5 research outputs found
Surface-enhanced Raman scattering biomedical applications of plasmonic colloidal particles
This review article presents a general view of the recent progress in the fast developing area of surface-enhanced Raman scattering spectroscopy as an analytical tool for the detection and identification of molecular species in very small concentrations, with a particular focus on potential applications in the biomedical area. We start with a brief overview of the relevant concepts related to the choice of plasmonic nanostructures for the design of suitable substrates, their implementation into more complex materials that allow generalization of the method and detection of a wide variety of (bio)molecules and the strategies that can be used for both direct and indirect sensing. In relation to indirect sensing, we devote the final section to a description of SERS-encoded particles, which have found wide application in biomedicine (among other fields), since they are expected to face challenges such as multiplexing and high-throughput screening
Growth of Sharp Tips on Gold Nanowires Leads to Increased Surface-Enhanced Raman Scattering Activity
We report the formation of gold nanoparticles with a novel
and useful morphology, comprising nanowires fully covered with sharp
tips (thorned nanowires). The synthesis is based on a seeded-growth
approach based the rapid overgrowth of ultrathin gold wires in <i>N</i>,<i>N</i>-dimethylformamide, in the presence
of poly(vinylpyrrolidone). The process allows a fine control over
the thickness of the final wires, as well as the tunability of the
number and sharpness of the thorns. These new plasmonic nanostructures
display extremely strong optical enhancing properties and can be readily
used as platforms for SERS and for integration in ultrasensitive optical
devices
Growth of Sharp Tips on Gold Nanowires Leads to Increased Surface-Enhanced Raman Scattering Activity
We report the formation of gold nanoparticles with a novel
and useful morphology, comprising nanowires fully covered with sharp
tips (thorned nanowires). The synthesis is based on a seeded-growth
approach based the rapid overgrowth of ultrathin gold wires in <i>N</i>,<i>N</i>-dimethylformamide, in the presence
of poly(vinylpyrrolidone). The process allows a fine control over
the thickness of the final wires, as well as the tunability of the
number and sharpness of the thorns. These new plasmonic nanostructures
display extremely strong optical enhancing properties and can be readily
used as platforms for SERS and for integration in ultrasensitive optical
devices