How do high performance work systems influence organizational innovation in professional service firms?

Purpose - The aim of this paper is examine how a system of human resource management (HRM) practices, labelled high performance work systems (HPWS), influences organizational innovation in professional service firms (PSFs). In this study, innovation in PSFs is seen as an indicator of firm performance and is calculated as the revenue per person generated from new clients and new services respectively. Design/methodology/approach– Quantitative data was collected from 195 Managing Partners, HR Managers or experienced Partners in 120 Irish accounting firms. Hierarchical regression analysis was used to test the hypotheses. Findings - The analysis results indicate strong support for the mediating role of employees’ innovative work behaviours in the relationship between HPWS and two types of PSFs’ innovation performance. Practical implications - Managers need to effectively adopt and implement innovation-based HRM practices to encourage and support employees’ creative thinking and innovation. Through the adoption and utilization of these practices managers can enhance the firm’s innovation and its performance. Originality/value - This study contributes to our understanding of the link between HRM and firm innovation by explicating a pathway between these variables. This study also generalizes consistent findings on the HRM-firm innovation relationship to a different context, i.e. professional service firms

Convolutional Pitch Target Approximation Model for Speech Synthesis

In this paper, we investigate pitch contour modelling in speech synthesis based on segmental units. A convolutional pitch target approximation model is proposed. This model allows jointly stochastic modelling of framewise pitch and pitch contour of longer units, of which the intuitive relations are revealed by a convolutional target approximation filter. The pitch contour is stylized by a linear representation called pitch target. In synthesis stage, the likelihood of the framewise model and the pitch target model are jointly maximized using a Toeplitz matrix representing the discrete convolutional filter

Shear behavior of a shear thickening fluid-impregnated aramid fabrics at high shear rate

Shear-thickening fluid-impregnated aramid (STF-im-AR) fabrics have been manufactured for advanced soft body armor applications for which they provide improved ballistic and stab resistances. It is not yet clear whether or not such improvements can be attributed solely to the STF. In this study, the rate-dependent behavior of an STF-im-AR fabric was investigated at the fabric level, using uniaxial tensile, bias-extension, and picture-frame tests. Rate-dependent behavior of the STF-im-AR fabric was observed during uniaxial tensile testing; however, the effect of the STF treatment was slight and consistent with only the inherent effect of the polymeric nature of its constituent fibers. The shear rigidity of the STF-im-AR fabric increased, due to the presence of the STF and the sensitivity of the fabric's shear stiffness to changes in the shear strain rate also increased slightly. This rate-sensitive shear stiffness of STF-im-AR fabrics may contribute to improved ballistic and stab resistances

Syllable-based Pitch Encoding for Low Bit Rate Speech Coding with Recognition/Synthesis Architecture

Current HMM-based low bit rate speech coding systems work with phonetic vocoders. Pitch contour coding (on frame or phoneme level) is usually fairly orthogonal to other speech coding parameters. We make an assumption in our work that the speech signal contains supra-segmental cues. Hence, we present encoding of the pitch on the syllable level, used in the framework of a recognition/synthesis speech coder with phonetic vocoder. The results imply that high accuracy pitch contour reconstruction with negligible speech quality degradation is possible. The proposed pitch encoding technique operates on 30 - 35 bits per second

Construction and evaluation of multisite recombinatorial (Gateway) cloning vectors for Gram-positive bacteria

<p>Abstract</p> <p>Background</p> <p>The Gateway recombinatorial cloning system allows easy and rapid joining of DNA fragments. Here we report the construction and evaluation of three different Gram-positive vectors that can be used with the Multisite Gateway cloning system to rapidly produce new gene arrangements in plasmid constructs for use in a variety of Gram-positive bacteria.</p> <p>Results</p> <p>Comparison of patterns of reporter gene expression with conventionally constructed clones show that the presence of residual recombination (att) sites does not have an effect on patterns of gene expression, although overall levels of gene expression may vary. Rapid construction of these new vectors allowed vector/gene combinations to be optimized following evaluation of plasmid constructs in different bacterial cells and demonstrates the benefits of plasmid construction using Gateway cloning.</p> <p>Conclusion</p> <p>The residual <it>att </it>sites present after Gateway cloning did not affect patterns of promoter induction in Gram-positive bacteria and there was no evidence of differences in mRNA stability of transcripts. However overall levels of gene expression may be reduced, possibly due to some post-transcriptional event. The new vectors described here allow faster, more efficient cloning in range of Gram-positive bacteria.</p

