20 research outputs found
Comparison of species specific bacterial qPCR and BACTEC blood culture for detection of pathogenic bacteria in blood samples amongst neonatal encephalopathy case infants.
<p>Comparison of species specific bacterial qPCR and BACTEC blood culture for detection of pathogenic bacteria in blood samples amongst neonatal encephalopathy case infants.</p
Results of blood culture, real-time PCR assays and sequencing of positives.
<p>Results of blood culture, real-time PCR assays and sequencing of positives.</p
Baseline demographic and clinical characteristics of mothers and babies.
a<p>chi-squared test.</p
Primer and probe target genes, sensitivities and sequences for the Real-Time PCR assays.
<p>Primer and probe target genes, sensitivities and sequences for the Real-Time PCR assays.</p
Study profile: Of the 427 participants screened, 425 were enrolled and started on ART at the three sites.
<p>Three hundred and twenty one participants completed their 12 months visit and had viral load results available at baseline and month 12. Forty nine had viral loads equal or above 1000 copies/ml and were genotyped. Of these 35 participants had HIV drug resistance mutations.</p
Summary of reasons for screen-outs and exclusion from analysis by site.
<p>Percentages shown as a proportion of either total screened (above), or total enrolled (below)</p><p>* Volunteers may be excluded for multiple reasons therefore columns may sum to >100%</p><p>** Systolic blood pressure >140 mm Hg and/or diastolic blood pressure >90 mm Hg</p><p>*** Including headaches, cough, fever, suspected and confirmed malaria</p><p>**** Active STI, including candidiasis, one possible HSV-1 infection, lower abdominal pain in women, and Bartholin's abscess</p>‡<p>Including suspected and confirmed TB, pneumonia</p>†<p>Includes 125/184 (67.9%) medical exclusions not linked to infectious disease (e.g., trauma, diabetes, cancer)</p>§<p>Includes 4/17 (23.5%) medical exclusions not linked to infectious disease (3 peripheral neuropathy and 1 inebriation at time of visit)</p
Map of study sites showing source populations, elevation (meters above sea level) and target enrolment.
<p>Map of study sites showing source populations, elevation (meters above sea level) and target enrolment.</p
Screened, enrolled and analyzed volunteers by site and gender.
<p>Screened, enrolled and analyzed volunteers by site and gender.</p
Equivalent numbers of men and women aged 18-60 were screened for this study.
<p>Among the 2,990 volunteers screened, 2,387 were enrolled, and a further 263 were excluded from analysis leaving a final study cohort of 2,124 volunteers.</p
Chemistry results, U.S.-based comparison intervals, and out of range (OOR) values
*<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0004401#pone.0004401-Kratz1" target="_blank">[22]</a></p>‡<p>The number and percent of African values outside the U.S.-based comparison interval</p>1<p>Excludes women from Kilifi</p>2<p>Excludes men from Masaka</p>3<p>Excludes all Masaka volunteers and males from KNH</p>4<p>No data available from KNH, Kangemi, Entebbe or Masaka</p