61 research outputs found
Off-lining to tape is not archiving: Why we need real archiving to support media archaeology and ensure our visual effects legacy thrives
- Publication venue
- 'Association for Computing Machinery (ACM)'
- Publication date
- 01/08/2019
- Field of study
© 2019 ISAST This paper examines digital asset archiving and preservation practice in the visual effects (VFX) industry. The authors briefly summarize media archaeology theory and provide an overview of how VFX studios presently archive project assets and records, based on case study and interview research conducted with expert VFX practitioners from leading international studios. In addition, the authors propose that current practice could be improved by adopting archival science methods, including digital preservation practices. Doing so will support media archaeology studies of digital cultures over time and ensure that the legacy of VFX creative and technical production thrives for future generations
Lawson Criterion for Ignition Exceeded in an Inertial Fusion Experiment
- Author
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- Zaitseva N
- Zaka F
- Ze F
- Zeiger B
- Zika M
- Zimmerman G
- Zobrist T
- Zuegel J
- Zylstra A
- Publication venue
- Publication date
- 01/01/2022
- Field of study
Lawson criterion for ignition exceeded in an inertial fusion experiment
- Author
- Abu-Shawareb H
- Acree R
- Adams J
- Adams P
- Addis B
- Aden R
- Adrian P
- Afeyan BB
- Aggleton M
- Aghaian L
- Aguirre A
- Aikens D
- Akre J
- Albert F
- Albrecht M
- Albright BJ
- Albritton J
- Alcala J
- Alday C
- Alessi DA
- Alexander N
- Alfonso J
- Alfonso N
- Alger E
- Ali SJ
- Ali ZA
- Alley WE
- Amala P
- Amendt PA
- Amick P
- Ammula S
- Amorin C
- Ampleford DJ
- Anderson RW
- Anklam T
- Antipa N
- Appelbe B
- Aracne-Ruddle C
- Araya E
- Arend M
- Arnold P
- Arnold T
- Asay J
- Atherton LJ
- Atkinson D
- Atkinson R
- Auerbach JM
- Austin B
- Auyang L
- Awwal AS
- Ayers J
- Ayers S
- Ayers T
- Azevedo S
- Bachmann B
- Back CA
- Bae J
- Bailey DS
- Bailey J
- Baisden T
- Baker KL
- Baldis H
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- Barker D
- Barnes A
- Barnes CW
- Barrios MA
- Barty C
- Bass I
- Batha SH
- Baxamusa SH
- Bazan G
- Beagle JK
- Beale R
- Beck BR
- Beck JB
- Bedzyk M
- Beeler RG
- Beeler RG
- Behrendt W
- Belk L
- Bell P
- Belyaev M
- Benage JF
- Benedetti LR
- Benedict LX
- Bennett G
- Berger R
- Bernat T
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- Bertolini L
- Berzak Hopkins L
- Besenbruch G
- Betcher J
- Bettenhausen R
- Betti R
- Bezzerides B
- Bhandarkar SD
- Bickel R
- Biener J
- Biesiada T
- Bigelow K
- Bigelow-Granillo J
- Bigman V
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- Yatabe J
- Yeamans CB
- Yee BC
- Yi SA
- Yin L
- Young B
- Young CS
- Young CV
- Young P
- Youngblood K
- Zacharias R
- Zagaris G
- Zaitseva N
- Zaka F
- Ze F
- Zeiger B
- Zika M
- Zimmerman GB
- Zobrist T
- Zuegel JD
- Zylstra AB
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 06/07/2022
- Field of study
For more than half a century, researchers around the world have been engaged in attempts to achieve fusion ignition as a proof of principle of various fusion concepts. Following the Lawson criterion, an ignited plasma is one where the fusion heating power is high enough to overcome all the physical processes that cool the fusion plasma, creating a positive thermodynamic feedback loop with rapidly increasing temperature. In inertially confined fusion, ignition is a state where the fusion plasma can begin "burn propagation" into surrounding cold fuel, enabling the possibility of high energy gain. While "scientific breakeven" (i.e., unity target gain) has not yet been achieved (here target gain is 0.72, 1.37Â MJ of fusion for 1.92Â MJ of laser energy), this Letter reports the first controlled fusion experiment, using laser indirect drive, on the National Ignition Facility to produce capsule gain (here 5.8) and reach ignition by nine different formulations of the Lawson criterion
Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
- Author
- Abajobir Amanuel Alemu
- Abate Kalkidan Hassen
- Abbafati Cristiana
- Abbas Kaja M.
- Abd-Allah Foad
- Abdulle Abdishakur M.
- Abebo Teshome Abuka
- Abera Semaw Ferede
- Aboyans Victor
- Abu-Raddad Laith J.
- Ackerman Ilana N.
