35,385 research outputs found
Heat-sterilizable power source study for advanced Mariner missions
Heat sterilizable power sources for Mariner Mars landing capsul
On the nonlinear statistics of range image patches
In [A. B. Lee, K. S. Pedersen, and D. Mumford, Int. J. Comput. Vis., 54 (2003), pp. 83â103], the authors study the distributions of 3 Ă 3 patches from optical images and from range images. In [G. Carlsson, T. Ishkanov, V. de Silva, and A. Zomorodian, Int. J. Comput. Vis., 76 (2008), pp.
1â12], the authors apply computational topological tools to the data set of optical patches studied by Lee, Pedersen, and Mumford and find geometric structures for high density subsets. One high density subset is called the primary circle and essentially consists of patches with a line separating a light and a dark region. In this paper, we apply the techniques of Carlsson et al. to range patches.
By enlarging to 5Ă5 and 7Ă7 patches, we find core subsets that have the topology of the primary circle, suggesting a stronger connection between optical patches and range patches than was found by Lee, Pedersen, and Mumford
Ballerina - Pirouettes in Search of Gamma Bursts
The cosmological origin of gamma ray bursts has now been established with
reasonable certainty. Many more bursts will need to be studied to establish the
typical distance scale, and to map out the large diversity in properties which
have been indicated by the first handful of events. We are proposing Ballerina,
a small satellite to provide accurate positions and new data on the gamma-ray
bursts. We anticipate a detection rate an order of magnitude larger than
obtained from Beppo-SAX.Comment: A&AS in press, proceedings of the Workshop "Gamma Ray Bursts in the
Afterglow Era" in Rome, November 199
Knowledge Flows through Informal Contacts in Industrial Clusters Myths or Realities?
The role of informal networks in the development of regional clusters has received a lot of attention in the literature recently. Informal contact between employees in different firms is argued to be one of the main carriers of knowledge between firms in a cluster. This paper empirically examines the role of informal contacts in a specific cluster. In a recent questionnaire, we ask a sample of engineers in a regional cluster of wireless communication firms in Northern Denmark, a series of questions on informal networks. We analyze whether the engineers actually acquire valuable knowledge through these networks. We find that the engineers do share even valuable knowledge with informal contacts. This shows that informal contacts are important channels of knowledge diffusion.Informal contacts, regional clusters, communication technology
Dirac model of electronic transport in graphene antidot barriers
In order to use graphene for semiconductor applications, such as transistors
with high on/off ratios, a band gap must be introduced into this otherwise
semimetallic material. A promising method of achieving a band gap is by
introducing nanoscale perforations (antidots) in a periodic pattern, known as a
graphene antidot lattice (GAL). A graphene antidot barrier (GAB) can be made by
introducing a 1D GAL strip in an otherwise pristine sheet of graphene. In this
paper, we will use the Dirac equation (DE) with a spatially varying mass term
to calculate the electronic transport through such structures. Our approach is
much more general than previous attempts to use the Dirac equation to calculate
scattering of Dirac electrons on antidots. The advantage of using the DE is
that the computational time is scale invariant and our method may therefore be
used to calculate properties of arbitrarily large structures. We show that the
results of our Dirac model are in quantitative agreement with tight-binding for
hexagonal antidots with armchair edges. Furthermore, for a wide range of
structures, we verify that a relatively narrow GAB, with only a few antidots in
the unit cell, is sufficient to give rise to a transport gap
Dapagliflozin stimulates glucagon secretion at high glucose: experiments and mathematical simulations of human A-cells.
Glucagon is one of the main regulators of blood glucose levels and dysfunctional stimulus secretion coupling in pancreatic A-cells is believed to be an important factor during development of diabetes. However, regulation of glucagon secretion is poorly understood. Recently it has been shown that Na(+)/glucose co-transporter (SGLT) inhibitors used for the treatment of diabetes increase glucagon levels in man. Here, we show experimentally that the SGLT2 inhibitor dapagliflozin increases glucagon secretion at high glucose levels both in human and mouse islets, but has little effect at low glucose concentrations. Because glucagon secretion is regulated by electrical activity we developed a mathematical model of A-cell electrical activity based on published data from human A-cells. With operating SGLT2, simulated glucose application leads to cell depolarization and inactivation of the voltage-gated ion channels carrying the action potential, and hence to reduce action potential height. According to our model, inhibition of SGLT2 reduces glucose-induced depolarization via electrical mechanisms. We suggest that blocking SGLTs partly relieves glucose suppression of glucagon secretion by allowing full-scale action potentials to develop. Based on our simulations we propose that SGLT2 is a glucose sensor and actively contributes to regulation of glucagon levels in humans which has clinical implications
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