43 research outputs found

    Diraya.media—learning media literacy with and from media activists

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    Taking stock of media activist initiatives in the Southwest Asia and North Africa (SWANA) region, this article discusses findings from case study research informing the media education platform “diraya.media.” Through participatory methodology, the case studies and the bilingual (Arabic/English) website aim to analyze and strengthen local media literacy pedagogies by learning with and from media activists in the region. This article reports on six case studies of SWANA-based media activist organizations and pedagogical material for the media literacy classroom. The goal is to reflect and discuss the methodological and theoretical ramifications of Diraya as a pedagogical space for reflection and knowledge exchange between media activists and other learners in the region and beyond. Drawing on the participating activists’ experiences, Diraya is embedded in the turn toward radical media education and civic media literacies, contributing to (1) de-Westernizing media literacy education, (2) creating more learning materials based on local activist knowledge as important resources to increase media literacy, and (3) enabling of long-term collaborations by archiving and making public experiences from SWANA-based media activists

    Greater Tuberosity Fractures after RTSA: A Matched Group Analysis

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    Periprosthetic fractures, such as acromial and spine fractures, are known complications following implantation of reverse shoulder arthroplasty (RTSA). The entity of greater tuberosity fractures (GTF) has rarely been studied in the literature. The purpose of this study was to analyze the outcome of postoperative greater tuberosity fractures after RTSA compared to a matched control group. The main findings of this study are that a GTF after RTSA is associated with worse clinical outcome scores (mean absolute CS 50 ± 19 (p = 0.032); SSV 63% ± 26 (p = 0.022); mean force 1 kg ± 2 kg (p = 0.044)) compared with the control group (mean absolute CS 62 ± 21; SSV 77% ± 29; mean force 2 kg ± 2 kg). In terms of postoperative range of motion, the fracture group was significantly worse in terms of external rotation (17° ± 19° vs. 30° ± 19° (p = 0.029)). Internal rotation, flexion, as well as abduction of the shoulder appear to be unaffected (internal rotation GTF 4 ± 2, control group 5 ± 3 (p = 0.138); flexion GTF 102° ± 28°, control group 114° ± 27° (p = 0.160); abduction GTF 109° ± 42°, control group 120° ± 39° (p = 0.317))

    Isogeometric dual mortar methods for computational contact mechanics

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    International audienceIn recent years, isogeometric analysis (IGA) has received great attention in many fields of computational mechanics research. Especially for computational contact mechanics, an exact and smooth surface representation is highly desirable. As a consequence, many well-known finite e lement m ethods a nd a lgorithms f or c ontact m echanics h ave b een t ransferred t o I GA. I n t he present contribution, the so-called dual mortar method is investigated for both contact mechanics and classical domain decomposition using NURBS basis functions. In contrast to standard mortar methods, the use of dual basis functions for the Lagrange multiplier based on the mathematical concept of biorthogonality enables an easy elimination of the additional Lagrange multiplier degrees of freedom from the global system. This condensed system is smaller in size, and no longer of saddle point type but positive definite. A very simple and commonly used element-wise construction of the dual basis functions is directly transferred to the IGA case. The resulting Lagrange multiplier interpolation satisfies discrete inf–sup stability and biorthogonality, however, the reproduction order is limited to one. In the domain decomposition case, this results in a limitation of the spatial convergence order to O(h 3 /2) in the energy norm, whereas for unilateral contact, due to the lower regularity of the solution, optimal convergence rates are still met. Numerical examples are presented that illustrate these theoretical considerations on convergence rates and compare the newly developed isogeometric dual mortar contact formulation with its standard mortar counterpart as well as classical finite elements based on first and second order Lagrange polynomials

    Vestigial auriculomotor activity indicates the direction of auditory attention in humans

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    Unlike dogs and cats, people do not point their ears as they focus attention on novel, salient, or task-relevant stimuli. Our species may nevertheless have retained a vestigial pinna-orienting system that has persisted as a 'neural fossil’ within in the brain for about 25 million years. Consistent with this hypothesis, we demonstrate that the direction of auditory attention is reflected in sustained electrical activity of muscles within the vestigial auriculomotor system. Surface electromyograms (EMGs) were taken from muscles that either move the pinna or alter its shape. To assess reflexive, stimulus-driven attention we presented novel sounds from speakers at four different lateral locations while the participants silently read a boring text in front of them. To test voluntary, goal-directed attention we instructed participants to listen to a short story coming from one of these speakers, while ignoring a competing story from the corresponding speaker on the opposite side. In both experiments, EMG recordings showed larger activity at the ear on the side of the attended stimulus, but with slightly different patterns. Upward movement (perking) differed according to the lateral focus of attention only during voluntary orienting; rearward folding of the pinna’s upper-lateral edge exhibited such differences only during reflexive orienting. The existence of a pinna-orienting system in humans, one that is experimentally accessible, offers opportunities for basic as well as applied science

    Why is female gender associated with poorer clinical outcome after reverse total shoulder arthroplasty?