- Adamu Abdu Abdullahi
- Adetokunboh Olatunji
- Afarideh Mohsen
- Afshin Ashkan
- Agarwal Sanjay Kumar
- Aggarwal Rakesh
- Agrawal Anurag
- Agrawal Sutapa
- Ahmad Kiadaliri Aliasghar
- Ahmadieh Hamid
- Ahmed Muktar Beshir
- Aichour Amani Nidhal
- Aichour Ibtihel
- Aichour Miloud Taki Eddine
- Aiyar Sneha
- Akinyemi Rufus Olusola
- Akseer Nadia
- Al Lami Faris Hasan
- Al-Aly Ziyad
- Al-Maskari Fatma
- Al-Raddadi Rajaa
- Alahdab Fares
- Alam Khurshid
- Alam Noore
- Alam Tahiya
- Alasfoor Deena
- Alene Kefyalew Addis
- Ali Raghib
- Alizadeh-Navaei Reza
- Alkerwi Ala'a
- Alla François
- Allebeck Peter
- Allen Christine
- Alsharif Ubai
- Alsowaidi Shirina
- Altirkawi Khalid A.
- Amare Azmeraw T.
- Amini Erfan
- Ammar Walid
- Amoako Yaw Ampem
- Andersen Hjalte H.
- Antonio Carl Abelardo T.
- Anwari Palwasha
- Artaman Al
- Aryal Krishna Kumar
- Asayesh Hamid
- Asgedom Solomon W.
- Assadi Reza
- Atey Tesfay Mehari
- Atnafu Niguse Tadele
- Atre Sachin R.
- Avila-Burgos Leticia
- Avokpaho Euripide Frinel G. Arthur
- Awasthi Ashish
- Ayala Quintanilla Beatriz Paulina
- Ba Saleem Huda Omer
- Bacha Umar
- Badawi Alaa
- Balakrishnan Kalpana
- Banerjee Amitava
- Bannick Marlena S.
- Barac Aleksandra
- Barber Ryan M.
- Barker-Collo Suzanne L.
- Barquera Simon
- Barregard Lars
- Barrero Lope H.
- Basu Sanjay
- Battista Bob
- Battle Katherine E.
- Baune Bernhard T.
- Bazargan-Hejazi Shahrzad
- Beardsley Justin
- Bedi Neeraj
- Beghi Ettore
- Bekele Bayu Begashaw
- Bell Michelle L.
- Bennett Derrick A.
- Bensenor Isabela M.
- Benson Jennifer
- Berhane Adugnaw
- Berhe Derbew Fikadu
- Bernabé Eduardo
- Betsu Balem Demtsu
- Beuran Mircea
- Beyene Addisu Shunu
- Bhala Neeraj
- Bhansali Anil
- Bhatt Samir
- Bhutta Zulfiqar A.
- Biadgilign Sibhatu
- Bienhoff Kelly
- Bikbov Boris
- Birungi Charles
- Biryukov Stan
- Bisanzio Donal
- Bizuayehu Habtamu Mellie
- Boneya Dube Jara
- Boufous Soufiane
- Bourne Rupert R.A.
- Brazinova Alexandra
- Brugha Traolach S.
- Buchbinder Rachelle
- Bulto Lemma Negesa Bulto
- Bumgarner Blair R.
- Butt Zahid A.
- Bärnighausen Till
- Béjot Yannick
- Cahuana-Hurtado Lucero
- Cameron Ewan
- Car Mate
- Carabin Hélène
- Carapetis Jonathan R.
- Carpenter David O.
- Carrero Juan Jesus
- Carter Austin
- Carvalho Felix
- Casey Daniel C.
- Caso Valeria
- Castañeda-Orjuela Carlos A.
- Castle Chris D.
- Catalá-López Ferrán
- Chang Hsing-Yi
- Chang Jung-Chen
- Charlson Fiona J.
- Chen Honglei
- Chibalabala Mirriam
- Chibueze Chioma Ezinne
- Chisumpa Vesper Hichilombwe
- Chitheer Abdulaal A.
- Christopher Devasahayam Jesudas
- Ciobanu Liliana G.
- Cirillo Massimo
- Colombara Danny
- Cooper Cyrus
- Cortesi Paolo Angelo
- Criqui Michael H.
- Crump John A.
- Cárdenas Rosario
- Dadi Abel Fekadu
- Dalal Koustuv
- Dandona Lalit
- Dandona Rakhi
- Das Neves José
- Davitoiu Dragos V.
- De Courten Barbora
- De Leo Diego
- Degenhardt Louisa
- Deiparine Selina
- Dellavalle Robert P.
- Deribe Kebede
- Des Jarlais Don C.
- Dey Subhojit
- Dharmaratne Samath D.
- Dhillon Preet Kaur
- Dicker Daniel
- Ding Eric L.
- Djalalinia Shirin
- Do Huyen Phuc
- Dorsey E. Ray
- Dos Santos Kadine Priscila Bender
- Douwes-Schultz Dirk
- Doyle Kerrie E.
