Constructing a Test Bank for Information Science based upon Bloom's principles

This paper outlines an approach to creating questions for a subject-based question bank for use in UK library schools. The authors outline a concept map for information science and describe how Bloom’s taxonomy can be adapted to the creation of higher level questions than the commonly used and simple recall type. Sample questions were created using the International Encyclopedia of Information and Library Science (IEILS) and subjects defined by staff at the Department of Information Science at Loughborough University. A role is suggested for the Learning and Teaching Support Network for Information and Computer Science (LTSN-ICS)

Capillary-leak syndrome: an unrecognized early immune adverse effect of checkpoint-inhibitors treatment

Capillary-leak syndrome is strongly associated with cytokine activity states. It is an ill-recognized adverse effect of checkpoint inhibitors treatment, which are typically associated with cellular immune response. We describe two patients with capillary leak syndrome following immune checkpoint inhibitors treatment. We present linking mechanisms between checkpoint inhibitors, cellular immunity, cytokine action and endothelial damage. We suggest that capillary-leak syndrome is a unique adverse effect of immunotherapy, resulting from complex interactions between cellular and cytokine activation and that its expression is probably depending on inherent host immune variabilities. </jats:p