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    INTRODUCTION: There is a lack of gender-specific research after reverse total shoulder arthroplasty (RTSA). While previous studies have documented worse outcome in women - a more thorough understanding of why outcome may differ is needed. We therefore asked: (1) Are there gender-specific differences in pre- and postoperative clinical scores, complications, surgery-related parameters and demographics? (2) Is female gender an independent risk factor for poorer clinical outcome after RTSA? (3) If so, why is female gender associated with poorer outcome after RTSA? MATERIALS AND METHODS: Between 2005 and 2019, 987 primary RTSAs were performed in our institution. After exclusion criteria were applied, data of 422 female and 271 male patients were analyzed. Clinical outcome (absolute/relative Constant Score (a/rCS) and Subjective Shoulder Value (SSV)), complications (intra- and/or postoperative fracture, loosening), surgery-related parameters (indication, implant related characteristics) and demographics (age, gender, body mass index (BMI) and number of previous surgeries) were evaluated. Pre- and postoperative radiographs were analyzed (Critical Shoulder Angle (CSA), Deltoid-Tuberosity Index (DTI), Reverse Shoulder Angle (RSA), Lateralization (LSA) and Distalization Shoulder Angle (DSA)). RESULTS: Preoperative clinical scores (aCS, rCS, SSV and pain level) as well as postoperative clinical outcome (aCS, rCS) were significantly worse in women. However, the improvement between pre- and postoperative outcome was significantly higher in female patients for rCS (p=0.037), internal rotation (p<0.001) and regarding pain (p<0.001). Female patients had a significantly higher number of intraoperative as well as postoperative fractures (24.9% vs. 11.4%, p<0.001). The proportion of female patients with a DTI<1.4 was significantly higher than in males (p=0.01). Female gender was an independent negative predictor for postoperative rCS (p=0.047, Coefficient -0.084) and pain (p=0.017, Coefficient -0.574). In addition to female sex per se being a predictive factor of worse outcome, females were significantly more likely to meet two of the three most significant predictive factors: (1) significantly worse preoperative clinical scores and (2) higher rate of intra- and/or postoperative fractures. CONCLUSIONS: Female sex is a very weak, but isolated, negative predictive factor that negatively affects objective clinical outcome (rCS) after RTSA. However, differences did not reach the minimal clinically important difference (MCID) and it is not a predictor for subjective outcome (SSV). The main reason for worse outcome in female patients seems to be a combination of higher preoperative disability and higher incidence of fractures. To improve the outcome of women, all measures that contribute to the reduction of perioperative fracture risk should be utilized

    Human brain anatomy reflects separable genetic and environmental components of socioeconomic status

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    Socioeconomic status (SES) correlates with brain structure, a relation of interest given the long-observed relations of SES to cognitive abilities and health. Yet, major questions remain open, in particular, the pattern of causality that underlies this relation. In an unprecedently large study, here, we assess genetic and environmental contributions to SES differences in neuroanatomy. We first establish robust SES–gray matter relations across a number of brain regions, cortical and subcortical. These regional correlates are parsed into predominantly genetic factors and those potentially due to the environment. We show that genetic effects are stronger in some areas (prefrontal cortex, insula) than others. In areas showing less genetic effect (cerebellum, lateral temporal), environmental factors are likely to be influential. Our results imply a complex interplay of genetic and environmental factors that influence the SES-brain relation and may eventually provide insights relevant to policy

    Simple Questionnaires to Improve Pooling Strategies for SARS-CoV-2 Laboratory Testing

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    Background: Liberal PCR testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is key to contain the coronavirus disease 2019 (COVID-19) pandemic. Combined multi-sample testing in pools instead of single tests might enhance laboratory capacity and reduce costs, especially in low- and middle-income countries. Objective: The purpose of our study was to assess the value of a simple questionnaire to guide and further improve pooling strategies for SARS-CoV-2 laboratory testing. Methods: Pharyngeal swabs for SARS-CoV-2 testing were obtained from healthcare and police staff, hospital inpatients, and nursing home residents in the southwestern part of Germany. We designed a simple questionnaire, which included questions pertaining to a suggestive clinical symptomatology, recent travel history, and contact with confirmed cases to stratify an individual’s pre-test probability of having contracted COVID-19. The questionnaire was adapted repeatedly in face of the unfolding pandemic in response to the evolving epidemiology and observed clinical symptomatology. Based on the response patterns, samples were either tested individually or in multi-sample pools. We compared the pool positivity rate and the number of total PCR tests required to obtain individual results between this questionnaire-based pooling strategy and randomly assembled pools. Findings: Between March 11 and July 5, 2020, we processed 25,978 samples using random pooling (n = 6,012; 23.1%) or questionnaire-based pooling (n = 19,966; 76.9%). The overall prevalence of SARS-CoV-2 was 0.9% (n = 238). Pool positivity (14.6% vs. 1.2%) and individual SARS-CoV-2 prevalence (3.4% vs. 0.1%) were higher in the random pooling group than in the questionnaire group. The average number of PCR tests needed to obtain the individual result for one participant was 0.27 tests in the random pooling group, as compared to 0.09 in the questionnaire-based pooling group, leading to a laboratory capacity increase of 73% and 91%, respectively, as compared to single PCR testing. Conclusions: Strategies that combine pool testing with a questionnaire-based risk stratification can increase laboratory testing capacities for COVID-19 and might be important tools, particularly in resource-constrained settings