- Driscoll Tim R.
- Dubey Manisha
- Duncan Bruce Bartholow
- El-Khatib Ziad Ziad
- Ellerstrand Jerisha
- Enayati Ahmadali
- Endries Aman Yesuf
- Ermakov Sergey Petrovich
- Erskine Holly E.
- Eshrati Babak
- Eskandarieh Sharareh
- Esteghamati Alireza
- Estep Kara
- Fanuel Fanuel Belayneh Bekele
- Farinha Carla Sofia E. Sa
- Faro André
- Farzadfar Farshad
- Fazeli Mir Sohail
- Feigin Valery L.
- Fereshtehnejad Seyed-Mohammad
- Fernandes João C.
- Ferrari Alize J.
- Feyissa Tesfaye Regassa
- Filip Irina
- Fischer Florian
- Fitzmaurice Christina
- Flaxman Abraham D.
- Flor Luisa Sorio
- Foigt Nataliya
- Foreman Kyle J.
- Franklin Richard C.
- Fullman Nancy
- Furtado Joao M.
- Futran Neal D.
- Fürst Thomas
- Gakidou Emmanuela
- Ganji Morsaleh
- Garcia-Basteiro Alberto L.
- Gebre Teshome
- Gebrehiwot Tsegaye Tewelde
- Geleto Ayele
- Gemechu Bikila Lencha
- Gesesew Hailay Abrha
- Gething Peter W.
- Ghajar Alireza
- Gibney Katherine B.
- Gill Paramjit Singh
- Gillum Richard F.
- Ginawi Ibrahim Abdelmageem Mohamed
- Giref Ababi Zergay
- Gishu Melkamu Dedefo
- Giussani Giorgia
- Godwin William W.
- Gold Audra L.
- Goldberg Ellen M.
- Gona Philimon N.
- Goodridge Amador
- Gopalani Sameer Vali
- Goto Atsushi
- Goulart Alessandra Carvalho
- Griswold Max
- Gugnani Harish Chander
- Gupta Rahul
- Gupta Rajeev
- Gupta Tanush
- Gupta Vipin
- Hafezi-Nejad Nima
- Hailu Alemayehu Desalegne
- Hailu Gessessew Bugssa
- Hamadeh Randah Ribhi
- Hamidi Samer
- Handal Alexis J.
- Hankey Graeme J.
- Hao Yuantao
- Harb Hilda L.
- Hareri Habtamu Abera
- Haro Josep Maria
- Harvey James
- Hassanvand Mohammad Sadegh
- Havmoeller Rasmus
- Hawley Caitlin
- Hay Roderick J.
- Hay Simon I.
- Henry Nathaniel J.
- Heredia-Pi Ileana Beatriz
- Hernandez Julio Montañez
- Heydarpour Pouria
- Hoek Hans W.
- Hoffman Howard J.
- Horita Nobuyuki
- Hosgood H. Dean
- Hostiuc Sorin
- Hotez Peter J.
- Hoy Damian G.
- Htet Aung Soe
- Hu Guoqing
- Huang Hsiang
- Huynh Chantal
- Iburg Kim Moesgaard
- Igumbor Ehimario Uche
- Ikeda Chad
- Irvine Caleb Mackay Salpeter
- Jacobsen Kathryn H.
- Jahanmehr Nader
- Jakovljevic Mihajlo B.
- Jassal Simerjot K.
- Javanbakht Mehdi
- Jayaraman Sudha P.
- Jeemon Panniyammakal
- Jensen Paul N.
- Jha Vivekanand
- Jiang Guohong
- John Denny
- Johnson Catherine O.
- Johnson Sarah Charlotte
- Jonas Jost B.
- Jürisson Mikk
- Kabir Zubair
- Kadel Rajendra
- Kahsay Amaha
- Kamal Ritul
- Kan Haidong
- Karam Nadim E.
- Karch André
- Karema Corine Kakizi
- Kasaeian Amir
- Kassa Getachew Mullu
- Kassaw Nigussie Assefa
- Kassebaum Nicholas J.
- Kastor Anshul
- Katikireddi Srinivasa Vittal
- Kaul Anil
- Kawakami Norito
- Keiyoro Peter Njenga
- Kengne Andre Pascal
- Keren Andre
- Khader Yousef Saleh
- Khalil Ibrahim A.
- Khan Ejaz Ahmad
- Khang Young-Ho
- Khosravi Ardeshir
- Khubchandani Jagdish
- Kieling Christian
- Kim Daniel
- Kim Pauline
- Kim Yun Jin
- Kimokoti Ruth W.
- Kinfu Yohannes
- Kisa Adnan
- Kissimova-Skarbek Katarzyna A.
- Kivimaki Mika
- Knudsen Ann Kristin
- Kokubo Yoshihiro
- Kolte Dhaval
- Kopec Jacek A.
