5,620 research outputs found
CIT-5: a high-silica zeolite with 14-ring pores
The synthesis and structure of a new zeolite, CIT-5 (California Institute of Technology Number Five), is described, which possesses one-dimensional pores comprised of 14 T-atoms (tetrahedrally coordinated silicon or aluminium atoms)
Addressing Employee Lawsuits
[Excerpt] For months you tried to save this employee. You gave him numerous second chances, you gave him a performance improvement plan, and you even put him on probation. Finally, after all the warnings, the low productivity, and the time and effort, you have no choice but to let the employee go. You agonized over the decision but knew it was right. Imagine your surprise when you received a letter in the mail today accusing you and your company of disability discrimination! You did not even know the employee was disabled. You are faced with the reality: All managers are, at one time or another, accused of discrimination. The purpose of this chapter is to help you respond to this complaint by: (1) defining the law; (2) explaining how discrimination claims are adjudicated; (3) discussing the Americans with Disabilities Act and sexual harassment; and (4) advising employers in the hospitality industry on how to avoid liability
A Framework for Establishing Restoration Goals for Contaminated Ecosystems
This article represents 1 of 6 articles in the special series “Restoration of Impaired Ecosystems: An Ounce of Prevention or a Pound of Cure?” The articles result from a Technical Workshop organized by SETAC and the Society for Ecological Restoration, held June 2014 in Jackson, Wyoming, that focused on advancing the practice of restoring ecosystems that have been contaminated or impaired from industrial activities.As natural resources become increasingly limited, the value of restoring contaminated sites, both terrestrial and aquatic, becomes increasingly apparent. Traditionally, goals for remediation have been set before any consideration of goals for ecological restoration. The goals for remediation have focused on removing or limiting contamination whereas restoration goals have targeted the ultimate end use. Here, we present a framework for developing a comprehensive set of achievable goals for ecological restoration of contaminated sites to be used in concert with determining goals for remediation. This framework was developed during a Society of Environmental Toxicology and Chemistry (SETAC) and Society of Ecological Restoration (SER) cosponsored workshop that brought together experts from multiple countries. Although most members were from North America, this framework is designed for use internationally. We discuss the integration of establishing goals for both contaminant remediation and overall restoration, and the need to include both the restoration of ecological and socio-cultural-economic value in the context of contaminated sites. Although recognizing that in some countries there may be regulatory issues associated with contaminants and clean up, landscape setting and social drivers can inform the restoration goals. We provide a decision tree support tool to guide the establishment of restoration goals for contaminated ecosystems. The overall intent of this decision tree is to provide a framework for goal setting and to identify outcomes achievable given the contamination present at a site. Integr Environ Assess Manag 2016;12:264–272. 2015 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals, Inc. on behalf of Society of Environmental Toxicology & Chemistry (SETAC
Systematic Study of Two-Pion Production in NN Collisions -- from Single-Baryon to Di-Baryon Excitations
The two-pion production in nucleon-nucleon collisions has been studied by
exclusive and kinematically complete experiments from threshold up to =
1.36 GeV at CELSIUS-WASA. At near-threshold energies the total and differential
distributions for the and channels are dominated by
Roper excitation and its decay into and channels. At beam
energies 1.1 GeV the excitation governs the two-pion
production process. In the channel evidence is found for the
excitation of a higher-lying I=3/2 resonance, favorably the . The
isovector fusion processes leading to the deuteron and to quasi-stable He,
respectively, %with the production of an isovector pion-pair exhibit no or only
a modest ABC-effect, {\it i.e.} low-mass enhancement in the -invariant
mass spectrum, and can be described by conventional -channel
excitation. On the other hand, the isoscalar fusion process to the deuteron
%with the production of an isoscalar pion-pair exhibits a dramatic ABC-effect
correlated with a narrow resonance-like energy dependence in the total cross
section with a width of only 50 MeV and situated at a mass 90 MeV below the
mass.Comment: Proceedings HADRON0
Characterisation of FUT4 and FUT6 α-(1 → 2)-fucosyltransferases reveals that absence of root arabinogalactan fucosylation increases Arabidopsis root growth salt sensitivity.
Plant type II arabinogalactan (AG) polysaccharides are attached to arabinogalactan proteins (AGPs) at hydroxyproline residues, and they are very diverse and heterogeneous structures. The AG consists of a β-(1 → 3)-linked galactan backbone with β-(1 → 6)-galactan side chains that are modified mainly with arabinose, but they may also contain glucuronic acid, rhamnose or other sugars. Here, we studied the positions of fucose substitutions in AGPs, and we investigated the functions of this fucosylation. Monosaccharide analysis of Arabidopsis leaf AGP extracts revealed a significant reduction in L-Fucose content in the fut4 mutant, but not in the fut6 mutant. In addition, Fucose was reduced in the fut4 mutant in root AGP extracts and was absent in the fut4/fut6 mutant. Curiously, in all cases reduction of fucose was accompanied with a reduction in xylose levels. The fucosylated AGP structures in leaves and roots in wild type and fut mutant plants were characterised by sequential digestion with AG specific enzymes, analysis by Polysaccharide Analysis using Carbohydrate gel Electrophoresis, and Matrix Assisted Laser Desorption/Ionisation (MALDI)-Time of Flight Mass spectrometry (MS). We found that FUT4 is solely responsible for the fucosylation of AGPs in leaves. The Arabidopsis thaliana FUT4 and FUT6 genes have been previously proposed to be non-redundant AG-specific fucosyltransferases. Unexpectedly, FUT4 and FUT6 enzymes both fucosylate the same AGP structures in roots, suggesting partial redundancy to each other. Detailed structural characterisation of root AGPs with high energy MALDI-Collision Induced Dissociation MS and NMR revealed an abundant unique AG oligosaccharide structure consisting of terminal xylose attached to fucose. The loss of this structure in fut4/fut6 mutants explains the reduction of both fucose and xylose in AGP extracts. Under salt-stress growth conditions the fut4/fut6 mutant lacking AGP fucosylation exhibited a shorter root phenotype than wild type plants, implicating fucosylation of AGPs in maintaining proper cell expansion under these conditions
Analyzing Adherence to Prenatal Supplement: Does Pill Count Measure Up?
