561 research outputs found

    Replicating and Extending Soroka, Fournier, and Nir:Negative News Increases Arousal and Negative Affect

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    The negativity bias hypothesis in political communication contends that people are more aroused by negative vs. positive news. Soroka et al. (2019) provide evidence for this negativity bias in a study in 17 countries across six continents. We find suggestive evidence for Soroka et al.’s (2019) central finding that negativity causes an increase in skin conductance levels in a conceptually close, well-powered, and preregistered replication. We extend Soroka et al. (2019) in three ways. First, we theorise, test, and confirm that negative (vs. positive) news causes an increase in activity of the corrugator major muscle above the eyebrow (using facial electromyography activity) and is associated with a negative affect. Second, we find people self-reporting negative news causes negative affect but that positive (instead of negative) news increases self-reported arousal. Third, we test Soroka et al.’s (2019) argument in another context, the Netherlands. Our article suggests that negative news is, especially, causing negative affect. Doing so, we contribute to the negativity bias argument in political communication research and, at the same time, show the importance of replication in empirical communication research

    Quality of life after sleeve gastrectomy and adjustable gastric banding

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    Abstract Background: With the addition of laparoscopic vertical sleeve gastrectomy (SG) to the bariatric surgery procedural toolkit, patients desiring a restrictive bariatric procedure often choose between adjustable gastric banding (LAGB) and SG. One study compared quality of life after these 2 procedures and found no difference. The purpose of our study was to re-evaluate the postoperative quality of life in LAGB and SG patients at a military teaching hospital in the United States. Methods: A retrospective review of 108 consecutive laparoscopic restrictive bariatric procedures performed within 15 months at a Department of Defense hospital was conducted. Of these 108 patients, 69 had undergone laparoscopic vertical SG and 39 LAGB. A validated quality of life questionnaire (Bariatric Quality of Life) was conducted a mean of 9.3 Ď® 3.2 months (range 5-16) postoperatively. The weight loss and standard laboratory parameters were measured at 0, 1, 3, 6, and 12 months. Results: The quality of life assessment revealed significantly better scores after SG than after LAGB (66.5 versus 57.9, P Ď­ .0002). The excess weight loss and excess body mass index loss at 3, 6, and 12 months postoperatively were significantly greater in the laparoscopic SG group. The patients demonstrated a clear preference over time for SG once it was offered. Conclusion: Early postoperative quality of life was superior after SG than after LAGB. SG also resulted in superior early excess weight loss. In a practice not constrained by reimbursement, these findings were associated with increased patient choice of SG after it began to be offered. (Surg Obes Relat Dis 2012;8:31-40.

    Increased heme-oxygenase 1 expression in mesenchymal stem cell-derived adipocytes decreases differentiation and lipid accumulation via upregulation of the canonical Wnt signaling cascade

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    Introduction: Heme oxygenase (HO), a major cytoprotective enzyme, attenuates oxidative stress and obesity. The canonical Wnt signaling cascade plays a pivotal role in the regulation of adipogenesis. The present study examined the interplay between HO-1and the Wnt canonical pathway in the modulation of adipogenesis in mesenchymal stem cell (MSC)-derived adipocytes. Methods: To verify the role of HO-1 in generating small healthy adipocytes, cobalt protoporphyrin (CoPP), inducer of HO-1, was used during adipocyte differentiation. Lipid accumulation was measured by Oil red O staining and lipid droplet size was measured by BODIPY staining. Results: During adipogenesis in vitro, differentiating pre-adipocytes display transient increases in the expression of genes involved in canonical Wnt signaling cascade. Increased levels of HO-1 expression and HO activity resulted in elevated levels of b-catenin, pGSK3b, Wnt10b, Pref-1, and shh along with increased levels of adiponectin (P \u3c 0.05). In addition, induction of HO-1 resulted in a reduction in C/EBPa, PPARg, Peg-1/Mest, aP2, CD36 expression and lipid accumulation (P \u3c 0.05). Suppression of HO-1 gene by siRNA decreased Wnt10b, pGSK3b and b-catenin expression, and increased lipid accumulation. The canonical Wnt responsive genes, IL-8 and SFRP1, were upregulated by CoPP and their expression was decreased by the concurrent administration of tin mesoporphyrin (SnMP), an inhibitor of HO activity. Furthermore, knockdown of Wnt10b gene expression by using siRNA showed increased lipid accumulation, and this effect was not decreased by concurrent treatment with CoPP. Also our results show that blocking the Wnt 10b antagonist, Dickkopf 1 (Dkk-1), by siRNA decreased lipid accumulation and this effect was further enhanced by concurrent administration of CoPP. Conclusions: This is the first study to demonstrate that HO-1 acts upstream of canonical Wnt signaling cascade and decreases lipogenesis and adipocyte differentiation suggesting that the HO-1 mediated increase in Wnt10b can modulate the adipocyte phenotype by regulating the transcriptional factors that play a role in adipogenesis. This is evidenced by a decrease in lipid accumulation and inflammatory cytokine levels, increased adiponectin levels and elevation of the expression of genes of the canonical Wnt signaling cascade