- Kosen Soewarta
- Koul Parvaiz A.
- Koyanagi Ai
- Kravchenko Michael
- Krishnaswami Sanjay
- Krohn Kristopher J.
- Kuate Defo Barthelemy
- Kucuk Bicer Burcu
- Kumar G. Anil
- Kumar Pushpendra
- Kumar Sanjiv
- Kyu Hmwe H.
- Lal Dharmesh Kumar
- Lalloo Ratilal
- Lambert Nkurunziza
- Lan Qing
- Larsson Anders
- Lavados Pablo M.
- Leasher Janet L.
- Lee Jong-Tae
- Lee Paul H.
- Leigh James
- Leshargie Cheru Tesema
- Leung Janni
- Leung Ricky
- Levi Miriam
- Li Kappe Darya
- Li Yichong
- Li Yongmei
- Liang Xiaofeng
- Liben Misgan Legesse
- Lim Stephen S.
- Linn Shai
- Liu Angela
- Liu Patrick Y.
- Liu Shiwei
- Liu Yang
- Lodha Rakesh
- Logroscino Giancarlo
- London Stephanie J.
- Looker Katharine J.
- Lopez Alan D.
- Lorkowski Stefan
- Lotufo Paulo A.
- Low Nicola
- Lozano Rafael
- Lucas Timothy C.D.
- Macarayan Erlyn Rachelle King
- Magdy Abd El Razek Hassan
- Magdy Abd El Razek Mohammed
- Mahdavi Mahdi
- Majdan Marek
- Majdzadeh Reza
- Majeed Azeem
- Malekzadeh Reza
- Malhotra Rajesh
- Malta Deborah Carvalho
- Mamun Abdullah A.
- Manguerra Helena
- Manhertz Treh
- Mantilla Ana
- Mantovani Lorenzo G.
- Mapoma Chabila C.
- Marczak Laurie B.
- Martinez-Raga Jose
- Martins-Melo Francisco Rogerlândio
- Martopullo Ira
- Mathur Manu Raj
- Mazidi Mohsen
- McAlinden Colm
- McGaughey Madeline
- McGrath John J.
- McKee Martin
- McNellan Claire
- Mehata Suresh
- Mehndiratta Man Mohan
- Mekonnen Tefera Chane
- Memiah Peter
- Memish Ziad A.
- Mendoza Walter
- Mengistie Mubarek Abera
- Mengistu Desalegn Tadese
- Mensah George A.
- Meretoja Atte
- Meretoja Tuomo J.
- Mezgebe Haftay Berhane
- Micha Renata
- Millear Anoushka
- Miller Ted R.
- Mills Edward J.
- Mirarefin Mojde
- Mirrakhimov Erkin M.
- Misganaw Awoke
- Mishra Shiva Raj
- Mitchell Philip B.
- Mohammad Karzan Abdulmuhsin
- Mohammadi Alireza
- Mohammed Kedir Endris
- Mohammed Shafiu
- Mohanty Sanjay K.
- Mokdad Ali H.
- Mollenkopf Sarah K.
- Monasta Lorenzo
- Montico Marcella
- Moradi-Lakeh Maziar
- Moraga Paula
- Mori Rintaro
- Morozoff Chloe
- Morrison Shane D.
- Moses Mark
- Mountjoy-Venning Cliff
- Mruts Kalayu Birhane
- Mueller Ulrich O.
- Muller Kate
- Murdoch Michele E.
- Murray Christopher J.L.
- Murthy Gudlavalleti Venkata Satyanarayana
- Musa Kamarul Imran
- März Winfried
- Nachega Jean B.
- Nagel Gabriele
- Naghavi Mohsen
- Naheed Aliya
- Naidoo Kovin S.
- Naldi Luigi
- Nangia Vinay
- Natarajan Gopalakrishnan
- Negasa Dumessa Edessa
- Negoi Ionut
- Negoi Ruxandra Irina
- Newton Charles R.
- Ngunjiri Josephine Wanjiku
- Nguyen Cuong Tat
- Nguyen Grant
- Nguyen Minh
- Nguyen Quyen Le
- Nguyen Trang Huyen
- Nichols Emma
- Ningrum Dina Nur Anggraini
- Nolte Sandra
- Nong Vuong Minh
- Norrving Bo
- Noubiap Jean Jacques N.
- O'Donnell Martin J.
- Ogbo Felix Akpojene
- Oh In-Hwan
- Okoro Anselm
- Oladimeji Olanrewaju
- Olagunju Andrew Toyin
- Olagunju Tinuke Oluwasefunmi
- Olsen Helen E.
- Olusanya Bolajoko Olubukunola
- Olusanya Jacob Olusegun
- Ong Kanyin
- Opio John Nelson
- Oren Eyal
- Ortiz Alberto
- Osgood-Zimmerman Aaron
- Osman Majdi
- Owolabi Mayowa O.
