Distinguishing Molecular Features and Clinical Characteristics of a Putative New Rhinovirus Species, Human Rhinovirus C (HRV C)

Background: Human rhinoviruses (HRVs) are the most frequently detected pathogens in acute respiratory tract infections (ARTIs) and yet little is known about the prevalence, recurrence, structure and clinical impact of individual members. During 2007, the complete coding sequences of six previously unknown and highly divergent HRV strains were reported. To catalogue the molecular and clinical features distinguishing the divergent HRV strains, we undertook, for the first time, in silico analyses of all available polyprotein sequences and performed retrospective reviews of the medical records of cases in which variants of the prototype strain, HRV-QPM, had been detected

'The Westphalian model and sovereign equality'

Although the Westphalian model takes many forms the association of Westphalian and sovereign equality is a prominent one. This article argues firstly that sovereign equality was not present as a normative principle at Westphalia. It argues further that while arguments for sovereign equality were present in the eighteenth century they did not rely on, or even suggest, a Westphalian provenance. It was, for good reasons, not until the late nineteenth century that the linkages of Westphalia and sovereign equality became commonplace, and even then sovereign equality and its linkage with Westphalia were disputed. It was not until after the Second World War, notably through the influential work of Leo Gross that the linkage of Westphalia and sovereign equality became not only widely accepted, but almost undisputed until quite recently. The article concludes by suggesting that not only did Gross bequeath a dubious historiography but that this historiography is an impediment to contemporary International Relations