Product Quality Selection and Firm Survival. Evidence from the British Automobile Industry, 1895-1970.

This paper proposes an additional determininant of firm survival. Based on a detailed examination of firm survival in the British automobile industry between 1895 and 1970, we conclude that firm’s selection of submarket-defined by quality level-influenced survival. In contrast to findings for the US automobile industry, there is no evidence of first-mover advantage in the market as a whole. However, we do find evidence of first-mover advantage after conditioning on submarket choice.firm survival, product differentiation, submarket, product quality

Inter-tier Interference Suppression in Heterogeneous Cloud Radio Access Networks

Incorporating cloud computing into heterogeneous networks, the heterogeneous cloud radio access network (H-CRAN) has been proposed as a promising paradigm to enhance both spectral and energy efficiencies. Developing interference suppression strategies is critical for suppressing the inter-tier interference between remote radio heads (RRHs) and a macro base station (MBS) in H-CRANs. In this paper, inter-tier interference suppression techniques are considered in the contexts of collaborative processing and cooperative radio resource allocation (CRRA). In particular, interference collaboration (IC) and beamforming (BF) are proposed to suppress the inter-tier interference, and their corresponding performance is evaluated. Closed-form expressions for the overall outage probabilities, system capacities, and average bit error rates under these two schemes are derived. Furthermore, IC and BF based CRRA optimization models are presented to maximize the RRH-accessed users' sum rates via power allocation, which is solved with convex optimization. Simulation results demonstrate that the derived expressions for these performance metrics for IC and BF are accurate; and the relative performance between IC and BF schemes depends on system parameters, such as the number of antennas at the MBS, the number of RRHs, and the target signal-to-interference-plus-noise ratio threshold. Furthermore, it is seen that the sum rates of IC and BF schemes increase almost linearly with the transmit power threshold under the proposed CRRA optimization solution

Temperature compensation via cooperative stability in protein degradation

Temperature compensation is a notable property of circadian oscillators that indicates the insensitivity of the oscillator system's period to temperature changes; the underlying mechanism, however, is still unclear. We investigated the influence of protein dimerization and cooperative stability in protein degradation on the temperature compensation ability of two oscillators. Here, cooperative stability means that high-order oligomers are more stable than their monomeric counterparts. The period of an oscillator is affected by the parameters of the dynamic system, which in turn are influenced by temperature. We adopted the Repressilator and the Atkinson oscillator to analyze the temperature sensitivity of their periods. Phase sensitivity analysis was employed to evaluate the period variations of different models induced by perturbations to the parameters. Furthermore, we used experimental data provided by other studies to determine the reasonable range of parameter temperature sensitivity. We then applied the linear programming method to the oscillatory systems to analyze the effects of protein dimerization and cooperative stability on the temperature sensitivity of their periods, which reflects the ability of temperature compensation in circadian rhythms. Our study explains the temperature compensation mechanism for circadian clocks. Compared with the no-dimer mathematical model and linear model for protein degradation, our theoretical results show that the nonlinear protein degradation caused by cooperative stability is more beneficial for realizing temperature compensation of the circadian clock.Comment: 27 pages, 5 figure

Stomata at the crossroad of molecular interaction between biotic and abiotic stress responses in plants

Increasing global food production is threatened by harsh environmental conditions along with biotic stresses, requiring massive new research into integrated stress resistance in plants. Stomata play a pivotal role in response to many biotic and abiotic stresses, but their orchestrated interactions at the molecular, physiological, and biochemical levels were less investigated. Here, we reviewed the influence of drought, pathogen, and insect herbivory on stomata to provide a comprehensive overview in the context of stomatal regulation. We also summarized the molecular mechanisms of stomatal response triggered by these stresses. To further investigate the effect of stomata–herbivore interaction at a transcriptional level, integrated transcriptome studies from different plant species attacked by different pests revealed evidence of the crosstalk between abiotic and biotic stress. Comprehensive understanding of the involvement of stomata in some plant– herbivore interactions may be an essential step towards herbivores’ manipulation of plants, which provides insights for the development of integrated pest management strategies. Moreover, we proposed that stomata can function as important modulators of plant response to stress combination, representing an exciting frontier of plant science with a broad and precise view of plant biotic interactions