110 research outputs found
The efficacy of itraconazole against systemic fungal infections in neutropenic patients : a randomised comparative study with amphotericin B
Contains fulltext :
4533.pdf (publisher's version ) (Open Access
Meeting highlight : 3rd Biannual meeting : "Trends in invasive fungal infection"
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20632___.PDF (publisher's version ) (Open Access
Practical modalities for prevention of fungal infections in cancer patients
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24681___.PDF (publisher's version ) (Open Access
Prophylaxis and aspergillosis--has the principle been proven?
Contains fulltext :
53158.pdf (publisher's version ) (Open Access
Timely intervention for invasive fungal disease: should the road now lead to the laboratory instead of the pharmacy?
Contains fulltext :
81115.pdf (publisher's version ) (Open Access
Preventative use of antifungal drugs in patients treated for cancer.
Item does not contain fulltextProphylactic use of antifungal compounds has more or less become standard clinical practice for patients who are treated for a haematological malignancy. However, apart from the prevention of infections by Candida species in bone marrow transplant recipients and a possible reduction in invasive aspergillosis in high-risk patients, there is little evidence to justify this approach. Antifungals ought to be administered to patients on their perceived individual risk and better studies should be conducted to provide a more rational basis for our clinical decisions. Results of studies in specific populations should not be used to create guidelines for other patient groups or general populations. Antifungals are potentially toxic and overuse might be associated with unnecessary direct and indirect drug-related costs
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