Vaikų steroidams jautraus nefrozinio sindromo gydymo prednizolonu ir prednizolonu kartu su fusido rūgštimi lyginamasis tyrimas

Background. There are several reports in the literature indicating that fusidic acid owns functions similar to those of cyclosporin. As cyclosporin has effectively been used in frequently relpsing steroid-responsive nephrotic syndrome we carried out this study to determine whether fusidic acid used along with prednisolone diminishes rate of steroid-responsive nephrotic syndrome relapses in children. Patients and methods. The patients were randomly allocated to receive either prednisolone alone or prednisolone plus fusidic acid for two months in standard doses..

Nephrogenic diabetes insipidus in a large family

Hereditary nephrogenic diabetes insipidus is a rare disease. We describe here three brothers with this disease from a big family consisting of 10 siblings. The case is undoubtedly X-linked because the sufferers are only boys, one of them with a different father. The illness was noticed rather late, namely, at the ages of approximately 7, 6 and 5 years. Possibly, this is a particular characteristic of this family, because the disease is usually diagnosed before the age of two years. In the oldest brother (at present 15 years old) epicystotomy was performed at the time of diagnosis because of polyuria, hydroureteronephrosis and bladder hypotonia; the intervention caused a urinary tract infection leading to chronic pyelonephritis and renal scarring. No urologic intervention was necessary in the younger brothers, because their illness was noticed and treatment started somewhat earlier. This case shows that polydipsia and polyuria should always be assessed properly to disclose their causes

Hemolytic-uremic syndrome in Lithuania over the period 1990-2004

More than 80 cases of the hemolytic-uremic syndrome were registered in Lithuania over the period 1990–2004. The incidence of this syndrome fluctuated annually; higher incidence rates were observed in 1990–1993, 1998–1999 and 2003–2004, however, there was no overall increase in morbidity over the 15-year period. Most cases occurred in the first two years of life; besides, girls suffered slightly more often than boys. At least in 80% of cases the illness was typical, i. e. was associated with diarrhea. In general, the data correspond to the findings of other scientists

Ūminis glomerulonefritas, susijęs su mikoplazmine pneumonija

Straipsnyje aprašomas gana retas atvejis – ūminis glomerulonefritas, susijęs su mikoplazmine pneumonija. Literatūros duomenimis, mikoplazminė infekcija gali būti susijusi su įvairaus pobūdžio inkstų pažeidimu, tačiau mūsų stebėtu atveju inkstų liga nedaug skyrėsi nuo klasikinio ūminio poinfekcinio glomerulonefrito. Ryškiausias skirtumas – tai, kad inkstų ligos požymių atsirado beveik vienu metu su kvėpavimo takų ligos simptomais, o ne praėjus bent vienai savaitei. Ligos eiga ir baigtis buvo gera

Resistance in respiratory tract pathogens and antimicrobial use in Icelandic and Lithuanian children

To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldTo assess resistance rates among respiratory tract pathogens and antimicrobial usage of children in Iceland and Lithuania, and to correlate usage patterns with resistance rates, nasopharyngeal swabs were taken from healthy children attending day-care centres in Reykjavik (n = 6) and Vilnius (n = 13), and cultured for pneumococci, Haemophilus influenzae and Moraxella catarrhalis. Information about recent antimicrobial use was obtained by a questionnaire. 50% and 51% carried pneumococci, 59% and 67% carried H. influenzae and 60% and 46% carried M. catarrhalis, in Reykjavik (n = 297) and Vilnius (n = 508), respectively. The prevalence of penicillin non-susceptible pneumococci was 11% in Reykjavik (mainly serotype 6B) and 5% in Vilnius (mainly 23F). At the time of sampling 3% of the children in Reykjavik and 8% in Vilnius were receiving antimicrobials. Children carrying penicillin non-susceptible pneumococci had used antimicrobials more frequently in the preceding month and this was significant for the Icelandic children (p < 0.0002). Antimicrobial use was more common in Vilnius than in Reykjavik, yet antimicrobial resistance was more common in Reykjavik. Resistance rates cannot be predicted only on the basis of recent antimicrobial use