287 research outputs found

    Studies of Corrosion Resistance of Passive Layers on Al-Ni Alloys in the Presence of Chloride Ions

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    The corrosion resistance of passive layers was studied on cast Al-Ni alloys with an ever-increasing mass content of nickel (Ā«;(Ni) = 0.54 - 4.30%). The method of potentiodynamic polarization, measuring to 10 V, the method of measuring the changes of the current at a constant potential of 0 V, and the method of determining the critical concentrations of chloride ion gave identical dependence of the corrosive resistance of the passive layers on the mass content of nickel in the alloy. The method of potentiodynamic polarization at low potentials to 1 V was applied to obtain the dependence of insulating properties of the passive layers on the mass content of nickel in alloy

    On implementation of a nonlinear four node shell finite element for thin multilayered elastic shells

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    A simple non-linear stress resultant four node shell finite element is presented. The underlying shell theory is developed from the three dimensional continuum theory via standard assumptions on the displacement field. A model for thin shells is obtained by approximating terms describing the shell geometry. In this work the rotation of the shell director is parameterized by the two Euler angles, although other approaches can be easily accomodated. A procedure is provided to extend the presented approach by including the through-thickness variable material properties. These may include a general non-linear elastic material with varied degree of orthotropy, which is typical for fibre reinforced composites. Thus a simple and efficient model suitable for analysis of multilayered composite shells is attained. Shell kinematics is consistently linearized, leading to the Newton-Raphson numerical procedure, which preserves quadratic rate of asymptotic convergence. A range of linear and non-linear tests is provided and compared with available solutions to illustrate the approach

    Integrierte Seminararbeiten als Ergebnis des Projektunterrichts

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    Polazeći od teorije viÅ”estrukih inteligencija Howarda Gardnera te projektne nastave Johna Deweya, u radu se izlažu učinci podučavanja učenika tehnikom pisanja znanstvenog rada. Format u kome se učenici pismeno izražavaju jest seminarski rad, koncipiran prema modelu integrirane nastave u srednjoj muzičkoj Å”koli. U nju su uključeni predmeti Teorija muzike, Istorija muzike s upoznavanjem muzičke literature, Nacionalna istorija muzike te Srpski jezik i književnost. Mogućnosti koje pruža takav pristup viÅ”estruke su i odnose se na: stjecanje učeničkih vjeÅ”tina u domeni akademskog pisanja prije odlaska na fakultet, Å”to svakako standardi vezani s pisanjem eseja, stručnog teksta i rezimea drugih tekstova zahtijevaju; unapređivanje Å”kolske klime, etosa i među učenicima i među profesorima uključenima u proces. Broj predmeta koji se mogu uključiti u određenu temu nije ograničen i tiče se podjednako užestručnih, glazbenih i općeobrazovnih. Posebno je značajno nadilaženje neusklađenosti programa različitih predmeta u kurikulu pri izradi seminarskih radova, putem anticipiranja teme (za gradivo koje će se iz pojedinih predmeta raditi kasnije) ili utvrđivanja gradiva. Format blok-nastave u obliku okruglog stola za učenike različitih razreda, u tako koncipiranom podučavanju, omogućava učenicima razmjenu iskustava, vrÅ”njačku edukaciju i jačanje kritičarskih sposobnosti učenika. Takva Å”kolska praksa proistekla je i iz dugogodiÅ”njeg rada tima za integriranu nastavu Muzičke Å”kole ā€žDr. Miloje Milojevićā€œ iz Kragujevca i iz potrebe da koordinatori nastave svoja znanja stečena na doktorskim studijama muzikologije i srpskog jezika i književnosti te samostalnim znanstvenim radom prilagode i prenesu učenicimaStarting with Howard Gardnerā€™s theory of multiple intelligences and John Deweyā€™s project teaching, the paper exposes the effects of teaching students by means of the technique of writing scientific papers. The format of studentsā€™ expressing themselves in a written form is a seminar paper, outlined according to the integrated teaching model in music school. This comparative and aesthetic approach of writing studentsā€™ papers encompasses the subjects of Music theory, History of music, National history of music and the Serbian language and literature. The possibilities provided by such an approach are multiple and relate to: acquiring studentsā€™ skills in the domain of academic writing before entering a university, and which is certainly required by standards related to writing essays, vocational texts and summaries of other texts; enhancing school climate, ethos, not only among students, but also among teachers included in the process. The number of subjects whose content can be interconnected in a specific topic is not limited, and it equally relates to narrower vocational, music and general education subjects. The outcomes of this method of work are focused on the most possible functional meeting demands, which each subject individually brings along. What is particularly important is the overcoming curriculum incompatibilities of different subjects when writing seminar papers, by means of anticipating the subject or by revising material. The block teaching format in the form of round table for students of various grades, in such conceived teaching, enables studentsā€™ exchange of experiences, peer education and strengthening of studentsā€™ critical abilities. Such school practice comes, not only from long-standing work of Integrated teaching team of music school ā€œDr Miloje Milojevićā€ in Kragujevac, but also from the need of coordinators of the teaching process to adapt and transfer knowledge acquired during doctoral studies of musicology to students.Von der Theorie multipler Intelligenzen von Howard Gardner und des Projektunterrichts von John Dewey ausgehend, werden in der Arbeit Auswirkungen der Belehrung der SchĆ¼ler durch die Technik des Verfassens wissenschaftlicher Arbeit prƤsentiert. Das Format der schriftlichen ƄuƟerung der SchĆ¼ler ist die Seminararbeit, die nach dem Modell des integrierten Unterrichts in der Musikschule konzipiert ist. Solcher Unterricht umfasst die folgenden FƤcher: Musiktheorie, Musikgeschichte und Kennenlernen der Musikliteratur, nationale Musikgeschichte und serbische Sprache und Literatur. Dieser Ansatz bietet vielfƤltige Mƶglichkeiten und zwar erwerben die SchĆ¼ler hierbei Fertigkeiten im Bereich des Verfassens akademischer Texte bereits vor dem Studium, nƤmlich Fertigkeiten, die beim Verfassen von Essays, Zusammenfassungen und Fachtexten zum Standard gehƶren. Ferner trƤgt dieser Ansatz zur Verbesserung des Schulklimas unter SchĆ¼lern und unter Lehrern bei. Die Anzahl der FƤcher, die in ein bestimmtes Thema einbezogen werden kƶnnen, ist nicht begrenzt und betrifft gleichermaƟen eng fachorientierte und allgemeinausbildende FƤcher, sowie FƤcher im Bereich Musik. Besonders bedeutend ist es dabei die mangelnde Ɯbereinstimmung der Programme unterschiedlicher FƤcher im Lehrplan zu Ć¼berbrĆ¼cken und beim Verfassen der Seminararbeiten bestimmte Themen zu antizipieren (wenn die Lerninhalte in bestimmten FƤchern erst spƤter behandelt werden) oder den Lernstoff zu wiederholen und zu festigen. Eine derartig konzipierte Belehrung ermƶglicht den SchĆ¼lern verschiedener Klassen in den Doppelstunden und im Format der runden Tische Erfahrungen auszutauschen, fĆ¼hrt zum kollegialen Lernen und zur StƤrkung der kritischen FƤhigkeiten der SchĆ¼ler. Die hier beschriebene Schulpraxis entstammt der langjƤhrigen Arbeit des Teams fĆ¼r integrierten Unterricht der ā€žDr. Miloje Milojevićā€œ Musikschule aus Kragujevac und ist Folge des Bedarfs von Koordinatoren, ihre an Doktorstudien der Musikologie und der serbischen Sprache und Literatur erworbenen Kenntnisse durch eigenstƤndige wissenschaftliche Arbeit anzupassen und den SchĆ¼lern zu vermitteln

