Homeward Bound: Moving Treatment from the Institution to the Community

This study examined changes in the length of stay, cost savings, recidivism and community access when individuals with serious mental illness who were mandated into extended treatment were moved from a regional center institution to community treatment. Results showed significantly shorter length of stay, cost savings and no increase in recidivism when individuals were treated in the community program

Age-Related Changes in Perirhinal Cortex Sensitivity to Configuration and Part Familiarity and Connectivity to Visual Cortex

The perirhinal cortex (PRC) is a medial temporal lobe (MTL) structure known to be involved in assessing whether an object is familiar (i.e., meaningful) or novel. Recent evidence shows that the PRC is sensitive to the familiarity of both whole object configurations and their parts, and suggests the PRC may modulate part familiarity responses in V2. Here, using functional magnetic resonance imaging (fMRI), we investigated age-related decline in the PRC’s sensitivity to part/configuration familiarity and assessed its functional connectivity to visual cortex in young and older adults. Participants categorized peripherally presented silhouettes as familiar (“real-world”) or novel. Part/configuration familiarity was manipulated via three silhouette configurations: Familiar (parts/configurations familiar), Control Novel (parts/configurations novel), and Part-Rearranged Novel (parts familiar, configurations novel). “Real-world” judgments were less accurate than “novel” judgments, although accuracy did not differ between age groups. The fMRI data revealed differential neural activity, however: In young adults, a linear pattern of activation was observed in left hemisphere (LH) PRC, with Familiar > Control Novel > Part-Rearranged Novel. Older adults did not show this pattern, indicating age-related decline in the PRC’s sensitivity to part/configuration familiarity. A functional connectivity analysis revealed a significant coupling between the PRC and V2 in the LH in young adults only. Older adults showed a linear pattern of activation in the temporopolar cortex (TPC), but no evidence of TPC-V2 connectivity. This is the first study to demonstrate age-related decline in the PRC’s representations of part/configuration familiarity and its covariance with visual cortex

Diagnosis and Placement Variables Affecting the Outcome of Adolescents with Behavioral Disorders

The treatment of adolescents with behavior disorders represents significant challenges. This article reviews some of the most effective behavioral and pharmacological treatments identified in the research. The study used outcome data from a residential treatment program to identify variables that predicted level of functioning post-discharge. Significant variables included diagnosis (mood vs. behavior disorder spectrum), co-morbidity and discharge placement

Serum tumor necrosis factor-alpha concentrations are negatively correlated with serum 25(OH)D concentrations in healthy women

<p>Abstract</p> <p>Background</p> <p>Circulating 25 hydroxyvitamin D (25 (OH)D), an accurate measure of vitamin D status, is markedly greater in individuals with increased exposure to ultraviolet B (UVB) light via sunlight or the use of artificial UV light. Aside from the known relationship between vitamin D and bone, vitamin D has also been implicated in immune function and inflammation. Furthermore, a mass of evidence is accumulating that vitamin D deficiency could lead to immune malfunction. Our overall objective was to study the relationship between vitamin D status (as determined by serum 25(OH) D concentrations) and inflammatory markers in healthy women.</p> <p>Methods</p> <p>This observational study included 69 healthy women, age 25–82 years. Women with high UVB exposure and women with minimal UVB exposure were specifically recruited to obtain a wide-range of serum 25(OH)D concentrations. Health, sun exposure and habitual dietary intake information were obtained from all subjects. Body composition was determined by dual-energy-x-ray absorptiometry. A fasting blood sample was collected in the morning and analyzed for serum 25(OH)D, parathyroid hormone (iPTH), estradiol (E₂), cortisol, and inflammatory markers [tumor necrosis factor -alpha (TNF-α), interleukin-6 and -10 (IL-6, IL-10), and C-reactive protein (CRP)].</p> <p>Results</p> <p>Women with regular UVB exposure (Hi-D) had serum 25(OH)D concentrations that were significantly higher (<it>p </it>< 0.0001) and iPTH concentrations that were significantly lower (<it>p </it>< 0.0001) than women without regular UVB exposure (Lo-D). Although IL-6, IL-10, and CRP did not have a statistically significant relationship with 25(OH)D concentrations, linear regression models revealed a significant inverse relationship between serum 25(OH)D and TNF-α concentrations. This relationship remained significant after controlling for potential covariates such as body fat mass, menopausal status, age, or hormonal contraceptive use.</p> <p>Conclusion</p> <p>Serum 25(OH)D status is inversely related to TNF-α concentrations in healthy women, which may in part explain this vitamin's role in the prevention and treatment of inflammatory diseases. Results gleaned from this investigation also support the need to re-examine the biological basis for determining optimal vitamin D status.</p

Starting Well: Facilitating the Middle School Transition

School-based mental health programming is a viable intervention because it can provide evidenced-based-treatment (EBT) while avoiding the typical service barriers. In this study, 119 students (ages 10 to 12) were randomly assigned to participate in either a 24-session Coping Power Program (CPP) or a control group. Using the Behavior Assessment Scale for Children-2 (BASC-2), teachers reported significant improvements over time for all students (Attention Problems, Hyperactivity, Externalizing Problems, and Withdrawal, and Study Skills). However, teachers reported that students participating in the CPP showed significantly greater improvement than controls (Learning Problems, School Problems, Behavior Symptom Index, Social Skills, and Adaptive Skills). Effect sizes ranged from small (.19 for Withdrawal) to large (.76 for Adaptive Skills). Teacher reports showed greater improvement by the more experienced group leaders. Results validate the use of this EBT as a viable protocol. The improvement in both groups may suggest a spillover effect for untreated controls. The differential effect of group leader suggests that clinical experience may enhance EBT

DEMAND AND SUPPLY ASSESSMENT FOR THE MICHIGAN FROZEN POTATO INDUSTRY

This report presents a general assessment of the demand and supply conditions affecting the Michigan frozen potato industry. The information has been drawn from various secondary sources and interviews with key industry informants. The report is one of the major outputs of an ongoing study being prepared for the Michigan Potato Industry Commission and funded by the Michigan Agricultural Experiment Station. This analysis was necessitated by the 80% reduction in Michigan frozen processing potato acreage by Simplot in 1997. This reduction of 5,000 acres for the Grand Rapids processing facility has created both short-term and long-term concerns for the Michigan potato industry. This assessment provides broad background information relevant to determining why this cutback occurred and its likely impact if continued in the future. The report begins with a consideration of demand conditions, including both domestic and international demand trends for consumption and consumer preferences. The report then discusses supply issues, including current North American production capacity, international sourcing trends, competition from Canadian imports, cost considerations, processing innovation, and industry consolidation. The report concludes with a section addressing key strategic issues suggested by the demand and supply trends. NOTE: This staff paper contains text only. For charts and graphs (exhibits 1-17b) which have been omitted, contact Christopher Peterson at ([email protected]).Crop Production/Industries,