Basic immunology teaching notes

These resources were created to assist teaching basic immunology to medical students. <div><br></div><div>The aim is to provide a memorable, visual representation of some of the major core topics in human immunology as a foundation for further learning. </div

Publishers, Papers and Peer Review: how we can improve academic data sharing and publishing

These are the supporting files for a meeting hosted in Oxford in January 2017, representing key stakeholders in academic publishing. <div><br><div>Discussions focused on publicising new platforms for data sharing, encouraging publication of diverse output (negative results, methods, datasets), challenging barriers to publication, and discussing improvements to the peer review process. </div><div><br></div><div>Please see the references section for other relevant supporting information. </div></div

Vaccine hesitancy - public engagement activity

These posters were created for public engagement events, aiming to engage a general audience in thinking about the use of vaccines in different scenarios. Participants are invited to discuss the scenarios and then indicate with a sticker where on each scale they place themselves. Over the course of the event visual data is thus collected that represents the overall views of the group. The results can be compared between different audiences and between different scenarios,  and can be used to inform further discussion about the use of vaccines and public health decision-making. </p

Malaria worksheet: a teaching resource for primary schools

This is a resource created for a workshop focusing on malaria infection aimed at primary school children (age 5-11 years). The idea is to provide stimulating material that inspires interest and intrigue, raising questions for discussion and encouraging children to get involved.<div> <div>We used the worksheet in parallel with an activity to 'act out' the transmission of malaria; we created our own mosquitoes from coloured paper and pipecleaners, set up a 'swamp' in the classroom, used red stickers to represent infection, and hung a mosquito net, sprayed ourselves with insect repellent, and talked about wearing the right kind of clothing to illustrate how we might protect ourselves. </div></div><div><br></div><div>The themes covered can be broad, from asking children to consider what we mean by a 'germ' or an 'infection', thinking about the different ways infection can be spread, discussing how we might be made vulnerable by where we live in the world and by changes in climate, and talking about ways that we can intervene to tackle disease and break transmission. </div

Viral Footprints - Dialysis Unit

Celebrating creativity in a dialysis uni

Shiny App - PARV4 prevalence, phylogeny, immunology and coinfection with HIV, HBV and HCV in a multicentre African cohort

This deposit provides an interactive treemap for exploring the PARV4 prevalence data made available here: https://doi.org/10.6084/m9.figshare.4707316<div><br></div><div>Martin John Hadley is the data visualisation developer, and Philippa Matthews is the principal investigator and lead author for both the dataset and publications this visualisation is linked to.</div

Summary table of monovalent hepatitis B vaccine preparations

This is a summary table of monovalent vaccines available for prevention of infection with hepatitis B virus (HBV), including information on manufacturer, storage conditions and stability, adjuvants and efficacy

hepitopes

<p>Hepitopes is a project to collate all the existing HBV epitopes restricted by HLA Class I genes, and to develop this into a live on-line resource that can grow and develop over time.</p><p>The initial stage of this work has been to perform a literature search to identify all epitopes that have been published to date. We have undertaken a detailed review of all the references such that we can list epitope HLA-restrictions, locations in the HBV proteome, sequences and polymorphisms, and report preliminary data regarding the potential clinical significance of epitope-specific T cell immune responses.</p><p>Over time, this database will continue to be updated such that we can develop and maintain an open-access resource that is useful for basic research and clinical vaccine design. This will include new epitopes identified as a result of my own work in Hepatitis B immunogenetics, as well as continuing to identify and collate new epitopes published by other groups.</p><a href="https://github.com/martinjhnhadley/hepitopes#data-and-license-details"></a>Data and License Details<table><tr><th></th><th></th></tr><tr><td>Data:</td><td><a href="https://dx.doi.org/10.6084/m9.figshare.4015824">https://dx.doi.org/10.6084/m9.figshare.4015824</a> (Live Data) <br><a href="https://dx.doi.org/10.5287/bodleian:zr0VAr78q">https://dx.doi.org/10.5287/bodleian:zr0VAr78q</a> (Deposit at time of publication)</td></tr><tr><td>Live Visualisation:</td><td><a href="http://www.expmedndm.ox.ac.uk/hepitopes">www.expmedndm.ox.ac.uk/hepitopes</a></td></tr><tr><td>Citing works:</td><td>Lumley S, Noble H, Hadley M et al. Hepitopes: literature review and database of HLA Class I epitopes in Hepatitis B Virus (HBV) [v1; not peer reviewed]. F1000Research 2016, 5:2357 (poster) (doi: <a href="http://dx.doi.org/10.7490/f1000research.1113165.1">10.7490/f1000research.1113165.1</a></td></tr><tr><td>License:</td><td>MIT</td></tr><tr><td>Copyright:</td><td>University of Oxford, 2016</td></tr><tr><td>Authors:</td><td>Lumley, Sheila <br><a href="http://orcid.org/0000-0001-5891-2932">Noble, Howard</a><br><a href="https://github.com/martinjhnhadley/hepitopes/blob/master/orcid.org/0000-0002-3039-6849">Hadley, Martin</a><br>Callow, Liz<br>Malik, Amna<br>Chua, Yi Yi<br>Duffey, Owen J<br>Grolmusova, Natalia<br>Kumar, Arvind<br>Ravenscroft, Samuel<br>Spencer, Jonathan I<br>Neumann-Haefelin, Christoph<br>Thimme, Robert<br>Andersson, Monique<br>Klenerman, Paul<br>Barnes, Eleanor<br><a href="http://orcid.org/0000-0002-4036-4269">Matthews, Philippa</a></td></tr></table

Viral Footprints - Hospital School

Celebrating creativity for young people in a hospita

Viral Footprints - Dialysis Unit - Day 4

A creative day in a dialysis unit with inspiration from viruses and and the immune system to spark conversation, interest, learning and reflection