads Advance Ursinus; Women\u27s council meets; Fields speaks at VPI; Nine faculty appointed; Music director honored; New Alumni Secretary named • Ursinus middle class • Dr. Snyder, interim Dean • Letters to the editor: Damage policy questioned • Life on these American campuses • I. F. picnic: Let\u27s do it again • Good bands are available: Price shouldn\u27t be primary concern • Keith Moon: The life and death of The Who? • Richter welcomes frosh • USGA reports • Danforth fellowships offered • Portrait of the professor: Dr. Roger P. Staiger • Harriers open season • Football: Tough start • Sports profile: Dave Kennedy • Cross country looks strong • Football: Pre-season peek • Field hockeyhttps://digitalcommons.ursinus.edu/grizzlynews/1000/thumbnail.jp

    The Ursinus Weekly, October 21, 1977

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    Ursinus news in brief: Espada speaks at conference; Ursinus Homecoming; Buy a slave! • Craft elected as officer • New dining style proves popular • Board to vote on calendar • Students experience new dining style • Student employment remains stable • Comment: Student involvement; On cocktail grading • Letters to the editor • 1.2 million raised: Advance Ursinus first year • The Power behind Ursinus mediocrity • Homecoming candidates • Ursinus and the first digital computer • Bears finally come out of the woods • Varsity & JV hockey • C.C. 7-1! • 3 & 4: All wins • Volleyball: Dig it! • Bears winhttps://digitalcommons.ursinus.edu/weekly/1073/thumbnail.jp

    The Ursinus Weekly, December 2, 1976

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    Ursinus news in brief: Field hockey places second; Take \u27em to court?; McCarthy addresses Pre-Legal group; Forum Committee finalizes program • Alumni Directory published • Board plans tuition increase; Welcomes two new members • Career night planned • RPR addresses faculty • CR\u27s make a difference • Letters to the editor: More on Fritz ; A backside view of Wismer cafeteria • Comment: A tale of two students • Musical notes • Forum reviews: Tapestry, Mostovoys • Two gentlemen at Ursinus • Movie review: Network • Union board meets • Philly Co. • Bears 0-9 ... but the future looks brighter • Ursinus Equestrian Club news • Swim season opens • Phils not shoppinghttps://digitalcommons.ursinus.edu/weekly/1063/thumbnail.jp

    The Grizzly, October 20, 1978

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    Homecoming \u2778 Promises Color, Excitement • Judiciary Board Convicts Two • Shopping Center to Expand • On Personal Expression • Is Pledging All Fun and Games? • Ursinus\u27 Financial Aid Structure • SFARC Repairs Damage Policy • Gallagher Explores Amish • Springsteen & Dylan: Poet Laureates or Veritable Zeros? • The World\u27s Largest Hamburger • Paradise Lost: College Woods Gone Junkyard? • X-C: Dual Wins • Bears Fall Prey Again • Soccer Wins Five • News in Brief: Our New Look; Remember to Vote; Yom Kippur Celebration; Ursinus Announces Business Workshop; Library News Shortshttps://digitalcommons.ursinus.edu/grizzlynews/1003/thumbnail.jp

    The Grizzly, November 17, 1978

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    Tuition, Room And Board Fees Raised • GreaseBand Slated For January • Snow Precautions Outlined • Forum Highlights • Mail Theft In New Men\u27s • Hockey Violence Must Stop • Should Ursinus Teach Moral Values? • Acapulco: Gold • Rock\u27s Lesser-Knowns Provide Fresh Sound • Audio Corner: Purchasing audio equipment • Forum Committee • GM: Looking Good For \u2779 • A History Of Accomplishment • Bear Pack Bombs At Districts • Equestrians Riding High • Letters to the Editor: Public Apology; Grading Disputedhttps://digitalcommons.ursinus.edu/grizzlynews/1007/thumbnail.jp

    The Lantern Vol. 43, No. 1, Fall 1976

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    • Frustration • Think Again • My Sweet • Secret Society of One • November Ghosts • A Lonely Girl\u27s Prayer • Visions of You • The Innocence Baby • Society • Silence • Don\u27t Turn Around • Waves • Loneliness • Time Writer • Brood • It\u27s Not Funny • Four Haiku, Entwined • We\u27ll Have to Stop Meeting Like This • Castles In the Sand • The Seahttps://digitalcommons.ursinus.edu/lantern/1109/thumbnail.jp

    Characteristics of frequent emergency department presenters to an Australian emergency medicine network

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    <p>Abstract</p> <p>Background</p> <p>To describe the characteristics of emergency department (ED) patients defined as frequent presenters (FP) presenting to an Australian emergency department network and compare these with a cohort of non-frequent presenters (NFP).</p> <p>Method</p> <p>A retrospective chart review utilising an electronic emergency medicine patient medical record database was performed on patients presenting to Southern Health EDs from March 2009 to March 2010. Non-frequent presenters were defined as patients presenting less than 5 times and frequent presenters as presenting 8 or more times in the study period. Characteristics of both groups were described and compared.</p> <p>Results</p> <p>During the 12-month study period there were 540 FP patients with 4549 admissions and 73,089 NFP patients with 100,943 admissions. FP patients were slightly older with a significant increase in frequency of patients between the ages of 70 to 79 years and they were more likely to be divorced or separated than NFP patients. Frequent presenters to the emergency department were more likely to utilise the ambulance service to arrive at the hospital, or in the custody of police than NFP patients. FPs were more likely to be admitted to hospital, more likely to have an admission to a mental health bed than NFP patients and more likely to self-discharge from the emergency department while waiting for care.</p> <p>Conclusions</p> <p>There are major implications for the utilisation of limited ED resources by frequent presenters. By further understanding the characteristics of FP we may be able to address the specific health care needs of this population in more efficient and cost effective ways. Further research analysing the effectiveness of targeted multidisciplinary interventions aiming to reduce the frequency of ED attendances may be warranted.</p
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