Temporal and spatial constructs in service firms' internationalization patterns: The determinants of the accelerated growth of Emerging MNEs

AbstractThe recent years have witnessed an unprecedented surge of Emerging Multinational Enterprises (EMNEs), i.e. firms from the emerging economies that have started internationalization very late and have expanded abroad in a rather accelerated fashion.In particular, pace and international diversification emerge as distinctive features of service EMNEs' successful internationalization patterns, inducing scholars to question the applicability of traditional internationalization theories to EMNEs. The Linkage–Leverage–Learning (LLL) Model and the springboard perspective identified some of the critical EMNEs uniqueness and investigated potential antecedents of their abnormal patterns. Nevertheless, previous contributions neglected to provide a solid empirical base for measuring spatio-temporal dimensions of EMNEs' internationalization.This paper aims to empirically investigate the dimensions affecting the pace at which EMNEs enlarge their geographic scope, by performing OLS regression analysis.The main outcomes demonstrate the crucial role of cumulative benefits from inward internationalization and inter-regional diversification strategies in boosting EMNEs' overseas expansion, in opposition to traditional MNEs (TMNEs). The results corroborate some assumptions of emerging theories on EMNEs, and provide insight for extending traditional MNEs theories by rethinking concepts, relations and causalities

Imaging of Scarce Archaeological Remains Using Microwave Tomographic Depictions of Ground Penetrating Radar Data

The Romano-British site of Barcombe in East Sussex, England, has suffered heavy postdepositional attrition through reuse of the building materials for the effects of ploughing. A detailed GPR survey of the site was carried out in 2001, with results, achieved by usual radar data processing, published in 2002. The current paper reexamines the GPR data using microwave tomography approach, based on a linear inverse scattering model, and a 3D visualization that permits to improve the definition of the villa plan and reexamine the possibility of detecting earlier prehistoric remains

Pulse-duration dependence of the isotopic effect in simple molecular ions driven by strong laser fields

In this paper we discuss isotopic effects in simple molecular ions subjected to strong laser fields. We show that the intensity of the emitted spectra strongly depends upon both the nuclear mass of the molecular ions and the laser pulse duration. In particular, for short pulse duration [up to 8 optical cycles (o.c.)], we confirm the trend described in the most studied case in which the high-order harmonic generation is more efficient for heavier isotopes; in contrast, an interesting physical phenomenon is predicted for pulses longer than 16 o.c. characterized by an inverse effect in which lighter molecular species are responsible for higher-order harmonic emission

Capsule impaction presenting as acute small bowel perforation: a case series

INTRODUCTION: Perforation caused by capsule endoscopy impaction is extremely rare and, at present, only five cases of perforation from capsule endoscopy impaction are reported in the literature. CASE PRESENTATION: We report here two cases of patients with undiagnosed small bowel stenosis presenting with acute perforation after capsule endoscopy. Strictures in the small bowel were likely the inciting mechanism leading to acute small bowel obstruction and subsequent distension and perforation above the capsule in the area of maximal serosal tension. Case 1 was a 55-year-old Italian woman who underwent capsule endoscopy because of recurrent postprandial cramping pain and iron deficiency anemia, in the setting of negative imaging studies including an abdominal ultrasound, upper endoscopy, colonoscopy and small bowel follow-through radiograph. She developed a symptomatic bowel obstruction approximately 36 hours after ingestion of the capsule. Emergent surgery was performed to remove the capsule, which was impacted at a stenosis due to a previously undiagnosed ileal adenocarcinoma, leading to perforation. Case 2 was a 60-year-old Italian man with recurrent episodes of abdominal pain and diarrhea who underwent capsule endoscopy after conventional modalities, including comprehensive blood and stool studies, computed tomography, an abdominal ultrasound, upper endoscopy, colonoscopy, barium enema and small bowel follow-through, were not diagnostic. Our patient developed abdominal distension, acute periumbilical pain, fever and leukocytosis 20 hours after capsule ingestion. Emergent surgery was performed to remove the capsule, which was impacted at a previously undiagnosed ileal Crohn’s stricture, leading to perforation. CONCLUSIONS: The present report shows that, although the risk of acute complication is very low, the patient should be informed of the risks involved in capsule endoscopy, including the need for emergency surgical exploration

