6 research outputs found
Additional file 1: of Oral fosfomycin for treatment of urinary tract infection: a retrospective cohort study
Spreadsheet reporting 75 unique patients treated with fosfomycin for urinary tract infections. This excel file contains anonymised details of 75 unique adult patients treated with fosfomycin for urinary tract infections at Oxford University Hospitals NHS Foundation Trust from March 2013 through June 2015. Our original analysis also included patient sex, but this has been removed from the suppl. data file in order to protect anonymity. (XLSX 24Â kb
Additional file 2: of Oral fosfomycin for treatment of urinary tract infection: a retrospective cohort study
Tabulated summary of studies that have informed current NICE guidelines for fosfomycin use in UTI. This table contains a brief summary of four studies from Europe/North America that are referenced by current NICE guidelines regarding the use of oral fosfomycin for treatment of UTI, including date of study, cohort location, study design and cure data. (DOCX 88Â kb
MOESM2 of Disease progression despite protective HLA expression in an HIV-infected transmission pair
Additional file 2: Figure S2. Sites of HLA-associated footprints in the donor from an HIV transmission pair at 8Â months post-diagnosis aligned to B and CRF01_AE clade consensus sequence. Epitopes restricted by the favourable alleles expressed by the donor, A*3201, B*1302 and B*1401, are shown
Additional file 1: of The MONARCH intervention to enhance the quality of antenatal and postnatal primary health services in rural South Africa: protocol for a stepped-wedge cluster-randomised controlled trial
MONARCH SWT protocol. Text S1: South African National Department of Health standard of care: PMTCT guidelines and basic antenatal care. Table S1. Minimum detectable differences in percentage points by outcome. (DOCX 25 kb
Additional file 2: of The MONARCH intervention to enhance the quality of antenatal and postnatal primary health services in rural South Africa: protocol for a stepped-wedge cluster-randomised controlled trial
MONARCH SWT protocol. Description of data: SPIRIT checklist. (DOCX 28 kb
'Hepitopes': A Database of HLA Class I Epitopes in Hepatitis B Virus
This is a spreadsheet containing the results of a systematic literature review to identify and curate all known and putative HLA Class I epitopes in hepatitis B virus (HBV). <div>
<p>We performed our literature review in January 2016, searching Medline and Embase via the OVID search interface made available by the University of Oxford. No date restrictions were
imposed; Medline was searched from 1946-2016 and Embase from 1974-2016. The relevant subject headings
for Epitopes, HLA Antigens, CD8 Antigens and Hepatitis B from the thesauri
(MESH and EMTREE) were exploded and searched. In addition the terms epitope*
(to pick up singular and plural) and Hepatitis B and HBV
were searched in the title and abstract fields. We also identified additional references by searching the
bibliographies of relevant articles. </p><p>As well as details of each citation, we recorded the HBV protein and sequence-numbered location of each epitope (based on a published reference strain; Liu WC, et al. Aligning to the sample-specific reference sequence
to optimize the accuracy of next-generation sequencing analysis for hepatitis B
virus. <i>Hepatol Int</i> 2016;10:147-157).</p>
<p>Each citation was reviewed by a primary reviewer and then again by a second expert to ensure the records are as accurate as possible. </p><p>Over time, we aim to update and refine the dataset such that it becomes a growing resource for virologists, immunologists and those in the field of vaccine design.</p><p>A live interactive version can be viewed at http://www.expmedndm.ox.ac.uk/hepitopes.</p><p>The visualisation code can be viewed at <a href="https://github.com/ox-it/hepitopes" rel="noreferrer" target="_blank">https://github.com/ox-it/hepitopes</a>. </p><p>As the database is updated and refined, we will submit updated versions to Figshare. In parallel, we have uploaded a static version to Oxford Research Archive (ORA) at the point of initial publication; DOI: 10.5287/bodleian:zr0VAr78q</p>
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