9,581 research outputs found

    Interior noise in military helicopters

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    The Temporary Threshold Shift (TTS) or temporary hearing loss caused by excessive interior noise in military helicopters results in a critical degradation of the acoustically unprotected infantryman\u27s ability to detect the existence or the approach of the enemy by hearing under combat conditions. The overall problem of noise reduction in helicopters consists of: (1) identifying the various noise sources, and (2) employing appropriate noise control techniques. Identification of the source is accomplished by the frequency correlation of 1/10-octave band analysis of the interior sound levels measured within the helicopter cabin with near-field sound generated by the sound sources. Reduction of the overall interior helicopter noise can be accomplished by attenuation or interdiction along the noise \u27\u27path , and/or by redesign of the source to reduce the sound generated in the first place. In the case of the helicopter, attenuation or interdiction of the noise consists of: (1) padding or insulating the source with lightweight absorption materials, (2) vibration isolation of the source, and/or (3) the wearing of ear protection by the passengers. This study proposes the installation of lightweight leaded vinyl sheet as an interior measure until redesign can be accomplished to permit adequate vibration isolation. Ear protection is recommended for all crew and passengers, but it is realized that cost and storage space may be prohibitive --Abstract, page ii

    Characterization of the ZFX family of transcription factors that bind downstream of the start site of CpG island promoters

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    Our study focuses on a family of ubiquitously expressed human C₂H₂ zinc finger proteins comprised of ZFX, ZFY and ZNF711. Although their protein structure suggests that ZFX, ZFY and ZNF711 are transcriptional regulators, the mechanisms by which they influence transcription have not yet been elucidated. We used CRISPR-mediated deletion to create bi-allelic knockouts of ZFX and/or ZNF711 in female HEK293T cells (which naturally lack ZFY). We found that loss of either ZFX or ZNF711 reduced cell growth and that the double knockout cells have major defects in proliferation. RNA-seq analysis revealed that thousands of genes showed altered expression in the double knockout clones, suggesting that these TFs are critical regulators of the transcriptome. To gain insight into how these TFs regulate transcription, we created mutant ZFX proteins and analyzed them for DNA binding and transactivation capability. We found that zinc fingers 11–13 are necessary and sufficient for DNA binding and, in combination with the N terminal region, constitute a functional transactivator. Our functional analyses of the ZFX family provides important new insights into transcriptional regulation in human cells by members of the large, but under-studied family of C₂H₂ zinc finger proteins

    Efficient Operations On MDDs For Building Constraint Programming Models

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    International audienceWe propose improved algorithms for defining the most common operations on Multi-Valued Decision Diagrams (MDDs): creation, reduction, complement , intersection, union, difference, symmetric difference, complement of union and complement of intersection. Then, we show that with these algorithms and thanks to the recent development of an efficient algorithm establishing arc consistency for MDD based constraints (MDD4R), we can simply solve some problems by modeling them as a set of operations between MDDs. We apply our approach to the regular constraint and obtain competitive results with dedicated algorithms. We also experiment our technique on a large scale problem: the phrase generation problem and we show that our approach gives equivalent results to those of a specific algorithm computing a complex automaton

    Electronic Construction Collaboration System – Final Phase

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    This phase of the research project involved two major efforts: (1) Complete the implementation of AEC-Sync (formerly known as Attolist) on the Iowa Falls Arch Bridge project and (2) develop a web-based project management system (WPMS) for projects under $10 million. For the first major effort, AEC-Sync was provided for the Iowa Department of Transportation (DOT) in a software as a service agreement, allowing the Iowa DOT to rapidly implement the solution with modest effort. During the 2010 fiscal year, the research team was able to help with the implementation process for the solution. The research team also collected feedback from the Broadway Viaduct project team members before the start of the project and implementation of the solution. For the 2011 fiscal year, the research team collected the post-project surveys from the Broadway Viaduct project members and compared them to the pre-project survey results. The result of the AEC-Sync implementation in the Broadway Viaduct project was a positive one. The project members were satisfied with the performance of AEC-Sync and how it facilitated document management and transparency. In addition, the research team distributed, collected, and analyzed the pre-project surveys for the Iowa Falls Arch Bridge project. During the 2012 fiscal year, the research team analyzed the post-project surveys for the Iowa Falls Arch Bridge project AEC-Sync implementation and found a positive outcome when compared to the pre-project surveys. The second major effort for this project involved the identification and implementation of a WPMS solution for smaller bridge and highway projects. During the 2011 fiscal year, Microsoft SharePoint was selected to be implemented on these smaller highway projects. In this year, workflows for the shop/working drawings for the smaller highway projects specified in Section 1105 of the Iowa DOT Specifications were developed. These workflows will serve as the guide for the development of the SharePoint pages. In order to implement the Microsoft SharePoint pages, the effort of an integrated team proved to be vital because it brought together the expertise required from researchers, programmers, and webpage developers to develop the SharePoint pages

    Continuous coprocessing of biomass with waste plastic by fast and catalytic pyrolysis

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    Evaluación de las condiciones de almacenamiento y transporte de material estéril por profesional enfermero - hospital público, Chiclayo 2021

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    La presente investigación de tipo cuantitativo descriptivo, tuvo como objetivo determinar el nivel de cumplimiento de las condiciones de almacenamiento y transporte del material estéril por profesional enfermero del servicio Anestesiología y Centro Quirúrgico del Hospital Regional Lambayeque, se consideró una muestra censal puesto que la población estuvo constituida por 23 enfermeros, para la recolección de los datos se empleó como técnica la encuesta y como instrumento el cuestionario, con un total de 33 ítems, dividido en cuatro aspectos: almacén, estantes, manipulación y transporte de material estéril; elaborado por el investigador, validado por juicio de expertos, obteniendo un coeficiente V de Aiken de 0,8; y una confiabilidad de 0,85 de acuerdo al alfa de Crombach. El procesamiento de información se realizó en Microsoft Excel, y para el análisis se utilizó la estadística descriptiva; su interpretación se realizó después de ser presentado en tablas de frecuencias absolutas y porcentajes por cada aspecto establecido en el cuestionario. Los resultados mostraron que el profesional enfermero realiza el almacenamiento y transporte del material estéril con un nivel de cumplimiento Medio, con un puntaje de 46 ( 1.4), representado por el 47.8 % que cumple siempre con las condiciones. Basado en los principios bioéticos de Elio Sgreccia: Principio de libertad y responsabilidad, sociabilidad y subsidiaridad. Con base en ello se puede concluir que existe un riesgo de que el material estéril que circula en centro quirúrgico no está siendo adecuadamente manipulado ni almacenado y por consiguiente no se garantizaría el tiempo de vida útil
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