- Pa Mahesh
- Pacella Rosana E.
- Pana Adrian
- Panda Basant Kumar
- Papachristou Christina
- Park Eun-Kee
- Parry Charles D.
- Parsaeian Mahboubeh
- Patten Scott B.
- Patton George C.
- Paulson Katherine
- Pearce Neil
- Pereira David M.
- Perico Norberto
- Pesudovs Konrad
- Peterson Carrie Beth
- Petzold Max
- Phillips Michael Robert
- Pigott David M.
- Pillay Julian David
- Pinho Christine
- Plass Dietrich
- Pletcher Martin A.
- Popova Svetlana
- Poulton Richie G.
- Pourmalek Farshad
- Prabhakaran Dorairaj
- Prasad Narayan
- Prasad Noela M.
- Purcell Carrie
- Qorbani Mostafa
- Quansah Reginald
- Rabiee Rynaz H.S.
- Radfar Amir
- Rafay Anwar
- Rahimi Kazem
- Rahimi-Movaghar Afarin
- Rahimi-Movaghar Vafa
- Rahman Mahfuzar
- Rahman Mohammad Hifz Ur
- Rai Rajesh Kumar
- Rajsic Sasa
- Ram Usha
- Ranabhat Chhabi Lal
- Rankin Zane
- Rao Paturi Vishnupriya
- Rao Puja C.
- Rawaf Salman
- Ray Sarah E.
- Reiner Robert C.
- Reinig Nikolas
- Reitsma Marissa B.
- Remuzzi Giuseppe
- Renzaho Andre M.N.
- Resnikoff Serge
- Rezaei Satar
- Ribeiro Antonio L.
- Ronfani Luca
- Roshandel Gholamreza
- Roth Gregory A.
- Roy Ambuj
- Rubagotti Enrico
- Ruhago George Mugambage
- Saadat Soheil
- Sadat Nafis
- Safdarian Mahdi
- Safi Sare
- Safiri Saeid
- Sagar Rajesh
- Sahathevan Ramesh
- Salama Joseph
- Salomon Joshua A.
- Salvi Sundeep Santosh
- Samy Abdallah M.
- Sanabria Juan R.
- Santomauro Damian
- Santos Itamar S.
- Santos João Vasco
- Santric Milicevic Milena M.
- Sartorius Benn
- Satpathy Maheswar
- Sawhney Monika
- Saxena Sonia
- Schmidt Maria Inês
- Schneider Ione J.C.
- Schwebel David C.
- Schwendicke Falk
- Schöttker Ben
- Seedat Soraya
- Sepanlou Sadaf G.
- Servan-Mori Edson E.
- Setegn Tesfaye
- Shackelford Katya Anne
- Shaheen Amira
- Shaikh Masood Ali
- Shamsipour Mansour
- Shariful Islam Sheikh Mohammed
- Sharma Jayendra
- Sharma Rajesh
- She Jun
- Shi Peilin
- Shields Chloe
- Shigematsu Mika
- Shinohara Yukito
- Shiri Rahman
- Shirkoohi Reza
- Shirude Shreya
- Shishani Kawkab
- Shrime Mark G.
- Sibai Abla Mehio
- Sigfusdottir Inga Dora
- Silva Diego Augusto Santos
- Silva João Pedro
- Silveira Dayane Gabriele Alves
- Singh Jasvinder A.
- Singh Narinder Pal
- Sinha Dhirendra Narain
- Skiadaresi Eirini
- Skirbekk Vegard
- Slepak Erica Leigh
- Sligar Amber
- Smith David L.
- Smith Mari
- Sobaih Badr H.A.
- Sobngwi Eugene
- Sorensen Reed J.D.
- Sousa Tatiane Cristina Moraes
- Sposato Luciano A.
- Sreeramareddy Chandrashekhar T.
- Srinivasan Vinay
- Stanaway Jeffrey D.
- Stathopoulou Vasiliki
- Steel Nicholas
- Stein Dan J.
- Stein Murray B.
- Steiner Caitlyn
- Steiner Timothy J.
- Steinke Sabine
- Stokes Mark Andrew
- Stovner Lars Jacob
- Strub Bryan
- Subart Michelle
- Sufiyan Muawiyyah Babale
- Suliankatchi Abdulkader Rizwan
- Sunguya Bruno F.
- Sur Patrick J.
- Swaminathan Soumya
- Sykes Bryan L.
- Sylte Dillon O.
- Tabarés-Seisdedos Rafael
- Taffere Getachew Redae
- Takala Jukka S.
- Tandon Nikhil
- Tavakkoli Mohammad
- Taveira Nuno
- Taylor Hugh R.
- Tehrani-Banihashemi Arash
- Tekelab Tesfalidet
- Temam Shifa Girma
- Terkawi Abdullah Sulieman
- Tesfaye Dawit Jember
- Tesssema Belay
- Thamsuwan Ornwipa
- Thomas Katie E.
