Parameterization of NMR relaxation curves in terms of logarithmic moments of the relaxation time distribution

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 668119 (project “IDentiFY”). We thank Dr. Reiner Zorn for helpful comments on his article [7]; Dr. Oliver Neudert and Dr. Carlos Mattea for introduction to the field-cycling relaxometry and their suggestions about a test sample; and Prof. Dr. Michael Vogel for permission to use the 7Li stimulated-echo data.Peer reviewedPublisher PD

Geopetrological model of formation diamond-bearing fluid-explosive breccia structures (urals type)

Geopetrological model of diamond-bearing fluid-explosive breccia formations is a well-structured system of the features that are typical of several similar formations in the Cis-Ural and West Ural areas of the Perm Krai. The model reflects a number of basic common factors in these structures’ morphology, their rock composition and the conditions for their formation. Regional and local geological positions featuring diamond-bearing formations as well as the parameters common for their widespread formation areas are characterized. The necessity of mineralogical and geochemical studies of black sand, while prospecting for diamond-bearing targets is highlighted. This will help identify specific mineral associations and geochemical anomalies typical of these widespread formation areas. The description of the geological structure, which the best-studied Efimov deposit, is given in detail. The description of this deposit is used as an example of illustrating the shape of breccia bodies and their polyphase structure, as well as describing their texture and rock structure specifics. Particular attention is paid to the petrographic characteristics of all kinds of fluid-explosive breccias, which to a different extent contain clastic, protomagmatic and newly formed fluidogenic material. The paper gives the characteristics and specifics of mineral grains of various origin, many of which are abundant in gas-liquid inclusions, characterized by block extinction, while quartz possess planar elements. Brought into focus are the differences in the diamond bearing capacity of rocks belonging to different successive evolution phases of fluid breccia formations. The model considered in the paper will make it possible in the course of studies of newly discovered breccia structures with a limited number of parameters to predict their missing features and assessment criteria with respect to possible beneficial mineralization

Filamentation of collimated Ti:sapphire-laser pulses in water

The results of experimental studies of the spatial characteristics of multiple filamentation terawatt femtosecond Ti:Salaser in water are presented. With an increase in initial power laser pulses increases the number of filaments, the length of the field is increased filamentation and reducing the length of the filaments have been shown. The distribution of the filaments in the longitudinal direction of the field of multiple filamentation has a maximum cross-sectional filament is shifted from the center to the periphery of the beam at the end region of filamentation. The minimum diameter of the beam on the track corresponds to the position of the maximum number of filaments. After the point of maximum impulse essentially loses energy in the initial direction of propagation. Upon reaching the pulse power 2 104 Pcr of multiple filamentation area is formed of a hollow cone, the apex directed to the radiation source

Multiple filamentation Ti:Sapphire-laser pulses in water

The results of experimental studies of the spatial characteristics of multiple filamentation terawatt femtosecond Ti:Salaser in water are presented. With an increase in initial power laser pulses increases the number of filaments, the length of the field is increased filamentation and reducing the length of the filaments have been shown. The distribution of the filaments in the longitudinal direction of the field of multiple filamentation has a maximum cross-sectional filament is shifted from the center to the periphery of the beam at the end region of filamentation. The minimum diameter of the beam on the track corresponds to the position of the maximum number of filaments. After the point of maximum impulse essentially loses energy in the initial direction of propagation. Upon reaching the pulse power 2 104 Pcr of multiple filamentation area is formed of a hollow cone, the apex directed to the radiation source

Filamentation of focused and collimated laser beams in liquids

Experimental results of investigations into the transformation of the spectral and spatial characteristics of femtosecond collimated and focused Ti:Sapphire-laser beams with wavelengths of 800 and 400 nm upon filamentation in continuous liquid media are presented. It is shown that broadening of the laser pulse spectrum due to phase self-modulation in the medium with a cubic nonlinearity depends on the pulse power and beam diameter. Dependences of the number of filaments, width of laser radiation spectrum, nonlinear focusing distance, and diameter of the filamentation region on the laser pulse power are measured. The existence of a relative power interval in which the explosive growth of the number of filaments occurs, is established. © (2015) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only

Multiple filamentation of laser pulses in the glass

Results are presented of experiments on investigation of the spatial characteristics of multi-filamentation region of giga- and terawatt pulses of a Ti:sapphire laser in a glass. Dependences are obtained of the coordinate of the beginning of filamentation region, number of filaments, their distribution along the laser beam axis, and length of filaments on the pulse power. It is shown that with increasing radiation power, the number of filaments in the multi-filamentation region decreases, whereas the filament diameter has a quasiconstant value for all powers realized in the experiments. It is shown that as a certain power of the laser pulse with Gauss energy density distribution is reached, the filamentation region acquires the shape of a hollow cone with apex directed toward the radiation source

Filamentation of collimated Ti:sapphire-laser pulses in the glass

The results of experiments to study the spatial characteristics of multiple filamentation gigawatt laser pulses in the glass are presented. It is shown that with increasing pulse power multiple filamentation region increases in length and diameter, the distribution of filaments within the region has a maximum value when the power > 105 Pcr area filamentation takes the form of a hollow cone, the apex directed to the source of the laser radiation

Development, production and characterization of SARS-CoV-2 virus-like particles (Coronaviridae: <i>Orthocoronavirinae: Betacoronavirus: Sarbecovirus</i>)

Introduction. The COVID-19 pandemic caused by SARS-CoV-2 has created serious health problems worldwide. The most effective way to prevent the occurrence of new epidemic outbreaks is vaccination. One of the modern and effective approaches to vaccine development is the use of virus-like particles (VLPs). The aim of the study is to develop a technology for production of VLP based on recombinant SARS-CoV-2 proteins (E, M, N and S) in insect cells. Materials and methods. Synthetic genes encoding coronavirus proteins E, M, N and S were used. VLP with various surface proteins of strains similar to the Wuhan virus, Delta, Alpha and Omicron were developed and cloned into the pFastBac plasmid. The proteins were synthesized in the baculovirus expression system and assembled into VLP in the portable Trichoplusia ni cell. The presence of insertion in the baculovirus genome was determined by PCR. ELISA and immunoblotting were used to study the antigenic activity of VLP. VLP purification was performed by ultracentrifugation using 20% sucrose. Morphology was assessed using electron microscopy and dynamic light scattering. Results. VLPs consisting of recombinant SARS-CoV-2 proteins (S, M, E and N) were obtained and characterized. The specific binding of antigenic determinants in synthesized VLPs with antibodies to SARS-CoV-2 proteins has been demonstrated. The immunogenic properties of VLPs have been studied. Conclusion. The production and purification of recombinant VLPs consisting of full-length SARS-CoV-2 proteins with a universal set of surface antigens have been developed and optimized. Self-assembling particles that mimic the coronavirus virion induce a specific immune response against SARS-CoV-2