2,618 research outputs found
Probabilistic latent semantic analysis as a potential method for integrating spatial data concepts
In this paper we explore the use of Probabilistic Latent Semantic Analysis (PLSA) as a method for quantifying semantic differences between land cover classes. The results are promising, revealing ‘hidden’ or not easily discernible data concepts. PLSA provides a ‘bottom up’ approach to interoperability problems for users in the face of ‘top down’ solutions provided by formal ontologies. We note the potential for a meta-problem of how to interpret the concepts and the need for further research to reconcile the top-down and bottom-up approaches
Asymptotics of the Farey Fraction Spin Chain Free Energy at the Critical Point
We consider the Farey fraction spin chain in an external field . Using
ideas from dynamical systems and functional analysis, we show that the free
energy in the vicinity of the second-order phase transition is given,
exactly, by
Here is a reduced
temperature, so that the deviation from the critical point is scaled by the
Lyapunov exponent of the Gauss map, . It follows that
determines the amplitude of both the specific heat and susceptibility
singularities. To our knowledge, there is only one other microscopically
defined interacting model for which the free energy near a phase transition is
known as a function of two variables.
Our results confirm what was found previously with a cluster approximation,
and show that a clustering mechanism is in fact responsible for the transition.
However, the results disagree in part with a renormalisation group treatment
Estimating interactions and subgroup-specific treatment effects in meta-analysis without aggregation bias: A within-trial framework
Estimation of within-trial interactions in meta-analysis is crucial for reliable assessment of how treatment effects vary across participant subgroups. However, current methods have various limitations. Patients, clinicians and policy-makers need reliable estimates of treatment effects within specific covariate subgroups, on relative and absolute scales, in order to target treatments appropriately - which estimation of an interaction effect does not in itself provide. Also, the focus has been on covariates with only two subgroups, and may exclude relevant data if only a single subgroup is reported. Therefore, in this article we further develop the "within-trial" framework by providing practical methods to (1) estimate within-trial interactions across two or more subgroups; (2) estimate subgroup-specific ("floating") treatment effects that are compatible with the within-trial interactions and make maximum use of available data; and (3) clearly present this data using novel implementation of forest plots. We described the steps involved and apply the methods to two examples taken from previously published meta-analyses, and demonstrate a straightforward implementation in Stata based upon existing code for multivariate meta-analysis. We discuss how the within-trial framework and plots can be utilised with aggregate (or "published") source data, as well as with individual participant data, to effectively demonstrate how treatment effects differ across participant subgroups
SN 2005hj: Evidence for Two Classes of Normal-Bright SNe Ia and Implications for Cosmology
HET Optical spectra covering the evolution from about 6 days before to about
5 weeks after maximum light and the ROTSE-IIIb unfiltered light curve of the
"Branch-normal" Type Ia Supernova SN 2005hj are presented. The host galaxy
shows HII region lines at redshift of z=0.0574, which puts the peak unfiltered
absolute magnitude at a somewhat over-luminous -19.6. The spectra show weak and
narrow SiII lines, and for a period of at least 10 days beginning around
maximum light these profiles do not change in width or depth and they indicate
a constant expansion velocity of ~10,600 km/s. We analyzed the observations
based on detailed radiation dynamical models in the literature. Whereas delayed
detonation and deflagration models have been used to explain the majority of
SNe Ia, they do not predict a long velocity plateau in the SiII minimum with an
unvarying line profile. Pulsating delayed detonations and merger scenarios form
shell-like density structures with properties mostly related to the mass of the
shell, M_shell, and we discuss how these models may explain the observed SiII
line evolution; however, these models are based on spherical calculations and
other possibilities may exist. SN 2005hj is consistent with respect to the
onset, duration, and velocity of the plateau, the peak luminosity and, within
the uncertainties, with the intrinsic colors for models with M_shell=0.2 M_sun.
