Acute effects of reducing sitting time in adolescents: a randomized cross-over study

BACKGROUND: Levels of sitting among adolescents are high, especially during the school day. The acute cognitive and health consequences associated with prolonged sitting are poorly understood in adolescents. This randomized crossover design study examined the acute effects of a simulated school day with reduced sitting or usual sitting on adolescents\u27 cognitive function and cardiometabolic biomarkers. METHODS: Eighteen healthy school aged adolescents were recruited from the community to the study (11 males; 7 females; mean age [SD]&nbsp;=&nbsp;13.5&nbsp;&plusmn;&nbsp;0.9&nbsp;years). Two protocols were developed to simulate an adolescent school day, the amount of time spent sitting was manipulated reflecting: a \u27typical\u27 day (65% of the time spent sitting with two sitting bouts sitting &gt;20&nbsp;min) and a \u27reduced sitting\u27 day (adolescents sat for 50% less time with no bouts of sitting &gt;20 mins). The order that participants were exposed to each condition was randomized (via random number generator). Participants were not fully blinded as they could observe the difference between conditions. Energy intake and moderate to vigorous physical activity (MVPA) were standardized for both conditions and monitored for 48&nbsp;h post-condition for compensatory effects. Cognitive (working memory) and cardiometabolic outcomes (lipids, glucose, insulin, IL-6, apo-A1, apo-B, blood pressure,) were assessed pre and post for both conditions, BMI and body fat were assessed on the morning of the intervention. Data were analyzed using linear mixed models. Standardised effect sizes were calculated. RESULTS: Compared with the typical school day, the reduced sitting day demonstrated significant positive effects for apoB/apoA-1 ratio (adjusted difference&nbsp;&plusmn;&nbsp;SD) -0.02&nbsp;&plusmn;&nbsp;0.03; P&nbsp;=&nbsp;0.03; effect size [Cohen\u27s d]&nbsp;=&nbsp;-0.67. Findings for total cholesterol -0.19&nbsp;&plusmn;&nbsp;0.27; P&nbsp;=&nbsp;0.28; d&nbsp;=&nbsp;-0.71; HDL cholesterol -0.23&nbsp;&plusmn;&nbsp;0.50; P&nbsp;=&nbsp;0.12 d&nbsp;=&nbsp;-0.66; and total cholesterol/HDL ratio 0.25&nbsp;&plusmn;&nbsp;0.53; P&nbsp;=&nbsp;0.25; d&nbsp;=&nbsp;0.51 and for cognition 0.64&nbsp;&plusmn;&nbsp;0.15; P&nbsp;=&nbsp;0.15; d&nbsp;=&nbsp;0.54 were non-significant. There were no compensatory changes in participant energy expenditure or energy intake for 48&nbsp;h post intervention. CONCLUSION: Reducing school day sitting time in adolescents\u27 resulted in significant improvements in apoB/apoA-1 ratio with medium effect sizes for total cholesterol, HDL cholesterol and total cholesterol/HDL ratio. Cognitive function results showed the equivalent of a 6&nbsp;month improvement in effective mental-attentional capacity. <br /

Additional file 2: of Acute effects of reducing sitting time in adolescents: a randomized cross-over study

Condition B: A ‘reduced sitting’ school day schedule. Description: A table demonstrating the protocol used to guide participants through the first condition: a ‘reduced sitting’ school day. (DOCX 12 kb

Healthy recovery: A stepped wedge cluster randomised controlled trial of a healthy lifestyle intervention for people attending residential alcohol and other drug treatment

Background: Unhealthy lifestyle behaviours contribute to the poor health of people attending alcohol and other drug (AOD) treatment. Healthy Recovery is an 8-session group-based intervention that targets smoking, diet and physical inactivity as part of an integrated healthy lifestyle approach. The current study aimed to examine the effectiveness of Healthy Recovery when delivered within residential AOD treatment settings. Methods: The study design was a stepped-wedge cluster randomised trial. Participants were 151 current smokers attending residential AOD programs provided by the Australian Salvation Army (n = 71, Control condition; n = 80, Intervention condition). The primary outcome was number of cigarettes smoked per day. Secondary outcomes examined other smoking behaviours (7-day point prevalence, use of nicotine replacement therapy [NRT]), diet (servings and variety of fruit and vegetables), and physical activity. Results: The mean number of cigarettes smoked per day was significantly lower in the Intervention condition at 2-, 5-, and 8-month follow-up. There were also significant differences in favour of the Intervention condition for number of quit attempts, use of NRT and variety of fruit. There were no other significant differences for other dietary or physical activity variables. Conclusions: Healthy Recovery had a positive impact on smoking behaviours. Future research should consider strategies to further promote smoking cessation (e.g. promoting longer-term use of NRT), as well as addressing physical activity and dietary behaviours. The introduction of broader organisational approaches (e.g. smoke free policies, organised group exercise and cooking activities) might help to enhance healthy lifestyle approaches within AOD treatment settings

Healthy recovery: A stepped wedge cluster randomised controlled trial of a healthy lifestyle intervention for people attending residential alcohol and other drug treatment

Background: Unhealthy lifestyle behaviours contribute to the poor health of people attending alcohol and other drug (AOD) treatment. Healthy Recovery is an 8-session group-based intervention that targets smoking, diet and physical inactivity as part of an integrated healthy lifestyle approach. The current study aimed to examine the effectiveness of Healthy Recovery when delivered within residential AOD treatment settings. Methods: The study design was a stepped-wedge cluster randomised trial. Participants were 151 current smokers attending residential AOD programs provided by the Australian Salvation Army (n = 71, Control condition; n = 80, Intervention condition). The primary outcome was number of cigarettes smoked per day. Secondary outcomes examined other smoking behaviours (7-day point prevalence, use of nicotine replacement therapy [NRT]), diet (servings and variety of fruit and vegetables), and physical activity. Results: The mean number of cigarettes smoked per day was significantly lower in the Intervention condition at 2-, 5-, and 8-month follow-up. There were also significant differences in favour of the Intervention condition for number of quit attempts, use of NRT and variety of fruit. There were no other significant differences for other dietary or physical activity variables. Conclusions: Healthy Recovery had a positive impact on smoking behaviours. Future research should consider strategies to further promote smoking cessation (e.g. promoting longer-term use of NRT), as well as addressing physical activity and dietary behaviours. The introduction of broader organisational approaches (e.g. smoke free policies, organised group exercise and cooking activities) might help to enhance healthy lifestyle approaches within AOD treatment settings