- Thrift Amanda G.
- Tiruye Tenaw Yimer
- Tobe-Gai Ruoyan
- Tollanes Mette C.
- Tonelli Marcello
- Topor-Madry Roman
- Tortajada Miguel
- Touvier Mathilde
- Tran Bach Xuan
- Tripathi Suryakant
- Troeger Christopher
- Truelsen Thomas
- Tsoi Derrick
- Tuem Kald Beshir
- Tuzcu Emin Murat
- Tyrovolas Stefanos
- Ukwaja Kingsley N.
- Undurraga Eduardo A.
- Uneke Chigozie Jesse
- Updike Rachel
- Uthman Olalekan A.
- Uzochukwu Benjamin S. Chudi
- Van Boven Job F.M.
- Varughese Santosh
- Vasankari Tommi
- Venkatesh
- Venketasubramanian Narayanaswamy
- Vidavalur Ramesh
- Violante Francesco S.
- Vladimirov Sergey K.
- Vlassov Vasiliy Victorovich
- Vollset Stein Emil
- Vos Theo
- Wadilo Fiseha
- Wakayo Tolassa
- Wang Yuan-Pang
- Weaver Marcia
- Weichenthal Scott
- Weiderpass Elisabete
- Weintraub Robert G.
- Werdecker Andrea
- Westerman Ronny
- Whiteford Harvey A.
- Wijeratne Tissa
- Wiysonge Charles Shey
- Wolfe Charles D.A.
- Woodbrook Rachel
- Woolf Anthony D.
- Workicho Abdulhalik
- Wulf Hanson Sarah
- Xavier Denis
- Xu Gelin
- Yadgir Simon
- Yaghoubi Mohsen
- Yakob Bereket
- Yan Lijing L.
- Yano Yuichiro
- Ye Pengpeng
- Yimam Hassen Hamid
- Yip Paul
- Yonemoto Naohiro
- Yoon Seok-Jun
- Yotebieng Marcel
- Younis Mustafa Z.
- Zaidi Zoubida
- Zaki Maysaa El Sayed
- Zegeye Elias Asfaw
- Zenebe Zerihun Menlkalew
- Zhang Xueying
- Zhou Maigeng
- Zipkin Ben
- Zodpey Sanjay
- Zuhlke Liesl Joanna
- Ärnlöv Johan
- Publication venue
- Publication date
- 01/01/2017
- Field of study
As mortality rates decline, life expectancy increases, and populations age, non-fatal outcomes of diseases and injuries are becoming a larger component of the global burden of disease. The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of prevalence, incidence, and years lived with disability (YLDs) for 328 causes in 195 countries and territories from 1990 to 2016
Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
- Author
- Abajobir Amanuel Alemu
- Abate Kalkidan Hassen
- Abbafati Cristiana
- Abbas Kaja M.
- Abd-Allah Foad
- Abdulkader Rizwan Suliankatchi
- Abdulle Abdishakur M.
- Abebo Teshome Abuka
- Abera Semaw Ferede
- Aboyans Victor
- Abu-Raddad Laith J.
- Ackerman Ilana N.
- Adedeji Isaac A.
- Adedji
- Adetokunboh Olatunji
- Afshin Ashkan
- Aggarwal Rakesh
- Agrawal Anurag
- Agrawal Sutapa
- Ahmed Muktar Beshir
- Aichour Amani Nidhal
- Aichour Ibtihel
- Aichour Miloud Taki Eddine
- Aiyar Sneha
- Akinyemiju Tomi F.
- Akseer Nadia
- Al Lami Faris Hasan
- Al-Aly Ziyad
- Al-Maskari Fatma
- Al-Raddadi Rajaa
- Alahdab Fares
- Alam Khurshid
- Alam Noore
- Alam Tahiya
- Alasfoor Deena
- Alene Kefyalew Addis
- Ali Raghib
- Alizadeh-Navaei Reza
- Alkaabi Juma M.
- Alkerwi Ala'a
- Alla François
- Allebeck Peter
- Allen Christine
- Almazroa Mohammad Abdulaziz
- Alsharif Ubai
- Alsowaidi Shirina
- Althouse Benjamin M.
- Altirkawi Khalid A.
- Alvis-Guzman Nelson
- Amare Azmeraw T.
- Amini Erfan
- Ammar Walid
- Amoako Yaw Ampem
- Ansha Mustafa Geleto
- Antonio Carl Abelardo T.
- Anwari Palwasha
- Arora Megha
- Artaman Al
- Arthur Avokpaho Euripide Frinel G.
- Aryal Krishna Kumar
- Asgedom Solomon W.
- Atey Tesfay Mehari
- Atnafu Niguse Tadele
- Avila-Burgos Leticia
- Awasthi Ashish
- Awasthi Shally
- Azarpazhooh Mahmoud Reza
- Azzopardi Peter
- Babalola Tesleem Kayode
- Bacha Umar
- Badawi Alaa
- Balakrishnan Kalpana
- Bannick Marlena S.
