15 research outputs found

    Survival Plots.

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    <p>Solid line: PRE period, dashed line: POST period.</p

    Single Classification Trees.

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    <p>Each node in the tree represents the splitting variable, as well as the splitting threshold for continuous variables.</p

    Permutation-Based Variance Importance Measure.

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    <p>The variables are ranked from the most important (top) to the least important (bottom). Variable importance is represented on the x-axis as the z-score. SAPS II: Simplified Acute Physiology Score II; ARDS: acute respiratory distress syndrome; Charlson: modified Charlson comorbidity index; ICU: intensive care unit.</p

    Disability and health-related quality-of-life 4 years after a severe traumatic brain injury: A structural equation modelling analysis

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    <p><i>Objectives</i>: To assess predictors and indicators of disability and quality-of-life 4 years after severe traumatic brain injury (TBI), using structural equation modelling (SEM).</p> <p><i>Methods</i>: The PariS-TBI study is a longitudinal multi-centre inception cohort study of 504 patients with severe TBI. Among 245 survivors, 147 patients were evaluated upon 4-year follow-up, and 85 completed the full assessment. Two outcome measures were analysed separately using SEM: the Glasgow Outcome Scale-extended (GOS-E), to measure disability, and the QOLIBRI, to assess quality-of-life. Four groups of variables were entered in the model: demographics; injury severity; mood and cognitive impairments; somatic impairments.</p> <p><i>Results</i>: The GOS-E was directly significantly related to mood and cognition, injury severity, and somatic impairments. Age and education had an indirect effect, mediated by mood/cognition or somatic deficiencies. In contrast, the only direct predictor of QOLIBRI was mood and cognition. Age and somatic impairments had an indirect influence on the QOLIBRI.</p> <p><i>Conclusion</i>: Although this study should be considered as explorative, it suggests that disability and quality-of-life were directly influenced by different factors. While disability appeared to result from an interaction of a wide range of factors, quality-of-life was solely directly related to psycho-cognitive factors.</p
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