3 research outputs found
Analysis of X-knife and surgery in treatment of arteriovenous malformation of brain
Background: The goal of treatment in arteriovenous malformation (AVM)
is total obliteration of the AVM, restoration of normal cerebral
function, and preservation of life and neurological function. Aim: To
analyze the results of X-knife and surgery for AVM of the brain. The
endpoints for success or failure were as follows: success was defined
as angiographic obliteration and failure as residual lesion, requiring
retreatment, or death due to hemorrhage from the AVM. Materials and
Methods: From May 2002 to May 2007, 54 patients were enrolled for this
study. Grade I AVM was seen in 9%, grade II in 43%, grade III in 26%,
grade IV in 9%, and grade V in 13%. Thirty-eight patients were treated
by microsurgical resection out of which Grade I was seen in 5 patients,
Grade II was seen in 17 patients, Grade III was seen in 9 patients and
Grade V was seen in 7 patients. Rest of the sixteen patients were
treated by linear accelerator radiosurgery out of which Grade II was
seen in 6 patients, Grade III was seen in 5 patients and Grade IV was
seen in 5 patients. The follow up was in range of 3-63 months. In
follow up, digital subtraction angiography/ magnetic resonance
angiography (DSA/MRA) was performed 3 months after surgery and 1 year
and 2 years after stereotactic radiosurgery (SRS). Results: Among the
patients treated with X-knife, 12/16 (75%) had proven angiographic
obliteration. Complications were seen in 4/16 (25%) patients. Among the
patients treated with microsurgical resection, 23/38 (61%) had proven
angiographic obliteration. Complications (both intraoperative and
postoperative) were seen in 19/38 (50%) patients. Conclusions:
Sixty-one percent of patients were candidates for surgical resection.
X-knife is a good modality of treatment for a low-grade AVM situated in
eloquent areas of the brain and also for high-grade AVMs, when the
surgical risk and morbidity is high
Analysis of X-knife and surgery in treatment of arteriovenous malformation of brain
<b>Background:</b> The goal of treatment in arteriovenous malformation (AVM) is total obliteration of the AVM, restoration of normal cerebral function, and preservation of life and neurological function. <b>Aim:</b> To analyze the results of X-knife and surgery for AVM of the brain. The endpoints for success or failure were as follows: success was defined as angiographic obliteration and failure as residual lesion, requiring retreatment, or death due to hemorrhage from the AVM. <b>Materials and Methods:</b> From May 2002 to May 2007, 54 patients were enrolled for this study. Grade I AVM was seen in 9%, grade II in 43%, grade III in 26%, grade IV in 9%, and grade V in 13%. Thirty-eight patients were treated by microsurgical resection out of which Grade I was seen in 5 patients, Grade II was seen in 17 patients, Grade III was seen in 9 patients and Grade V was seen in 7 patients. Rest of the sixteen patients were treated by linear accelerator radiosurgery out of which Grade II was seen in 6 patients, Grade III was seen in 5 patients and Grade IV was seen in 5 patients. The follow up was in range of 3-63 months. In follow up, digital subtraction angiography/ magnetic resonance angiography (DSA/MRA) was performed 3 months after surgery and 1 year and 2 years after stereotactic radiosurgery (SRS). <b>Results: </b> Among the patients treated with X-knife, 12/16 (75%) had proven angiographic obliteration. Complications were seen in 4/16 (25%) patients. Among the patients treated with microsurgical resection, 23/38 (61%) had proven angiographic obliteration. Complications (both intraoperative and postoperative) were seen in 19/38 (50%) patients. <b>Conclusions:</b> Sixty-one percent of patients were candidates for surgical resection. X-knife is a good modality of treatment for a low-grade AVM situated in eloquent areas of the brain and also for high-grade AVMs, when the surgical risk and morbidity is high
Analysis of X-knife and surgery in treatment of arteriovenous malformation of brain
Background: The goal of treatment in arteriovenous malformation (AVM)
is total obliteration of the AVM, restoration of normal cerebral
function, and preservation of life and neurological function. Aim: To
analyze the results of X-knife and surgery for AVM of the brain. The
endpoints for success or failure were as follows: success was defined
as angiographic obliteration and failure as residual lesion, requiring
retreatment, or death due to hemorrhage from the AVM. Materials and
Methods: From May 2002 to May 2007, 54 patients were enrolled for this
study. Grade I AVM was seen in 9%, grade II in 43%, grade III in 26%,
grade IV in 9%, and grade V in 13%. Thirty-eight patients were treated
by microsurgical resection out of which Grade I was seen in 5 patients,
Grade II was seen in 17 patients, Grade III was seen in 9 patients and
Grade V was seen in 7 patients. Rest of the sixteen patients were
treated by linear accelerator radiosurgery out of which Grade II was
seen in 6 patients, Grade III was seen in 5 patients and Grade IV was
seen in 5 patients. The follow up was in range of 3-63 months. In
follow up, digital subtraction angiography/ magnetic resonance
angiography (DSA/MRA) was performed 3 months after surgery and 1 year
and 2 years after stereotactic radiosurgery (SRS). Results: Among the
patients treated with X-knife, 12/16 (75%) had proven angiographic
obliteration. Complications were seen in 4/16 (25%) patients. Among the
patients treated with microsurgical resection, 23/38 (61%) had proven
angiographic obliteration. Complications (both intraoperative and
postoperative) were seen in 19/38 (50%) patients. Conclusions:
Sixty-one percent of patients were candidates for surgical resection.
X-knife is a good modality of treatment for a low-grade AVM situated in
eloquent areas of the brain and also for high-grade AVMs, when the
surgical risk and morbidity is high