Perceived Sufficiency of Full-Field Digital Mammograms With and Without Irreversible Image Data Compression for Comparison with Next-Year Mammograms

Problems associated with the large file sizes of digital mammograms have impeded the integration of digital mammography with picture archiving and communications systems. Digital mammograms irreversibly compressed by the novel wavelet Access Over Network (AON) compression algorithm were compared with lossless-compressed digital mammograms in a blinded reader study to evaluate the perceived sufficiency of irreversibly compressed images for comparison with next-year mammograms. Fifteen radiologists compared the same 100 digital mammograms in three different comparison modes: lossless-compressed vs 20:1 irreversibly compressed images (mode 1), lossless-compressed vs 40:1 irreversibly compressed images (mode 2), and 20:1 irreversibly compressed images vs 40:1 irreversibly compressed images (mode 3). Compression levels were randomly assigned between monitors. For each mode, the less compressed of the two images was correctly identified no more frequently than would occur by chance if all images were identical in compression. Perceived sufficiency for comparison with next-year mammograms was achieved by 97.37% of the lossless-compressed images and 97.37% of the 20:1 irreversibly compressed images in mode 1, 97.67% of the lossless-compressed images and 97.67% of the 40:1 irreversibly compressed images in mode 2, and 99.33% of the 20:1 irreversibly compressed images and 99.19% of the 40:1 irreversibly compressed images in mode 3. In a random-effect analysis, the irreversibly compressed images were found to be noninferior to the lossless-compressed images. Digital mammograms irreversibly compressed by the wavelet AON compression algorithm were as frequently judged sufficient for comparison with next-year mammograms as lossless-compressed digital mammograms

Cyclin Y inhibits plasticity-induced AMPA receptor exocytosis and LTP

Cyclin Y (CCNY) is a member of the cyclin protein family, known to regulate cell division in proliferating cells. Interestingly, CCNY is expressed in neurons that do not undergo cell division. Here, we report that CCNY negatively regulates long-term potentiation (LTP) of synaptic strength through inhibition of AMPA receptor trafficking. CCNY is enriched in postsynaptic fractions from rat forebrain and is localized adjacent to postsynaptic sites in dendritic spines in rat hippocampal neurons. Using live-cell imaging of a pH-sensitive AMPA receptor, we found that during LTP-inducing stimulation, CCNY inhibits AMPA receptor exocytosis in dendritic spines. Furthermore, CCNY abolishes LTP in hippocampal slices. Taken together, our findings demonstrate that CCNY inhibits plasticity-induced AMPA receptor delivery to synapses and thereby blocks LTP, identifying a novel function for CCNY in post-mitotic cells

Incremental Syllable-Context Phonetic Vocoding

Current very low bit rate speech coders are, due to complexity limitations, designed to work off-line. This paper investigates incremental speech coding that operates real-time and incrementally (i.e., encoded speech depends only on already-uttered speech without the need of future speech information). Since human speech communication is asynchronous (i.e., different information flows being simultaneously processed), we hypothesised that such an incremental speech coder should also operate asynchronously. To accomplish this task, we describe speech coding that reflects the human cortical temporal sampling that packages information into units of different temporal granularity, such as phonemes and syllables, in parallel. More specifically, a phonetic vocoder — cascaded speech recognition and synthesis systems — extended with syllable-based information transmission mechanisms is investigated. There are two main aspects evaluated in this work, the synchronous and asynchronous coding. Synchronous coding refers to the case when the phonetic vocoder and speech generation process depend on the syllable boundaries during encoding and decoding respectively. On the other hand, asynchronous coding refers to the case when the phonetic encoding and speech generation processes are done independently of the syllable boundaries. Our experiments confirmed that the asynchronous incremental speech coding performs better, in terms of intelligibility and overall speech quality, mainly due to better alignment of the segmental and prosodic information. The proposed vocoding operates at an uncompressed bit rate of 213 bits/sec and achieves an average communication delay of 243 ms