Diagnosis and Treatment of Gonorrhea

The various methods for diagnosis of gonorrhea are reviewed. Gram-stained smear of urethral exudate in the mate is appropriate, but for the female emphasis is placed on the use of culture on Thayer-Martin medium. Currently effective modalities of treatment are detailed, pointing out that higher doses of antibiotics are generally required for females with pelvic inflammatory disease than for males with acute gonococcal urethritis. The necessity for follow-up is also discussed

Pleural Effusion in Michigan Caused by Coccidioides Immitis After Travel to an Endemic Area

Primary coccidioidal disease is rarely diagnosed in the midwest in the nonimmunocompromised host. Since coast-to-coast travel is common today, many patients may become exposed to Coccidioides immitis while traveling in endemic areas. We present a case of acute coccidioidal pleural effusion in a Michigan woman who had recently visited northeastern Arizona. Her travel history was the single most important factor in the eventual diagnosis of coccidioidal pleural effusion

Small Cell Carcinoma of the Lung in the Intensive Care Unit

The outcome of 29 patients with a diagnosis of small cell carcinoma of the lung admitted to the medical intensive care unit (MICU) from 1980 through 1984 was reviewed retrospectively. Respiratory failure was the most common admitting diagnosis (23 patients [80%]). followed by cardiopulmonary arrest (three patients [10%]), and hypotension (three patients [10%] ). Only five patients survived to leave the MICU, and only two of these patients lived longer than two months after MICU discharge. Of the features examined, the absence of sepsis was the only statistically significant predictor of MICU survival. Treatment of the malignancy did not appear to alter the outcome even if endobronchial tumor was thought to be a contributor to respiratory failure. The outlook of patients with small cell carcinoma of the lung admitted to the MICU is grim, and limitation of care should be considered in many of these patients

One size fits all? Calibrating an ocean biogeochemistry model for different circulations

Global biogeochemical ocean models are often tuned to match the observed distributions and fluxes of inorganic and organic quantities. This tuning is typically carried out “by hand”. However, this rather subjective approach might not yield the best fit to observations, is closely linked to the circulation employed and is thus influenced by its specific features and even its faults. We here investigate the effect of model tuning, via objective optimisation, of one biogeochemical model of intermediate complexity when simulated in five different offline circulations. For each circulation, three of six model parameters have been adjusted to characteristic features of the respective circulation. The values of these three parameters – namely, the oxygen utilisation of remineralisation, the particle flux parameter and potential nitrogen fixation rate – correlate significantly with deep mixing and ideal age of North Atlantic Deep Water (NADW) and the outcrop area of Antarctic Intermediate Waters (AAIW) and Subantarctic Mode Water (SAMW) in the Southern Ocean. The clear relationship between these parameters and circulation characteristics, which can be easily diagnosed from global models, can provide guidance when tuning global biogeochemistry within any new circulation model. The results from 20 global cross-validation experiments show that parameter sets optimised for a specific circulation can be transferred between similar circulations without losing too much of the model's fit to observed quantities. When compared to model intercomparisons of subjectively tuned, global coupled biogeochemistry–circulation models, each with different circulation and/or biogeochemistry, our results show a much lower range of oxygen inventory, oxygen minimum zone (OMZ) volume and global biogeochemical fluxes. Export production depends to a large extent on the circulation applied, while deep particle flux is mostly determined by the particle flux parameter. Oxygen inventory, OMZ volume, primary production and fixed-nitrogen turnover depend more or less equally on both factors, with OMZ volume showing the highest sensitivity, and residual variability. These results show a beneficial effect of optimisation, even when a biogeochemical model is first optimised in a relatively coarse circulation and then transferred to a different finer-resolution circulation model

Electron Capture at Very Small Scattering Angles from Atomic Hydrogen by 25-125-keV Protons

Differential cross sections for electron capture in collisions between protons and hydrogen atoms have been experimentally determined for incident proton energies of 25, 60, and 125 keV in the center-of-mass scattering-angle range of 0-3 mrad. The experimental results compare more favorably with the results of both a multistate and a two-state calculation than with the results of a continuum distorted-wave-approximation calculation. There is no evidence of a Jackson-Schiff-type minimum

