Identification of a conditionally essential heat shock protein in Escherichia coli

Protein D48.5 was recognized as a heat-inducible protein of Escherichia coli during the screening of a group of random, temperature-inducible Mud-Lac fusion mutants. Physiological and genetic analysis demonstrated that (i) the structural gene for this protein, designated htpI, is a member of the o32-dependent heat shock regulon, (ii) at 37[deg]C the synthesis of protein D48.5 is nearly constitutive, increasing slightly with growth rate in media of different composition, and (iii) this protein is essential for growth at high temperature.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/31386/1/0000299.pd

Hospitalized pneumococcal bacteremia incidence rates by year and age in rural Thailand, May 2005 to March 2010.

<p>Overall incidence 3.5 per 100,000 person-years, 95% CI (3.1, 4.1).</p

Clinical characteristics of patients with blood culture and hospitalized pneumococcal bacteremia cases in rural Thailand, May 2005–March 2010.

<p>Clinical characteristics of patients with blood culture and hospitalized pneumococcal bacteremia cases in rural Thailand, May 2005–March 2010.</p

Hospitalized pneumococcal bacteremia in 2 rural Thai provinces, May 2005-Mar 2010: a. Median monthly case counts, b. Median monthly case counts during four consecutive December-March vs. April-November periods^*.

<p>*p-values represent Wilcoxon Rank Sum Test comparisons.</p