Acute parkinsonism in Cryptococcus gattii meningoencephalitis: Extensive lesions in basal ganglia

Universidade Federal de São Paulo, Dept Neurol, BR-04023900 São Paulo, BrazilUniversidade Federal de São Paulo, Dept Neurol, BR-04023900 São Paulo, BrazilWeb of Scienc

Akathisia: An unusual movement disorder in Machado-Joseph disease

Universidade Federal de São Paulo, Div Gen Neurol & Ataxias, Dept Neurol & Neurosurg, São Paulo, BrazilUniv Fed Rio Grande do Sul, Dept Internal Med, Brazil Hosp, Clin Porto Alegre, BR-90046900 Porto Alegre, RS, BrazilUniv Fed Rio Grande do Sul, Dept Biochem, Brazil Hosp, Clin Porto Alegre, BR-90046900 Porto Alegre, RS, BrazilUniversidade Federal de São Paulo, Div Gen Neurol & Ataxias, Dept Neurol & Neurosurg, São Paulo, BrazilWeb of Scienc

Restless legs syndrome associated with Guillain-Barre syndrome: A report of two cases

Universidade Federal de São Paulo, Dept Neurol & Neurosurg, BR-04023900 São Paulo, BrazilHosp & Maternidade Sao Camilo Pompeia, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Neurol & Neurosurg, BR-04023900 São Paulo, BrazilWeb of Scienc

Teaching NeuroImages: A prematurely aging patient presenting with severe leukoaraiosis and stroke

Universidade Federal de São Paulo, Dept Neurol & Neurosurg, São Paulo, BrazilHosp Sick Children, Toronto, ON M5G 1X8, CanadaUniversidade Federal de São Paulo, Dept Neurol & Neurosurg, São Paulo, BrazilWeb of Scienc

Nonmotor and extracerebellar features in Machado-Joseph disease: A review

Spinocerebellar ataxia type 3 or Machado-Joseph disease is the most common spinocerebellar ataxia worldwide, and the high frequency of nonmotor manifestations in Machado-Joseph disease demonstrates how variable is the clinical expression of this single genetic entity. Anatomical, physiological, clinical, and functional neuroimaging data reinforce the idea of a degenerative process involving extracerebellar regions of the nervous system in Machado-Joseph disease. Brain imaging and neuropathologic studies have revealed atrophy of the pons, basal ganglia, midbrain, medulla oblongata, multiple cranial nerve nuclei, and thalamus and of the frontal, parietal, temporal, occipital, and limbic lobes. This review provides relevant information about nonmotor manifestations and extracerebellar symptoms in Machado-Joseph disease. the main nonmotor manifestations of Machado-Joseph disease described in previous data and discussed in this article are: sleep disorders, cognitive and affective disturbances, psychiatric symptoms, olfactory dysfunction, peripheral neuropathy, pain, cramps, fatigue, nutritional problems, and dysautonomia. in addition, we conducted a brief discussion of noncerebellar motor manifestations, highlighting movement disorders. (c) 2013 Movement Disorder SocietyUniversidade Federal de São Paulo, Dept Neurol, Gen Neurol & Ataxia Unit, São Paulo, BrazilUniv Campinas Unicamp, Dept Neurol, São Paulo, BrazilUniv Fed Rio Grande do Sul, Dept Biochem, Porto Alegre, RS, BrazilHosp Clin Porto Alegre, Med Genet Serv, Porto Alegre, RS, BrazilUniv Fed Rio Grande do Sul, Postgrad Program Med Sci, Porto Alegre, RS, BrazilUniv Fed Parana UFPR, Hosp Clin, Dept Internal Med, Movement Disorders Unit, Curitiba, Parana, BrazilUniv Fed Minas Gerais, Dept Internal Med, Fac Med, Cognit & Behav Neurol Unit, Belo Horizonte, MG, BrazilUniv Fed Rio Grande do Sul, Dept Internal Med, Porto Alegre, RS, BrazilUniv Campinas UNICAMP, Sch Med Sci, Dept Med Genet, Campinas, SP, BrazilUniversidade Federal de São Paulo, Dept Neurol, Gen Neurol & Ataxia Unit, São Paulo, BrazilWeb of Scienc