Objective. To determine if adherence as measured by pill count would show a significant association with serum-based measures of adherence.
Methods. Data were obtained from a prenatal vitamin D supplementation trial where subjects were stratified by race and randomized into three dosing groups: 400 (control), 2000, or 4000 IU vitamin D3/day. One measurement of adherence was obtained via pill counts remaining compared to a novel definition for adherence using serum 25-hydroxy-vitamin D (25-OH-D) levels (absolute change in 25(OH)D over the study period and the subject's steady-state variation in their 25(OH)D levels). A multivariate logistic regression model examined whether mean percent adherence by pill count was significantly associated with the adherence measure by serum metabolite levels.
Results. Subjects' mean percentage of adherence by pill count was not a significant predictor of adherence by serum metabolite levels. This finding was robust across a series of sensitivity analyses.
Conclusions. Based on our novel definition of adherence, pill count was not a reliable predictor of adherence to protocol, and calls into question how adherence is measured in clinical research. Our findings have implications regarding the determination of efficacy of medications under study and offer an alternative approach to measuring adherence of long half-life supplements/medications
Fv antibodies to aflatoxin B1 derived from a pre-immunized antibody phage display library system
The production and characterization of recombinant antibodies to aflatoxin B[SUB1] (AFB[SUB1]), a potent mycotoxin and carcinogen is described. The antibody fragments produced were then applied for use in a surface plasmon resonance-based biosensor (BIAcore), which measures biomolecular interactions in 'real-time'. Single chain Fv (scFv) antibodies were generated to aflatoxin B1 from an established phage display system, which incorporated a range of different plasmids for efficient scFv expression. The scFv's were used in the development of a competitive ELISA, and also for the development of surface plasmon resonance (SPR)-based inhibition immunoassays. They were found to be suitable for the detection of AFB[SUB1], in this format, with the assays being sensitive and reproducible
Ursinus College Alumni Journal, July 1953
President\u27s page • 135 degrees awarded at 83rd annual commencement • Rev. J. Alfred Kaye commencement speaker • Baccalaureate sermon delivered by Rev. Shaffer • Medical students accomplishment report • Dr. Lauer and Rev. Jeffers elected to Board of Directors • Sun Oil president speaks to business admin. students • Ursinus summer sessions open June 4 and July 23 • Dr. Johnson honored by Western Reserve • Open scholarships awarded to seven high school seniors • Sun shines on delightful Ursinus May Day • Five local alumni groups hold spring meetings • President Glassmoyer talks things over • Alumni president Kermit Black ill • Rain fails to dampen friendly spirit of Alumni Day • Portrait of Dr. Brownback presented to Ursinus • Montgomery County homes opened for women\u27s tour • Provident Mutual wants Ursinus grads • Marion Sis Bosler coaches Ursinus mermaids • Baseball squad has best record in 39 years • Dawkins takes a first in Middle Atlantics • Track resume for 1953 • Captain Kenney only veteran tennis player • Women\u27s softball team closes another undefeated season • Women\u27s tennis team wins five, loses four • News about ourselves • Necrology • John Manning honored in mathematical competition • Alumni association plans permanent class organizationhttps://digitalcommons.ursinus.edu/alumnijournal/1046/thumbnail.jp
Variability of the Spectral Energy Distribution of the Blazar S5 0716+714
The emission from blazars is known to be variable at all wavelengths. The
flux variability is often accompanied by spectral changes. Spectral energy
distribution (SED) changes must be associated with changes in the spectra of
emitting electrons and/or the physical parameters of the jet. Meaningful
modeling of blazar broadband spectra is required to understand the extreme
conditions within the emission region. Not only is the broadband SED crucial,
but also information about its variability is needed to understand how the
highest states of emission occur and how they differ from the low states. This
may help in discriminating between models. Here we present the results of our
SED modeling of the blazar S5 0716+714 during various phases of its activity.
The SEDs are classified into different bins depending on the optical brightness
state of the source.Comment: 4 pages, 3 figures, contributed talk presented at the conference
Multifrequency Variability of Blazars, Guangzhou, China, September 22-24,
2010. To appear in Journal of Astrophysics and Astronomy (JAA
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