Adapting clinical guidelines to take account of multimorbidity

Most people with a chronic condition have multimorbidity, but clinical guidelines almost entirely focus on single conditions. It will never be possible to have good evidence for every possible combination of conditions, but guidelines could be made more useful for people with multimorbidity if they were delivered in a format that brought together relevant recommendations for different chronic conditions and identified synergies, cautions, and outright contradictions. We highlight the problem that multimorbidity poses to clinicians and patients using guidelines for single conditions and propose ways of making them more useful for people with multimorbidity

Evolutionary Associations Of Brood Parasitic Finches (Vidua) And Their Host Species: Analyses Of Mitochondrial Dna Restriction Sites

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/137614/1/evo01655.pd

A Study of Two Facultative Lagoons for Municipal Wastewater Treatment in Iowa

Two 2-celled facultative lagoons, comparable in design and serving small communities in rural Iowa, were studied for seven consecutive summer weeks. Chemical and physical parameters of water quality were monitored in samples taken from influent and effluent structures and at two depths and three to six locations in each cell. The composition and density of the phytoplankton was monitored, and total and fecal coliform counts were made. A diurnal study showed wide fluctuations in the chemical composition of influent wastewater. The quality of effluent water was comparable for the two lagoons although one was loaded to design capacity and the other to half capacity. During the study period, both lagoons met the Iowa standards and approached the EPA standards

Variation of mohair staple length across Angora goat fleeces : implications for animal selection and fleece evaluation

The present study aimed to determine how the average mohair staple length (SL) differences between nine sampling sites vary between sex and flock, to identify differences in SL variability between sampling sites as a result of between-animal and between-sire variability and to determine SL correlations between sampling sites in between-animal and between-sire variability. Australian Angora goats (n=301) from two farms in southern Australia were sampled at 12 and 18 months of age at nine sites (mid side, belly, brisket, hind flank, hip, hock, mid back, neck and shoulder). Staples were taken prior to shearing at skin level and stretched SL determined. For each shearing, differences in SL between sampling sites, how these differences were affected by farm, sex and sire, and the covariance between sites for sire and individual animal effects were investigated by restricted maximum likelihood (REML) analyses. The median mid-side SL at 12 and 18 months of age was 110 and 130 mm, respectively, but the actual range in mid-side SL was 65&ndash;165 mm. There was an anterior&ndash;posterior decline in SL with the hock being particularly short. There was no evidence that the between-site correlation of the sire effects differed from 1, indicating that genetic selection for SL at one site will be reflected in SL over the whole fleece. However, low heritabilities of SL at the hock, belly and brisket or at any site at 12 months of age were obtained. There was more variability between sites than between sires, but the between-animal variation was greater. The hip and mid-back sites can be recommended for within-flock (culling) and genetic selection for SL due to their low sampling variability, moderate heritability and ease of location. <br /

On the order of a non-abelian representation group of a slim dense near hexagon

We show that, if the representation group $R$ of a slim dense near hexagon $S$ is non-abelian, then $R$ is of exponent 4 and $|R|=2^{\beta}$, $1+NPdim(S)\leq \beta\leq 1+dimV(S)$, where $NPdim(S)$ is the near polygon embedding dimension of $S$ and $dimV(S)$ is the dimension of the universal representation module $V(S)$ of $S$. Further, if $\beta =1+NPdim(S)$, then $R$ is an extraspecial 2-group (Theorem 1.6)

Towards a Macroscopic Modelling of the Complexity in Traffic Flow

We present a macroscopic traffic flow model that extends existing fluid-like models by an additional term containing the second derivative of the safe velocity. Two qualitatively different shapes of the safe velocity are explored: a conventional Fermi-type function and a function exhibiting a plateau at intermediate densities. The suggested model shows an extremely rich dynamical behaviour and shows many features found in real-world traffic data.Comment: submitted to Phys. Rev.

From respect to reburial: negotiating pagan interest in prehistoric human remains in Britain, through the Avebury consultation

The recent Avebury Consultation on reburial has drawn considerable public and professional attention to the issue of pagan calls for respect towards the care of human remains. Our work has pointed to the importance of archaeologists and others engaging seriously and respectfully with pagans as significant stakeholders in our heritage. The Avebury Reburial Consultation suggests this dialogue is increasing in strength, but we identify problems in the process. We focus here on approaches to the prehistoric dead and worldviews enabling communication from which calls or ‘claims’ for the reburial of prehistoric pagan human remains, versus their retention for scientific study, are articulated; frameworks for assessing and adjudicating such ‘claims’; and implications for the interest groups concerned. We argue that room must be made for philosophical debate and the emotional and spiritual views of pagans, in order to improve dialogue, develop common ground, and enable participatory decision-making and situational pragmatism

The Balian-Br\'ezin Method in Relativistic Quantum Mechanics

The method suggested by Balian and Br\'ezin for treating angular momentum reduction in the Faddeev equations is shown to be applicable to the relativistic three-body problem.Comment: 14 pages in LaTe

WATER REPELLENT RENDERINGS FOR THE DAMP-PROOFING OF MONUMENTS

The global transitional justice tool kit—involving the use of criminal prosecutions, amnesties, and other mechanisms to address past human rights abuse—has become a primary means for thwarting future human rights violations and consolidating democracy. Nevertheless, evidence on the consequences of transitional justice remains mixed and amenable to contradictory interpretations. Existing studies fail to adequately address issues of selection, the difference between short- and long-term effects of transitional justice mechanisms, and qualitative and quantitative differences in state practices. This article uses a new database of transitional justice mechanisms to address these concerns and test propositions from realist, constructivist, and holistic approaches to this set of policy issues. We find, among other things, that prosecutions increase physical integrity protections, while amnesties increase the protection of civil and political rights. Our analysis suggests that different transnational justice policies each play a potentially positive, but distinct, role in new democracies and in decreasing violations of human rights