31 research outputs found
Molecular characterization of African swine fever virus from domestic pigs in northern Tanzania during an outbreak in 2013
Sero-prevalence and risk factors associated with African swine fever on pig farms in southwest Nigeria
Characterization of Self-Processing Activities and Substrate Specificities of Porcine Torovirus 3C-Like Protease
Interstitial nephritis of unknown aetiology in captive slender‐horned gazelles ( Gazella leptoceros
Four captive slender-horned gazelles (Gazella leptoceros) died in a short period. The clinical signs were lethargy progressing rapidly to stupor and death. Differential diagnoses included trauma, intoxication, hepatic and renal failure. Blood analyses revealed increased blood urea nitrogen, creatinine, aspartate aminotransferase, alanine aminotransferase and creatine kinase. Serum mean copper levels had risen almost two-fold. No trauma was found and salient post-mortem examination results were friable livers and granular and/or pitted renal capsular surfaces with indentations. The most consistent histological change was chronic interstitial lymphoplasmacytic nephritis, tubular degeneration and glomerulosclerosis. Potential causes were investigated and ruled out. Erysipelothrix rhusiopathiae was cultured from the liver and the kidney of three animals, but could not be confirmed histopathologically. Polymerase chain reaction (PCR) carried out on kidney and liver and serological screening were negative for leptospirosis. Copper involvement could not be confirmed by toxicological analysis of liver and kidney tissue or by histopathology. The aetiology remains unknown