    Reproductive and Appetite Hormones and Bulimic Symptoms during Midlife

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    Eating disorders and related symptoms occur during midlife; however, little is known about their aetiology. It has been hypothesised that perimenopause represents a window of vulnerability for the development or exacerbation of eating disorder symptomatology because, like puberty, perimenopause is a period of reproductive hormone change. We compared symptoms of bulimia nervosa (bulimic symptomatology) assessed via mean scores on a self-report questionnaire in premenopausal and perimenopausal women. We also examined the association between hormone concentrations (reproductive/appetite) and bulimic symptomatology. No mean differences in bulimic symptomatology were observed between premenopause and perimenopause. However, there was a significant positive association between leptin and binge eating. Although no significant associations between reproductive hormones and bulimic symptomatology were observed, additional research is needed to provide definitive information. It is essential to learn more about the aetiology of eating disorders and related symptomatology across the lifespan in order to develop age-relevant treatment and prevention programs

    Movement ecology of a mobile predatory fish reveals limited habitat linkages within a temperate estuarine seascape

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    Large predatory fishes, capable of traveling great distances, can facilitate energy flow linkages among spatially separated habitat patches via extended foraging behaviors over expansive areas. Here, we tested this concept by tracking the movement of a large mobile estuarine fish, red drum (Sciaenops ocellatus). Specifically, we addressed the following two questions: (i) What are the spatial and temporal patterns of red drum movement (rates of dispersal) and activity space? (ii) Does red drum movement facilitate linkages among estuarine marsh complexes? Dispersal from the release location was greatest during the first 2 weeks at liberty before declining to less than 0.5 km·week–1 for the remainder of the study. Activity space initially increased rapidly before reaching an asymptote at 2.5 km2 2 weeks postrelease. Connectivity indices calculated among marsh complexes corroborated these observations, suggesting high residency and limited seascape-scale linkages via red drum movement behaviors. These data highlight potential within-estuary spatial structure for mobile fishes and could inform subsequent efforts to track energy flows in coastal food webs, predict the footprint of local habitat restoration benefits, and enhance the design of survey regimes to quantify overall population demography

    First Results from the Arcminute Cosmology Bolometer Array Receiver

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    We review the first science results from the Arcminute Cosmology Bolometer Array Receiver (ACBAR); a multifrequency millimeter-wave receiver optimized for observations of the Cosmic Microwave Background (CMB) and the Sunyaev-Zel'dovich (SZ) effect in clusters of galaxies. ACBAR was installed on the 2 m Viper telescope at the South Pole in January 2001 and the results presented here incorporate data through July 2002. We present the power spectrum of the CMB at 150 GHz over the range \ell = 150 - 3000 measured by ACBAR as well as estimates for the values of the cosmological parameters within the context of Lambda-CDM models. We find that the inclusion of Omega_Lambda greatly improves the fit to the power spectrum. We also observe a slight excess of small-scale anisotropy at 150 GHz; if interpreted as power from the SZ effect of unresolved clusters, the measured signal is consistent with CBI and BIMA within the context of the SZ power spectrum models tested.Comment: To be published in the proceedings of "The Cosmic Microwave Background and its Polarization", New Astronomy Reviews, (eds. S. Hanany and K.A. Olive). 10 pages, 2 figure

    Potential Added Value of Psychological Capital in Predicting Work Attitudes

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    Meeting the challenge of effectively managing human resources requires new thinking and approaches. To extend the traditional perspective of economic capital, increasing recognition is being given to human capital and more recently social capital, this article proposes and empirically tests the potential added value that psychological capital may have for employee attitudes of satisfaction and commitment. After first providing the background and theory of PsyCap, this article reports a study of manufacturing employees (N = 74) that found a significant relationship between PsyCap and job satisfaction (r=.373) and organization commitment (r=.313). Importantly, the employees’ PsyCap had a significant added impact over human and social capital on these work attitudes. Future research and practical implications conclude the article

    Quasars and their host galaxies

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    This review attempts to describe developments in the fields of quasar and quasar host galaxies in the past five. In this time period, the Sloan and 2dF quasar surveys have added several tens of thousands of quasars, with Sloan quasars being found to z>6. Obscured, or partially obscured quasars have begun to be found in significant numbers. Black hole mass estimates for quasars, and our confidence in them, have improved significantly, allowing a start on relating quasar properties such as radio jet power to fundamental parameters of the quasar such as black hole mass and accretion rate. Quasar host galaxy studies have allowed us to find and characterize the host galaxies of quasars to z>2. Despite these developments, many questions remain unresolved, in particular the origin of the close relationship between black hole mass and galaxy bulge mass/velocity dispersion seen in local galaxies.Comment: Review article, to appear in Astrophysics Update
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