Association of high polymegathism (increased variation of cell size) in study population (n = 468).

*<p> = test for trend.</p>§<p>Adjusted for all other variables in µodel.</p

Multivariable models to demonstrate association of endothelial cell parameters in HIV-infected individuals (n = 217).

§<p>Adjusted for all other variables in model.</p>*<p> = test for trend.</p

Association of low endothelial cell density in study population (n = 468).

*<p> = test for trend.</p>§<p>Adjusted for all other variables in model.</p

Example of corneal endothelial cells captured by specular microscopy.

<p>A: Endothelial cells – density is 2454 cells/mm². B: Polymegathism assessment – measurement of cell size. C: Pleomorphism assessment – proportion of cells that are hexagonal.</p

Characteristics of study participants.

*<p>ART =  Anti-retroviral therapy</p

Estimated Difference in Telomere Length^* Associated With Education and Childhood SES Measures^†.

*<p>Telomere length measured as relative T/S ratio multiplied by 10.</p>†<p>Analysis samples are weighted to members of the baseline sample who were still alive at wave 5 and all analyses adjusted for gender and plate.</p>‡<p>Unstandardized regression coefficients.</p

Estimated Difference in Telomere Length^* Associated With Measures of SES Over Time^†.

*<p>Telomere length measured as relative T/S ratio multiplied by 10.</p>†<p>Analysis samples are weighted to members of the baseline sample who were still alive at wave 5 and all analyses adjusted for gender and plate.</p>‡<p>Unstandardized regression coefficients.</p

Association of endothelial cell parameters with HIV status.

*<p> = p-value: test for trend.</p>**<p>Adjusted for age, gender, UV exposure, BMI, alcohol and cigarette smoking status, any history of an eye condition.</p

Characteristics of Study Members, Including Mean Telomere Lengths^*.

*<p>All telomere length means reported are unadjusted.</p>¥<p>The high number of missing values reported here is due to the relocation of respondents to non-Scottish locations.</p>†<p>Other includes: full-time education, short-term sick, government training scheme, maternity leave or other description not included here.</p>‡<p>Advanced  =  University degree, Level 5 vocational qualification, nursing qualification, teaching qualification, or equivalent.</p><p>Basic  =  O-Levels, GCSEs, Standard Grades, A-Levels, Highers, HNC/HND, recognized trade apprenticeship, or equivalent.</p><p>None  =  none of the above.</p

Multivariate model outcome for eGFR at 6 months.

<p>The model approaches statistical significance using the strict Bonferroni correction (p = 0.021).</p