Nanoscale Arrangement of Proteins by Single-Molecule Cut-and-Paste

Protein-based nanostructures are key to the organization of life and it is their precise arrangement, which determines their specific functions. A single-molecule approach for the directed assembly of protein arrangements allows for a controlled composition of systems based on protein components. Applying antibodies and antigenic peptide tags we utilized the Single-Molecule Cut-and-Paste (SMC&P) technique for the handling of single proteins. Protein–DNA complexes could be arranged to complex patterns with the functionality of the protein part remaining unimpaired

Additional file 2: of The dose distribution in dominant intraprostatic tumour lesions defined by multiparametric MRI and PSMA PET/CT correlates with the outcome in patients treated with primary radiation therapy for prostate cancer

Table S2. Spearman’s rho test. Correlation between the three dose parameters in the respective three volumes was analyzed. A weaker correlation between the Dmin values compared to the Dmean and Dmax values, respectively, was observed. Spearman’s rho values are listed. The respective p values were all < 0.001. (PDF 135 kb

Selective Photooxidation Reactions using Water-Soluble Anthraquinone Photocatalysts

The aerobic organocatalytic oxidation of alcohols was achieved by using water-soluble sodium anthraquinone sulfonate. Under visible-light activation, this catalyst mediated the aerobic oxidation of alcohols to aldehydes and ketones. The photo-oxyfunctionalization of alkanes was also possible under these conditions.BT/Biocatalysi

Additional file 3: of Focal dose escalation for prostate cancer using 68Ga-HBED-CC PSMA PET/CT and MRI: a planning study based on histology reference

A. Additional information on TCP calculation / B. Additional information on NTCP calculation. (PDF 278 kb

Additional file 1: of Focal dose escalation for prostate cancer using 68Ga-HBED-CC PSMA PET/CT and MRI: a planning study based on histology reference

Table S1. Patient characteristics. (PDF 106 kb