4,031 research outputs found
Nanolithography with metastable helium atoms in a high-power standing-wave light field
We have created periodic nanoscale structures in a gold substrate with a
lithography process using metastable triplet helium atoms that damage a
hydrofobic resist layer on top of the substrate. A beam of metastable helium
atoms is transversely cooled and guided through an intense standing-wave light
field. Compared to commonly used low-power optical masks, a high-power light
field (saturation parameter of 10E7) increases the confinement of the atoms in
the standing-wave considerably, and makes the alignment of the experimental
setup less critical. Due to the high internal energy of the metastable helium
atoms (20 eV), a dose of only one atom per resist molecule is required. With an
exposure time of only eight minutes, parallel lines with a separation of 542 nm
and a width of 100 nm (1/11th of the wavelength used for the optical mask) are
created.Comment: 5 pages, 5 figure
Influence of the lattice topography on a three-dimensional, controllable Brownian motor
We study the influence of the lattice topography and the coupling between
motion in different directions, for a three-dimensional Brownian motor based on
cold atoms in a double optical lattice. Due to controllable relative spatial
phases between the lattices, our Brownian motor can induce drifts in arbitrary
directions. Since the lattices couple the different directions, the relation
between the phase shifts and the directionality of the induced drift is non
trivial. Here is therefore this relation investigated experimentally by
systematically varying the relative spatial phase in two dimensions, while
monitoring the vertically induced drift and the temperature. A relative spatial
phase range of 2pi x 2pi is covered. We show that a drift, controllable both in
speed and direction, can be achieved, by varying the phase both parallel and
perpendicular to the direction of the measured induced drift. The experimental
results are qualitatively reproduced by numerical simulations of a simplified,
classical model of the system
Numerical simulations on the motion of atoms travelling through a standing-wave light field
The motion of metastable helium atoms travelling through a standing light
wave is investigated with a semi-classical numerical model. The results of a
calculation including the velocity dependence of the dipole force are compared
with those of the commonly used approach, which assumes a conservative dipole
force. The comparison is made for two atom guiding regimes that can be used for
the production of nanostructure arrays; a low power regime, where the atoms are
focused in a standing wave by the dipole force, and a higher power regime, in
which the atoms channel along the potential minima of the light field. In the
low power regime the differences between the two models are negligible and both
models show that, for lithography purposes, pattern widths of 150 nm can be
achieved. In the high power channelling regime the conservative force model,
predicting 100 nm features, is shown to break down. The model that incorporates
velocity dependence, resulting in a structure size of 40 nm, remains valid, as
demonstrated by a comparison with quantum Monte-Carlo wavefunction
calculations.Comment: 9 pages, 4 figure
A nonadiabatic semi-classical method for dynamics of atoms in optical lattices
We develop a semi-classical method to simulate the motion of atoms in a
dissipative optical lattice. Our method treats the internal states of the atom
quantum mechanically, including all nonadiabatic couplings, while position and
momentum are treated as classical variables. We test our method in the
one-dimensional case. Excellent agreement with fully quantum mechanical
simulations is found. Our results are much more accurate than those of earlier
semi-classical methods based on the adiabatic approximation.Comment: 7 pages, 5 figures, submitted to European Physical Journal
Demonstration of a controllable three-dimensional Brownian motor in symmetric potentials
We demonstrate a Brownian motor, based on cold atoms in optical lattices,
where isotropic random fluctuations are rectified in order to induce controlled
atomic motion in arbitrary directions. In contrast to earlier demonstrations of
ratchet effects, our Brownian motor operates in potentials that are spatially
and temporally symmetric, but where spatiotemporal symmetry is broken by a
phase shift between the potentials and asymmetric transfer rates between them.
The Brownian motor is demonstrated in three dimensions and the noise-induced
drift is controllable in our system.Comment: 5 pages, 4 figure
Influence of hand position on the near-effect in 3D attention
Voluntary reorienting of attention in real depth situations is characterized by an attentional bias to locations near the viewer once attention is deployed to a spatially cued object in depth. Previously this effect (initially referred to as the ‘near-effect’) was attributed to access of a 3D viewer-centred spatial representation for guiding attention in 3D space. The aim of this study was to investigate whether the near-bias could have been associated with the position of the response-hand, always near the viewer in previous studies investigating endogenous attentional shifts in real depth. In Experiment 1, the response-hand was placed at either the near or far target depth in a depth cueing task. Placing the response-hand at the far target depth abolished the near-effect, but failed to bias spatial attention to the far location. Experiment 2 showed that the response-hand effect was not modulated by the presence of an additional passive hand, whereas Experiment 3 confirmed that attentional prioritization of the passive hand was not masked by the influence of the responding hand on spatial attention in Experiment 2. The pattern of results is most consistent with the idea that response preparation can modulate spatial attention within a 3D viewer-centred spatial representation
Comparison of pap smear, visual inspection with acetic acid, human papillomavirus DNA-PCR testing and cervicography
Objective: To assess the test qualities of four screening methods to detect cervical intra-epithelial neoplasia in an urban African setting.
Method: Six hundred fiftythree women, attending a family planning clinic in Nairobi (Kenya), underwent four concurrent screening methods: pap smear, visual inspection with acetic acid (VIA), PCR for high risk human papillomavirus (HR HPV) and cervicography. The presence of cervical intra-epithelial neoplasia (CIN) was verified by colposcopy or biopsy.
Result: Sensitivity (for CIN2 or higher) and specificity (to exclude any CIN or cancer) were 83.3% (95% CI [73.6, 93.0]) and 94.6% (95% CI [92.6, 96.5]), respectively, for pap smear; 73.3% (95% CI [61.8, 84.9]) and 80.0% (95% CI [76.6, 83.4]) for VIA; 94.4% (95% CI [84.6, 98.8]) and 73.9% (95% CI [69.7, 78.2]) for HR HPV; and 72.3% (95% CI [59.1, 85.6]) and 93.2% (95% CI [90.8, 95.7]) for cervicography.
Conclusion: The pap smear had the highest specificity (94.6%) and HPV testing the highest sensitivity (94.4%). The visual methods, VIA and cervicography, were similar and showed an accuracy in between the former two tests
Preferences of Hungarian consumers for quality, access and price attributes of health care services — result of a discrete choice experiment
In 2010, a household survey was carried out in Hungary among 1037 respondents to study consumer preferences and willingness to pay for health care services. In this paper, we use the data from the discrete choice experiments included in the survey, to elicit the preferences of health care consumers about the choice of health care providers. Regression analysis is used to estimate the effect of the improvement of service attributes (quality, access, and price) on patients’ choice, as well as the differences among the socio-demographic groups. We also estimate the marginal willingness to pay for the improvement in attribute levels by calculating marginal rates of substitution. The results show that respondents from a village or the capital, with low education and bad health status are more driven by the changes in the price attribute when choosing between health care providers. Respondents value the good skills and reputation of the physician and the attitude of the personnel most, followed by modern equipment and maintenance of the office/hospital. Access attributes (travelling and waiting time) are less important. The method of discrete choice experiment is useful to reveal patients’ preferences, and might support the development of an evidence-based and sustainable health policy on patient payments
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