(E)-3-Phenyl-2-(1-tosyl-1H-indol-3-ylcarbon­yl)acrylonitrile

In the title compound, C25H18N2O3S, the indole moiety is planar and makes a dihedral angle of 89.95 (09)° with the phenyl ring of the sulfonyl substituent. The mol­ecular conformation features a weak C—H⋯N short contact and the crystal packing reveals a weak C—H⋯O hydrogen bond

Crystal structure of 2-methylamino-3-nitro-4-p-tolylpyrano[3,2-c]chromen-5(4H)-one

The authors thank Dr Babu Varghese, SAIF, IIT, Chennai, India, for the data collection.Peer reviewedPublisher PD

rac-Diethyl 5-oxo-2-[(2,4,4-trimethyl­pentan-2-yl)amino]-4,5-dihydro­pyrano[3,2-c]chromene-3,4-dicarboxyl­ate

The title compound, C26H33NO7, comprises a racemic mixture of asymmetric mol­ecules containing one stereogenic centre. The dihedral angle between the mean planes of the fused pyran ring and the coumarin ring system is 8.12 (14)°. The mol­ecular structure features a short N—H⋯O contact, which generates an S(6) ring motif. The crystal packing are stabilized by C—H⋯O inter­actions

rac-Dimethyl 2-(tert-butyl­amino)-5-oxo-4,5-dihydro­pyrano[3,2-c]chromene-3,4-dicarboxyl­ate

The title compound, C20H21NO7, is asymmetric with a chiral centre located in the pyran ring and crystallizes as a racemate. The mol­ecular framework is somewhat bent; the coumarin moiety and the pyran ring are inclined by 7.85 (5)°. The mol­ecular structure is characterized by an intra­molecular N—H⋯O hydrogen bond, which generates an S(6) ring motif, and the crystal packing is stabilized by inter­molecular C—H⋯O hydrogen bonds. The 3-carboxyl­ate O atom is involved in both of them, having a bifurcated character

2-Iodo-3-(4-meth­oxy­anilino)-5,5-dimethyl­cyclo­hex-2-en-1-one

The cyclo­hexene ring in the title compound, C15H18INO2, adopts a sofa conformation. The dihedral angle between the cyclo­hexene (through all ring atoms) and benzene rings is 63.3 (1)°. The mol­ecular conformation features an N—H⋯I short contact and the crystal packing features C—H⋯O hydrogen bonds

5-(2-Hydroxy-5-methoxybenzoyl)-1-methyl-3-nitropyridin-2(1H)-one

In the title compound, C14H12N2O6, the dihedral angle between the benzene and pyridine rings is 65.90 (7)°. The nitro group is disordered and tilted with respect to the mean plane of the pyridine ring by 21.5 (4) and 22.8 (5)°, for the major and minor components, respectively. In the crystal, molecules are linked by O—H...N hydrogen bonds, forming chains propagating along [10-1]. The chains are linked by C—H...O hydrogen bonds, forming a three-dimensional framework. The crystal packing is further stabilized by offset π–π stacking interactions [intercentroid distance = 3.6291 (9) Å

Crystal structure of 4-(6-bromo-4-oxo-4H-chromen-3-yl)-2-methylamino-3-nitropyrano[3,2-c]chromen-5(4H)-one chloroform monosolvate

In the title compound, C22H13BrN2O7·CHCl3, the pyran ring adopts a shallow sofa conformation with the C atom bearing the bromochromene system as the flap [deviation = 0.291 (3) Å]. The dihedral angle between the pyran fused-ring system (all atoms; r.m.s. deviation = 0.032 Å) and the bromochromene ring system (r.m.s. deviation = 0.027 Å) is 87.56 (9)°. An intramolecular N—H...O hydrogen bond closes an S(6) ring. The Cl atoms of the solvent molecule are disordered over two sets of sites in a 0.515 (6):0.485 (6) ratio. In the crystal, inversion dimers linked by pairs of N—H...O hydrogen bonds generate R22(12) loops. The packing also features C—H...O and very weak π–π [centroid–centroid separation = 3.960 (2) Å] interactions, which link the dimers into a three-dimensional network

Crystal structure of (2-hydroxy-5-methylphenyl)(3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-5-yl)methanone

In the title compound, C21H17N3O2, the 2-hydroxy-5-methylphenyl ring and the phenyl ring are inclined to the mean plane of the pyrazolopyridine moiety (r.m.s. deviation = 0.013 Å) by 52.89 (9) and 19.63 (8)°, respectively, and to each other by 42.83 (11)°. In the molecule, there are intramolecular O—H...O and C—H...N hydrogen bonds, both enclosing an S(6) ring motif. In the crystal, molecules stack along the c-axis direction, forming columns within which there are a number of π–π interactions [the inter-centroid distances vary from 3.5278 (10) to 3.8625 (10) Å]. The columns are linked by C—H...π interactions, forming slabs parallel to (100)