- Barac Aleksandra
- Barker-Collo Suzanne L.
- Barquera Simon
- Barrero Lope H.
- Basu Sanjay
- Battista Robert
- Battle Katherine E.
- Baune Bernhard T.
- Bazargan-Hejazi Shahrzad
- Beardsley Justin
- Bedi Neeraj
- Bekele Bayu Begashaw
- Bell Michelle L.
- Bennett Derrick A.
- Bennett James R.
- Bensenor Isabela M.
- Benson Jennifer
- Berhane Adugnaw
- Berhe Derbew Fikadu
- Bernabé Eduardo
- Betsu Balem Demtsu
- Beuran Mircea
- Beyene Addisu Shunu
- Bhansali Anil
- Bhatt Samir
- Bhutta Zulfqar A.
- Biadgilign Sibhatu
- Bicer Burcu Kucuk
- Bienhof Kelly
- Bikbov Boris
- Birungi Charles
- Biryukov Stan
- Bisanzio Donal
- Bizuayehu Habtamu Mellie
- Blyth Fiona M.
- Boneya Dube Jara
- Bose Dipan
- Bou-Orm Ibrahim R.
- Bourne Rupert R. A.
- Brainin Michael
- Brayne Carol E. G.
- Brazinova Alexandra
- Breitborde Nicholas J. K.
- Briant Paul S.
- Britton Gabrielle
- Brugha Traolach S.
- Bryane
- Buchbinder Rachelle
- Bulto Lemma Negesa Bulto
- Bumgarner Blair
- Butt Zahid A.
- Bärnighausen Till
- Béjot Yannick
- Cahuana-Hurtado Lucero
- Cameron Ewan
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- Yu Chuanhua
- Zaidi Zoubida
- Zaki Maysaa El Sayed
- Zegeye Elias Asfaw
- Zenebe Zerihun Menlkalew
- Zhang Xueying
- Zheng Yingfeng
- Zhou Maigeng
- Zipkin Ben
- Zodpey Sanjay
- Zoeckler Leo
- Zuhlke Liesl Joanna
- Ärnlöv Johan
- Publication venue
- Publication date
- 01/01/2017
- Field of study
BACKGROUND: Measurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and identify specific needs for resource allocation in research, policy development, and programme decision making. Using the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we drew from two widely used summary measures to monitor such changes in population health: disability-adjusted life-years (DALYs) and healthy life expectancy (HALE). We used these measures to track trends and benchmark progress compared with expected trends on the basis of the Socio-demographic Index (SDI).
METHODS: We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 for all-cause mortality, cause-specific mortality, and non-fatal disease burden to derive HALE and DALYs by sex for 195 countries and territories from 1990 to 2016. We calculated DALYs by summing years of life lost and years of life lived with disability for each location, age group, sex, and year. We estimated HALE using age-specific death rates and years of life lived with disability per capita. We explored how DALYs and HALE differed from expected trends when compared with the SDI: the geometric mean of income per person, educational attainment in the population older than age 15 years, and total fertility rate.
FINDINGS: The highest globally observed HALE at birth for both women and men was in Singapore, at 75·2 years (95% uncertainty interval 71·9-78·6) for females and 72·0 years (68·8-75·1) for males. The lowest for females was in the Central African Republic (45·6 years [42·0-49·5]) and for males was in Lesotho (41·5 years [39·0-44·0]). From 1990 to 2016, global HALE increased by an average of 6·24 years (5·97-6·48) for both sexes combined. Global HALE increased by 6·04 years (5·74-6·27) for males and 6·49 years (6·08-6·77) for females, whereas HALE at age 65 years increased by 1·78 years (1·61-1·93) for males and 1·96 years (1·69-2·13) for females. Total global DALYs remained largely unchanged from 1990 to 2016 (-2·3% [-5·9 to 0·9]), with decreases in communicable, maternal, neonatal, and nutritional (CMNN) disease DALYs offset by increased DALYs due to non-communicable diseases (NCDs). The exemplars, calculated as the five lowest ratios of observed to expected age-standardised DALY rates in 2016, were Nicaragua, Costa Rica, the Maldives, Peru, and Israel. The leading three causes of DALYs globally were ischaemic heart disease, cerebrovascular disease, and lower respiratory infections, comprising 16·1% of all DALYs. Total DALYs and age-standardised DALY rates due to most CMNN causes decreased from 1990 to 2016. Conversely, the total DALY burden rose for most NCDs; however, age-standardised DALY rates due to NCDs declined globally.