Our analysis suggests a distinct class of events hidden within the
Branch-normal SNe Ia. If the predicted relations between observables are
confirmed, they may provide a way to separate these two groups. We discuss the
implications of two distinct progenitor classes on cosmological studies
employing SNe Ia, including possible differences in the peak luminosity to
light curve width relation.Comment: ApJ accepted, 31 page
Halocarbon ozone depletion and global warming potentials
Concern over the global environmental consequences of fully halogenated chlorofluorocarbons (CFCs) has created a need to determine the potential impacts of other halogenated organic compounds on stratospheric ozone and climate. The CFCs, which do not contain an H atom, are not oxidized or photolyzed in the troposphere. These compounds are transported into the stratosphere where they decompose and can lead to chlorine catalyzed ozone depletion. The hydrochlorofluorocarbons (HCFCs or HFCs), in particular those proposed as substitutes for CFCs, contain at least one hydrogen atom in the molecule, which confers on these compounds a much greater sensitivity toward oxidation by hydroxyl radicals in the troposphere, resulting in much shorter atmospheric lifetimes than CFCs, and consequently lower potential for depleting ozone. The available information is reviewed which relates to the lifetime of these compounds (HCFCs and HFCs) in the troposphere, and up-to-date assessments are reported of the potential relative effects of CFCs, HCFCs, HFCs, and halons on stratospheric ozone and global climate (through 'greenhouse' global warming)
Research collaboration
AbstractThe complexity and cost of cardiovascular medical care dictate research to deliver high quality and cost-conscious cardiovascular care. This goal is aided by modeling medical decision making. To be useful, the modeling must be based on real data so that the results can serve as a guide to actual practice. It is suggested that a registry of randomized clinical trials and larger data bases in cardiovascular disease and health care delivery be established. The registry would be a resource for those desiring to model decision making. The registry would contain key words allowing retrieval by modelers accessing the registry and would contain contact information for consideration of possible collaborative work. The initiation of such a registry should contain plans for its evaluation to determine whether the registry itself is a cost-effective tool to encourage the needed research
Critical Behavior of the Meissner Transition in the Lattice London Superconductor
We carry out Monte Carlo simulations of the three dimensional (3D) lattice
London superconductor in zero applied magnetic field, making a detailed finite
size scaling analysis of the Meissner transition. We find that the magnetic
penetration length \lambda, and the correlation length \xi, scale as \lambda ~
\xi ~ |t|^{-\nu}, with \nu = 0.66 \pm 0.03, consistent with ordinary 3D XY
universality, \nu_XY ~ 2/3. Our results confirm the anomalous scaling dimension
of magnetic field correlations at T_c.Comment: 4 pages, 5 ps figure
Neutrino Mass and Oscillation
The question of neutrino mass is one of the major riddles in particle
physics. Recently, strong evidence that neutrinos have nonzero masses has been
found. While tiny, these masses could be large enough to contribute
significantly to the mass density of the universe. The evidence for
nonvanishing neutrino masses is based on the apparent observation of neutrino
oscillation -- the transformation of a neutrino of one type or "flavor" into
one of another. We explain the physics of neutrino oscillation, and review and
weigh the evidence that it actually occurs in nature. We also discuss the
constraints on neutrino mass from cosmology and from experiments with negative
results. After presenting illustrative neutrino mass spectra suggested by the
present data, we consider how near- and far-future experiments can further
illuminate the nature of neutrinos and their masses.Comment: 43 pages, 8 figures, to appear in the Annual Review of Nuclear and
Particle Science, Vol. 49 (1999
Use of multiple covariates in assessing treatment-effect modifiers: A methodological review of individual participant data meta-analyses
Individual participant data (IPD) meta-analyses of randomised trials are considered a reliable way to assess participant-level treatment effect modifiers but may not make the best use of the available data. Traditionally, effect modifiers are explored one covariate at a time, which gives rise to the possibility that evidence of treatment-covariate interaction may be due to confounding from a different, related covariate. We aimed to evaluate current practice when estimating treatment-covariate interactions in IPD meta-analysis, specifically focusing on involvement of additional covariates in the models. We reviewed 100 IPD meta-analyses of randomised trials, published between 2015 and 2020, that assessed at least one treatment-covariate interaction. We identified four approaches to handling additional covariates: (1) Single interaction model (unadjusted): No additional covariates included (57/100 IPD meta-analyses); (2) Single interaction model (adjusted): Adjustment for the main effect of at least one additional covariate (35/100); (3) Multiple interactions model: Adjustment for at least one two-way interaction between treatment and an additional covariate (3/100); and (4) Three-way interaction model: Three-way interaction formed between treatment, the additional covariate and the potential effect modifier (5/100). IPD is not being utilised to its fullest extent. In an exemplar dataset, we demonstrate how these approaches lead to different conclusions. Researchers should adjust for additional covariates when estimating interactions in IPD meta-analysis providing they adjust their main effects, which is already widely recommended. Further, they should consider whether more complex approaches could provide better information on who might benefit most from treatments, improving patient choice and treatment policy and practice
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