1,964 research outputs found
Wnt Signaling and the Polarity of the Primary Body Axis
How animals establish and pattern the primary body axis is one of the most fundamental problems in biology. Data from diverse deuterostomes (frog, fish, mouse, and amphioxus) and from planarians (protostomes) suggest that Wnt signaling through β-catenin controls posterior identity during body plan formation in most bilaterally symmetric animals. Wnt signaling also influences primary axis polarity of pre-bilaterian animals, indicating that an axial patterning role for Wnt signaling predates the evolution of bilaterally symmetric animals. The use of posterior Wnt signaling and anterior Wnt inhibition might be a unifying principle of body plan development in most animals.National Institutes of Health (U.S.) (R01GM080639)American Cancer Society (RSG-07-180-01-DDC)Rita Allen FoundationSearle Scholars ProgramSmith FoundationW. M. Keck Foundatio
Highly Stable, All-fiber, High Power ZBLAN Supercontinuum Source Reaching 4.75 µm used for Nanosecond mid-IR Spectroscopy
Contactless graphene conductance measurements: the effect of device fabrication on terahertz time-domain spectroscopy
340 nm pulsed UV LED system for europium-based time-resolved fluorescence detection of immunoassays
Mid-IR supercontinuum generation beyond 7 ÎĽm using a silica-fluoride-chalcogenide fiber cascade
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