INTERPRETATION: At a global level, DALYs and HALE continue to show improvements. At the same time, we observe that many populations are facing growing functional health loss. Rising SDI was associated with increases in cumulative years of life lived with disability and decreases in CMNN DALYs offset by increased NCD DALYs. Relative compression of morbidity highlights the importance of continued health interventions, which has changed in most locations in pace with the gross domestic product per person, education, and family planning. The analysis of DALYs and HALE and their relationship to SDI represents a robust framework with which to benchmark location-specific health performance. Country-specific drivers of disease burden, particularly for causes with higher-than-expected DALYs, should inform health policies, health system improvement initiatives, targeted prevention efforts, and development assistance for health, including financial and research investments for all countries, regardless of their level of sociodemographic development. The presence of countries that substantially outperform others suggests the need for increased scrutiny for proven examples of best practices, which can help to extend gains, whereas the presence of underperforming countries suggests the need for devotion of extra attention to health systems that need more robust support.
FUNDING: Bill & Melinda Gates Foundation
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease
- Author
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- Publication venue
- Springer Science and Business Media LLC
- Publication date
- 01/04/2024
- Field of study
One in ten severe acute respiratory syndrome coronavirus 2 infections result in prolonged symptoms termed long coronavirus disease (COVID), yet disease phenotypes and mechanisms are poorly understood1. Here we profiled 368 plasma proteins in 657 participants ≥3 months following hospitalization. Of these, 426 had at least one long COVID symptom and 233 had fully recovered. Elevated markers of myeloid inflammation and complement activation were associated with long COVID. IL-1R2, MATN2 and COLEC12 were associated with cardiorespiratory symptoms, fatigue and anxiety/depression; MATN2, CSF3 and C1QA were elevated in gastrointestinal symptoms and C1QA was elevated in cognitive impairment. Additional markers of alterations in nerve tissue repair (SPON-1 and NFASC) were elevated in those with cognitive impairment and SCG3, suggestive of brain–gut axis disturbance, was elevated in gastrointestinal symptoms. Severe acute respiratory syndrome coronavirus 2-specific immunoglobulin G (IgG) was persistently elevated in some individuals with long COVID, but virus was not detected in sputum. Analysis of inflammatory markers in nasal fluids showed no association with symptoms. Our study aimed to understand inflammatory processes that underlie long COVID and was not designed for biomarker discovery. Our findings suggest that specific inflammatory pathways related to tissue damage are implicated in subtypes of long COVID, which might be targeted in future therapeutic trials
SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination
- Author
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- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2023
- Field of study
BACKGROUND: Most studies of immunity to SARS-CoV-2 focus on circulating antibody, giving limited insights into mucosal defences that prevent viral replication and onward transmission. We studied nasal and plasma antibody responses one year after hospitalisation for COVID-19, including a period when SARS-CoV-2 vaccination was introduced. METHODS: In this follow up study, plasma and nasosorption samples were prospectively collected from 446 adults hospitalised for COVID-19 between February 2020 and March 2021 via the ISARIC4C and PHOSP-COVID consortia. IgA and IgG responses to NP and S of ancestral SARS-CoV-2, Delta and Omicron (BA.1) variants were measured by electrochemiluminescence and compared with plasma neutralisation data. FINDINGS: Strong and consistent nasal anti-NP and anti-S IgA responses were demonstrated, which remained elevated for nine months (p < 0.0001). Nasal and plasma anti-S IgG remained elevated for at least 12 months (p < 0.0001) with plasma neutralising titres that were raised against all variants compared to controls (p < 0.0001). Of 323 with complete data, 307 were vaccinated between 6 and 12 months; coinciding with rises in nasal and plasma IgA and IgG anti-S titres for all SARS-CoV-2 variants, although the change in nasal IgA was minimal (1.46-fold change after 10 months, p = 0.011) and the median remained below the positive threshold determined by pre-pandemic controls. Samples 12 months after admission showed no association between nasal IgA and plasma IgG anti-S responses (R = 0.05, p = 0.18), indicating that nasal IgA responses are distinct from those in plasma and minimally boosted by vaccination. INTERPRETATION: The decline in nasal IgA responses 9 months after infection and minimal impact of subsequent vaccination may explain the lack of long-lasting nasal defence against reinfection and the limited effects of vaccination on transmission. These findings highlight the need to develop vaccines that enhance nasal immunity. FUNDING: This study has been supported by ISARIC4C and PHOSP-COVID consortia. ISARIC4C is supported by grants from the National Institute for Health and Care Research and the Medical Research Council. Liverpool Experimental Cancer Medicine Centre provided infrastructure support for this research. The PHOSP-COVD study is jointly funded by UK Research and Innovation and National Institute of Health and Care Research. The funders were not involved in the study design, interpretation of data or the writing of this manuscript
The North Carolina State Government Website Archives: A case study of an American government Web archiving project
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Collaborations Between Multicultural Educators and Archivists: Engaging Students with Multicultural History Through Archival Research Projects
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Capture and release: cataloguing cultural heritage at Marrickville Library and History Services
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
- …