    Introduction. Vivir bien / Buen vivir and post-neoliberal development paths in Latin America : scope, strategies and the realities of implementation

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    Neoliberalism has economic, political, sociocultural, and environmental consequences that are known to cause imbalances across the globe (Navarro, 2020). The financial crisis that began in 2008 in the economic centers of the Global North has been steadily spreading to low- and middle-income countries, including much of Latin America. Political leaders around the world are unable to confront the contradictions of market-led forms of development that deepen socioeconomic inequalities while unsustainably extracting the natural resources required to maintain consumption-driven forms of economic growth. At the same time, economic growth appears to be the prerequisite for responding to immediate local needs and bringing social groups and entire countries out of poverty. Awareness of and resistance to the structural inconsistencies of the neoliberal globalization project at the margins, led by people from countries at the so-called periphery of the world system, had already emerged in the crisis of the 1980s (Wallerstein, 1984). This was a resistance that sometimes emerged from civil society rather than being led by traditional political and economic elites (Petras, 2011). Having survived the lost decade of the 1980s and beyond, Latin America perfectly illustrates the crisis of legitimacy of the neoliberal revolution and the sociopolitical counterrevolution of civil-society-led alternatives. It is in this context that we are witnessing innovative ideas emerge from communities and subjects that have historically been economically, politically, and culturally marginalized. Latin America’s upheaval and contestation have their roots in indigenous epistemologies—epistemologies of the South (Santos, 2015)—and practices. Where indigenous groups have become a newly empowered political subject (Postero, 2006), as in Bolivia, the repercussions of these political transitions include the incorporation of indigenous knowledge and practices into the roadmap for alternative, “refounded” (Artaraz, 2012) versions of these societies. As a result, both Bolivia and Ecuador have seen the introduction of indigenous concepts of vivir bien (living well) or buen vivir (good living) into their constitutions, national development plans, and public policies. When the concept of vivir bien was added to these constitutions, possibilities were opened for countries around the region to experiment with the meaning of sumak kawsay/buen vivir and suma qamaña/vivir bien and the ways in which a range of understandings of these terms could be translated into policy (Asamblea Constituyente, 2008). Versions of the concept have also gained salience in other Latin American countries, from Venezuela to Nicaragua

    Group B streptococcus infection during pregnancy and infancy: estimates of regional and global burden.

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    BACKGROUND: Group B streptococcus (GBS) colonisation during pregnancy can lead to invasive GBS disease (iGBS) in infants, including meningitis or sepsis, with a high mortality risk. Other outcomes include stillbirths, maternal infections, and prematurity. There are data gaps, notably regarding neurodevelopmental impairment (NDI), especially after iGBS sepsis, which have limited previous global estimates. In this study, we aimed to address this gap using newly available multicountry datasets. METHODS: We collated and meta-analysed summary data, primarily identified in a series of systematic reviews published in 2017 but also from recent studies on NDI and stillbirths, using Bayesian hierarchical models, and estimated the burden for 183 countries in 2020 regarding: maternal GBS colonisation, iGBS cases and deaths in infants younger than 3 months, children surviving iGBS affected by NDI, and maternal iGBS cases. We analysed the proportion of stillbirths with GBS and applied this to the UN-estimated stillbirth risk per country. Excess preterm births associated with maternal GBS colonisation were calculated using meta-analysis and national preterm birth rates. FINDINGS: Data from the seven systematic reviews, published in 2017, that informed the previous burden estimation (a total of 515 data points) were combined with new data (17 data points) from large multicountry studies on neurodevelopmental impairment (two studies) and stillbirths (one study). A posterior median of 19·7 million (95% posterior interval 17·9-21·9) pregnant women were estimated to have rectovaginal colonisation with GBS in 2020. 231 800 (114 100-455 000) early-onset and 162 200 (70 200-394 400) late-onset infant iGBS cases were estimated to have occurred. In an analysis assuming a higher case fatality rate in the absence of a skilled birth attendant, 91 900 (44 800-187 800) iGBS infant deaths were estimated; in an analysis without this assumption, 58 300 (26 500-125 800) infant deaths from iGBS were estimated. 37 100 children who recovered from iGBS (14 600-96 200) were predicted to develop moderate or severe NDI. 40 500 (21 500-66 200) maternal iGBS cases and 46 200 (20 300-111 300) GBS stillbirths were predicted in 2020. GBS colonisation was also estimated to be potentially associated with considerable numbers of preterm births. INTERPRETATION: Our analysis provides a comprehensive assessment of the pregnancy-related GBS burden. The Bayesian approach enabled coherent propagation of uncertainty, which is considerable, notably regarding GBS-associated preterm births. Our findings on both the acute and long-term consequences of iGBS have public health implications for understanding the value of investment in maternal GBS immunisation and other preventive strategies. FUNDING: Bill & Melinda Gates Foundation
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