Comparison of combination intervention strategy (CIS) to standard of care (SOC) procedures.

<p>Comparison of combination intervention strategy (CIS) to standard of care (SOC) procedures.</p

Proportion of participants who achieved the primary outcome of linkage to HIV care within 1 month of HIV testing plus retention in HIV care at 12 months after HIV testing by study arm (combination intervention strategy [CIS] and standard of care [SOC]).

<p>Proportion of participants who achieved the primary outcome of linkage to HIV care within 1 month of HIV testing plus retention in HIV care at 12 months after HIV testing by study arm (combination intervention strategy [CIS] and standard of care [SOC]).</p

Primary and secondary outcomes for the combination intervention strategy (CIS) and standard of care (SOC) study arms.

<p>Primary and secondary outcomes for the combination intervention strategy (CIS) and standard of care (SOC) study arms.</p

Participant characteristics at HIV testing (<i>N</i> = 2,197).

<p>Participant characteristics at HIV testing (<i>N</i> = 2,197).</p

Characteristics of study participants, by data collection method.

<p>Characteristics of study participants, by data collection method.</p

Overall programme costs according to components intervention has beneficial effect on ((a) adherence on ART only (b) adherence on ART + discontinuation of ART (c) discontinuation of ART only (d) adherence on ART + risk of resistance (e) adherence on ART + discontinuation of ART + risk of resistance).

<p>Costs in US$m per 3 months (mean 2017–2036, discounted at 3$10 per year per person on ART.</p

Weighting of benefits and challenges of differentiated models of care¹.

<p>Weighting of benefits and challenges of differentiated models of care<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0196498#t002fn002" target="_blank">¹</a>.</p

Modelled intervention effects in individuals in whom adherence monitoring intervention is currently effective.

<p>In each case, this represents a large effect at the individual level—the overall effect of the intervention is then determined by the percent of people in whom the intervention is effective.</p

Outcomes of adherence interventions according to the components the intervention has an effect on, the percent of people the intervention is effective in and whether viral load monitoring is employed, all in the context of an intervention with a durable effect.

<p>Outcomes of adherence interventions according to the components the intervention has an effect on, the percent of people the intervention is effective in and whether viral load monitoring is employed, all in the context of an intervention with a durable effect.</p

Sensitivity analyses (a) in context of no viral load monitoring (b) in context of viral load monitoring.

<p>All in context of an intervention with a durable effect and the intervention being effective in 50% of people.</p