Effect of genetic background and postinfectious stress on visceral sensitivity in Citrobacter rodentium-infected mice

Infectious gastroenteritis is a major risk factor to develop postinfectious irritable bowel syndrome (PI-IBS). It remains unknown why only a subgroup of infected individuals develops PI-IBS. We hypothesize that immunogenetic predisposition is an important risk factor. Hence, we studied the effect of Citrobacter rodentium infection on visceral sensitivity in Th1-predominant C57BL/6 and Th2-predominant Balb/c mice.status: publishe

Staphylococcal enterotoxin B triggers a bystander immune response to food antigens leading to visceral hypersensitivity

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Evidence for TRP channel sensitization in IBS with histamine 1 receptor antagonism as effective treatment

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Upregulation of mast cell related genes in Irritable Bowel Syndrome.

Poster presentationstatus: Published onlin

Neuronal sensitization of TRPV1 by histamine mediated by histamine 1 receptor in an unique cohort of PI-IBS patients

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Food Antigen-specific Sensitization of Nociceptive Nerves as an Underlying Mechanism of Visceral Pain in IBS

Oral presentationstatus: publishe