A Strategy analysis for genetic association studies with known inbreeding

Background: Association studies consist in identifying the genetic variants which are related to a specific disease through the use of statistical multiple hypothesis testing or segregation analysis in pedigrees. This type of studies has been very successful in the case of Mendelian monogenic disorders while it has been less successful in identifying genetic variants related to complex diseases where the insurgence depends on the interactions between different genes and the environment. The current technology allows to genotype more than a million of markers and this number has been rapidly increasing in the last years with the imputation based on templates sets and whole genome sequencing. This type of data introduces a great amount of noise in the statistical analysis and usually requires a great number of samples. Current methods seldom take into account gene-gene and gene-environment interactions which are fundamental especially in complex diseases. In this paper we propose to use a non-parametric additive model to detect the genetic variants related to diseases which accounts for interactions of unknown order. Although this is not new to the current literature, we show that in an isolated population, where the most related subjects share also most of their genetic code, the use of additive models may be improved if the available genealogical tree is taken into account. Specifically, we form a sample of cases and controls with the highest inbreeding by means of the Hungarian method, and estimate the set of genes/environmental variables, associated with the disease, by means of Random Forest. Results: We have evidence, from statistical theory, simulations and two applications, that we build a suitable procedure to eliminate stratification between cases and controls and that it also has enough precision in identifying genetic variants responsible for a disease. This procedure has been successfully used for the betathalassemia, which is a well known Mendelian disease, and also to the common asthma where we have identified candidate genes that underlie to the susceptibility of the asthma. Some of such candidate genes have been also found related to common asthma in the current literature. Conclusions: The data analysis approach, based on selecting the most related cases and controls along with the Random Forest model, is a powerful tool for detecting genetic variants associated to a disease in isolated populations. Moreover, this method provides also a prediction model that has accuracy in estimating the unknown disease status and that can be generally used to build kit tests for a wide class of Mendelian diseases

Laser induced ultrafast H2+ dinamic and attosecond generation

We examine the possibility that a H2+ molecular ion driven by a linearly polarized laser field can be considered as a source of attosecond pulses. The emisseion is investigated taking into account the role of the internuclear distance and by changing the angle between the laser field and the molecular axis. We find that the attosecond pulses emission happens when the electron cloud is over one nucleus; on the contrary, when the elctron is travelling between the two nuclei the attosecond emission do not take place

Angular harmonic dependence from a 3D-H2+ Molecular Ion

The time-dependent Schroedinger equation of a H2+ molecular ion in the presence of a linearly polarized laser field is numerically solved by means of a split-operator parallel code. The electron, driven by the laser electric field, emits electromagnetic radiation whose HHG spectrum (shown in Figure 1) can be finely controlled by changing the angle between the laser electric field and the molecular axis. The numerical results confirm that the structure of the spectra strongly depends on this angle. In particular the correlation between the laser orientation (with respect to the molecular axis) and the intensity of various harmonic peaks are displayed in Figure 2

EFFECT OF WIND LOADS ON NON REGULARLY SHAPED HIGH-RISE BUILDINGS

Wind loads have historically been recognized as one of the most important issue in high-rise buildings analysis and design. In particular, in regions of low seismic intensity, a high-rise building lateral design is controlled by wind loads. In wind analysis, Computational Fluid Dynamics (CFD) and/or wind tunnel testing are required to calculate the external pressures acting on a building. In this paper, two case studies are presented to show how the wind loads are calculated and applied in design. The first case study is based on the CFD results for the New Marina Casablanca Tower in Casablanca, Morocco. The second case study considers the results from the wind tunnel test studies conducted for the Al- Hamra tower, in Kuwait City, Kuwait. The New Marina Casablanca tower is a 167m tall concrete building, with a unique twisting shape generated from the relative rotation of two adjacent floors. Sloped columns are introduced in the perimeter to follow the tower outer geometry and to support the concrete slabs spanning between the central core and the perimeter frame. The effects of wind loads on the twisted geometry has been studied in details since the pressure coefficients are not easily identified for such a complex form. In addition, the effect of the wind loads on the structure presented unique challenges that required innovative structural solutions. The Al-Hamra tower is a 412m tall concrete building with a sculpted twisting form which optimizes the views to the Arabian Gulf while minimizing the solar heat gain. The complex form is realized using sloped walls and vertical columns on the perimeter and a central concrete core. The unique shape of the tower presented several design challenges related to the wind loads on the structure. This paper will discuss the unique challenges and solutions associated with wind loads effect on buildings of unique form

Confocal Laser Endomicroscopy in the Study of Colonic Mucosa in IBD Patients: A Review

Confocal laser endomicroscopy (CLE) is one of several novel methods that provide real-time, high-resolution imaging at a micronscale via endoscopes. CLE and related technologies are often termed “virtual biopsy” as they simulate the images seen in traditional histology. Recently, the use of CLE was reported in the study of colonic mucosa in patients with inflammatory bowel diseases and in particular in patients affected by ulcerative colitis. CLE has the potential to have an important role in management of IBD patients as it can be used to assess the grading of colitis and in detection of microscopic colitis in endoscopically silent segments. Moreover, CLE can be used in surveillance programs especially in high-risk patients. This report aims to evaluate the current data on the application of confocal endomicroscopy in clinical gastroenterology and particularly in the study of colonic mucosa in UC patients