Empirical Challenges in Organizational Aesthetics Research: Towards a Sensual Methodology

Despite growing scholarly interest in aesthetic dimensions of organizational life, there is a lack of literature expressly engaging with the methodological mechanics of 'doing aesthetics research'. This article addresses that gap. It begins with an overview of the conceptual idiosyncrasies of 'aesthetics' as a facet of human existence and maps out the challenges these pose for empirical research methodology. A review of methodological approaches adopted to date in empirical studies of organizational aesthetics is then presented. The remainder of the article draws on the author's experiences and suggests methods and techniques to address both conceptual and practical challenges encountered during the execution of an organizational aesthetics research project. The article calls for a firmer focus on the aesthetic experiences of organizational members in addition to those of researchers and concludes with some suggestions as to the future of such 'sensual methodologies' </jats:p

Elastic Differential Cross Sections for Small-Angle Scattering of 25-, 50-, and 100-keV Protons by Helium Atoms

The first measurements of elastic differential cross sections have been carried out for 25-, 50-, and 100-keV protons scattered through very small angles by helium atoms. The University of Missouri Rolla energy-loss spectrometer provided the required high angular resolution and also separated the elastically scattered ions from the inelastically scattered ions. The data are compared to our Born, Glauber, and classical calculations as well as a four-state calculation. All of the measured elastic differential cross sections are more sharply peaked than theory for the smallest scattering angles. At the larger scattering angles all of the measured elastic differential cross sections are below the theoretical calculations. However, if the classical calculation is interpreted as a total differential scattering cross section, it compares well with our estimate of the sum of the elastic, charge-transfer, and inelastic differential cross sections

Angular Differential and Total Cross Sections for the Excitation of Atomic Hydrogen to Its n=2 Level by 25-150-kev Hydrogen Molecular Ions

Experimentally and theoretically determined differential and total cross sections are reported for excitation of atomic hydrogen to its n=2 level by 25-150-keV hydrogen molecular ions. The differential cross sections decrease 3-4 orders of magnitude over the measured center-of-mass scattering-angular range from 0 to 4.5 mrad. The results of a first Born approximation and two other theoretical calculations based upon the Glauber approximation are presented and compared with the experimental results. Both calculations based on the Glauber approximation agree fairly well with the experimental results. The Born approximation agrees moderately well with the experimental results at the very small scattering angles but is well below the experimental results at the larger scattering angles. None of the theoretical calculations presented agree well with the total cross section. However, the results for the total cross section of the two calculations based on the Glauber approximation agree with the experimental results in curve shape better than the Born-approximation results

Angular Differential and Total Cross Sections for the Excitation of Atomic Hydrogen to Its n=2 State by Helium Ions

Differential cross sections for 15-100 keV He+ excitation of atomic hydrogen to its n=2 level have been determined for c.m. angles from 0 to 8 mrad. The differential cross sections are obtained from an analysis of the angular distribution of the scattered ions which have lost an energy corresponding to the excitation of the target to its n=2 level. The shape of the differential cross section changes rapidly with increasing incident energy. At 15 keV, the differential cross section falls off by a factor of 5 in 6 mrad. At 100 keV, the differential cross section decreases by nearly six orders of magnitude in the same angular range. The higher-energy results are in fair agreement with a recent symmetrized first-order Glauber approximation calculation of the process. Total cross section results are given for the same process in the 15-200 keV range

Differential Cross Sections for Electron Capture from Helium by 25- to 100-keV Incident Protons

Experimentally and theoretically determined differential cross sections are reported for electron capture in collisions of protons with helium atoms for incident proton energies of 25, 30, 50, and 100 keV and for center-of-mass scattering angles of 0.0 to 2.0 mrad. The magnitudes of the experimentally determined differential cross sections decrease from 10-10 to 10-12 cm2/sr within the 0.0-0.8-mrad range of the center-of-mass scattering angle. At approximately 0.8 mrad a distinct change in the slope of the differential cross section is observed. The experimental results which are for capture into all bound states of hydrogen are compared with the theoretical results of a calculation for capture into the ground state using the two-state two-center atomic expansion method in the eikonal approximation. Good agreement between the theoretical and the experimental results is obtained with a static potential which accounts for screening of the helium nucleus by a single passive electron