Characteristics of Studies Included in the Meta-analysis.

<p>Abbreviations: PEM, pemetrexed; GEM, gemcitabine; Doc, docetaxel; P, cisplatin; P#, carboplatin; Ade, adenocarcinoma; Non-squ, non-squamous cell carcinoma; AUC, area under the concentration/time curve. NA, not available; OS, overall survival; progression-free survival.</p

Comparison of response rate between pemetrexed plus platinum chemotherapy and other platinum-based regimens.

<p>Abbreviations: M-H, mantel-haenszel; CI, confidence interval.</p

Summary of grade 3–4 hematological toxicity.

<p>Abbreviations: M-H, mantel-haenszel; CI, confidence interval.</p

Comparison of progression-free survival between pemetrexed plus platinum chemotherapy and other platinum-based regimens.

<p>Abbreviations: SE, standard error; IV, inverse variance; CI, confidence interval.</p

Summary of grade 3–4 nonhematological toxicity.

<p>Abbreviations: M-H, mantel-haenszel; CI, confidence interval.</p

Comparison of overall survival in patients with nonsquamous histology between pemetrexed plus platinum chemotherapy and other platinum-based regimens.

<p>Abbreviations: SE, standard error; IV, inverse variance; CI, confidence interval.</p