    MAGE-A3/4 and NY-ESO-1 antigens expression in metastatic esophageal squamous cell carcinoma

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    In the present study we analyzed immunohistochemical expression of MAGE-A 3/4 and NY-ESO-1 in 55 samples of esophageal squamous cell carcinomas (ESCC) and their respective lymph node metastases. To our knowledge this is the first study to assess and compare the expression of these antigens in ESCC lymph node metastases

    Antimicrobial growth promoters in feed - possibilities and necessity

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    The attention of the scientific and professional communities, as well as of food consumers, has always been directed towards finding adequate nutritional strategies that could improve food production and safety. By using antibiotics as feed additives, farmers gained increased profits based on higher growth rates with better feed conversion and lower costs of therapeutic treatment. The quantities of antibiotics used as growth promoters for farm animals have been increasing constantly, but at the same time, the frequency of bacterial resistance to antibiotics and the presence of antibiotic residues in food have become a global problem. To eliminate or minimize these risks, on 1 January 2006, antibiotics were banned from use as additives in animal nutrition in the European Union. Accordingly, there is interest in developing new nutritional strategies that would support the function of the autochthonous microbiota in the animal gastrointestinal tract to control pathogenic bacteria. Probiotics, prebiotics, phytobiotics and feed enzymes are a new generation of growth promoters and largely achieve their effects by using the physiological mechanisms of animals and/or their intestinal microbiomes, enabling animals to completely fulfil their genetic potential with respect to production properties

    The Effect of Liquid-Phase Exfoliated Graphene Film on Neurodifferentiation of Stem Cells from Apical Papilla

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    Background: Dental stem cells, which originate from the neural crest, due to their easy accessibility might be good candidates in neuro-regenerative procedures, along with graphene-based nanomaterials shown to promote neurogenesis in vitro. We aimed to explore the potential of liquid-phase exfoliated graphene (LPEG) film to stimulate the neuro-differentiation of stem cells from apical papilla (SCAP). Methods: The experimental procedure was structured as follows: (1) fabrication of graphene film; (2) isolation, cultivation and SCAP stemness characterization by flowcytometry, multilineage differentiation (osteo, chondro and adipo) and quantitative PCR (qPCR); (3) SCAP neuro-induction by cultivation on polyethylene terephthalate (PET) coated with graphene film; (4) evaluation of neural differentiation by means of several microscopy techniques (light, confocal, atomic force and scanning electron microscopy), followed by neural marker gene expression analysis using qPCR. Results: SCAP demonstrated exceptional stemness, as judged by mesenchymal markersā€™ expression (CD73, CD90 and CD105), and by multilineage differentiation capacity (osteo, chondro and adipo-differentiation). Neuro-induction of SCAP grown on PET coated with graphene film resulted in neuron-like cellular phenotype observed under different microscopes. This was corroborated by the high gene expression of all examined key neuronal markers (Ngn2, NF-M, Nestin, MAP2, MASH1). Conclusions: The ability of SCAPs to differentiate toward neural lineages was markedly enhanced by graphene film
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