34 research outputs found

    Ocean Literacy for All: A Tool Kit

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    This publication is made of two parts. The first part presents the history of oceanliteracy, and describes its framework made of 7 essential principles, and connectsthem to international ocean science programs that contributes to enhancing oceanknowledge and observations. Moreover, marine scientists and educators wereinterviewed to share their professional experiences on ocean literacy as well astheir views on its future. The last chapter of part 1 describes the existing challengesto marine education, as well as the path for the development of successful oceanliteracy activities in the context of the 2030 Agenda. One of the most importantfactors identified is related to the creation of multi-sector partnerships amongthe education, government, and private sector that have jointly built ocean literacyprograms for all formal educational levels from the primary school to the universitylevel as well as for non-formal learners. Worldwide examples of such programs arepresented.The second part, after introducing the methodological approach based on themulti-perspective framework for ESD developed by UNESCO, presents 14 activitiesthat could provide tested examples and support for the implementation of marineeducation initiatives. The aim is not to provide a one size-fits-all ready to usecollection, but rather to offer support and examples of what could be then adaptedfor different geographical and cultural contexts. The resources are designed to berelevant for all learners of all ages worldwide and to find their application in manylearning settings, while in their concrete implementation they will, naturally, haveto be adapted to the national or local context

    Experimental strategies for microRNA target identification

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    MicroRNAs (miRNAs) are important regulators of eukaryotic gene expression in most biological processes. They act by guiding the RNAi-induced silencing complex (RISC) to partially complementary sequences in target mRNAs to suppress gene expression by a combination of translation inhibition and mRNA decay. The commonly accepted mechanism of miRNA targeting in animals involves an interaction between the 5ā€²-end of the miRNA called the ā€˜seed regionā€™ and the 3ā€² untranslated region (3ā€²-UTR) of the mRNA. Many target prediction algorithms are based around such a model, though increasing evidence demonstrates that targeting can also be mediated through sites other than the 3ā€²-UTR and that seed region base pairing is not always required. The power and validity of such in silico data can be therefore hindered by the simplified rules used to represent targeting interactions. Experimentation is essential to identify genuine miRNA targets, however many experimental modalities exist and their limitations need to be understood. This review summarizes and critiques the existing experimental techniques for miRNA target identification

    Natures Enduring Patterns as a Path to Systems Literacy

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    Background and Year in Review Overview This conference marks the end of my time as president of ISSS. Ā It has been a busy and interesting year. Time to review and look forward.Ā Unfortunately, I was unable to be at the 2018 annual meeting at the beginning of my year as president as I had a minor stroke. However as fall began I recovered well and launched into my time as president with energy and enthusiasm. I began to implement a plan to explore Systems Literacy with ISSS members, to explore contributions of the ISSS Special Integration Groups (SIGs) by holding weekly video conferences online, applying digital technologies and to exploring the purpose and practices of the Society.Ā Connections with ISSS PartnersTurning to the organization of ISSS I will review the year and the actions I have taken on behalf of the organization. We renewed and reinforced our relationship with the American Association for the Advancement of Science (AAAS) and attended the Annual meeting in Washington DC in February 2019.I will report on our connections with International Council for Systems Engineering (INCOSE) and the several presentations ISSS members made at INCOSE in California in January 2019.Ā ISSS Members Management, Communications, Organization Development and Members WebsiteImplementation of a membership management system and website called myisss.org will be described. The SIG Sessions on Saturday have produced many new initiatives. By creating a program of meetings every Saturday online on a video conferencing system bluejeans we have begun to develop resources and understanding about each of the SIGs. The presentation will review the many surveys of members that have been completed including on the vision for system science, a request for suggestions for five-year action ideas for this society, opinions about annual conference location and developing models of relation between the SIGs and the relevance to ISSS society mission and purpose.Ā As a result of my stroke I began to explore natural patterns and pathologies concerned with the role of the brain in human experience. I will explore these biological models and their relevance for organizations. and touch on developments and personal experience in brain training.Ā Member education and learning through Saturday SIG SessionsI was curious to learn more about the nature and happenings of the Special Integration Groups and I developed a plan to showcase each SIG. Each Saturday morning and sometimes later in the evening to reach members in India, Australia and New Zealand. Over 74 members at one time or another joined the video conversation with a core group of about 20 participating every week. Each SIG Chair was offered the opportunity to summarize the activities of the SIG. A different SIG was featured each week. Recordings of the sessions are viewable by members at myisss.orgĀ This Years Conference ThemeTurning to the theme of the conference natures enduring patterns as a path to system literacy I will outline the work to date on systems literacy and identify the opportunities to develop systems literacy in the future.Ā Finally the presentation will give an outline of the conference in Corvallis in 2019 and introduce our plenary speakers and their relationship to systems approaches, natures enduring patterns, the ocean and to science education, and to the intent of this 2019 meeting to further develop approaches to systems literacy. I will also outline the hopes for the one hour workshop plenary session each day at the end of the morning and introduce the work of William Smith PhD who will assist me with these collaborative sessions to explore the relation between ISSS and Systems Literacy.Ā Ā Ā Ā Ā Ā Ā Ā Ā Ā Ā Next steps towards Systems LiteracyReflecting on my journey though life with an awareness of cybernetics and systems ideas I will encourage the continued co-development and research in both areas of inquiry and coordination between ISSS and the American Society for Cybernetics, INCOSE, IFSR, AAAS and Systems Dynamics Society.
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