277 research outputs found
Narrative Subversion of Acknowledgement and Denial within ex-Nazi Memoirs
HonorsJudaic StudiesUniversity of Michiganhttp://deepblue.lib.umich.edu/bitstream/2027.42/169407/3/mpattipa.pd
Multiple Fault Isolation in Redundant Systems
Fault diagnosis in large-scale systems that are products of modem technology present formidable challenges to manufacturers and users. This is due to large number of failure sources in such systems and the need to quickly isolate and rectify failures with minimal down time. In addition, for fault-tolerant systems and systems with infrequent opportunity for maintenance (e.g., Hubble telescope, space station), the assumption of at most a single fault in the system is unrealistic. In this project, we have developed novel block and sequential diagnostic strategies to isolate multiple faults in the shortest possible time without making the unrealistic single fault assumption
Model-Based Organization Analysis and Design for an ESG Organization
11th Command and Control Research and Technology Symposium (CCRTS), June 20-22, 2006, San Diego, C
Varijacija gena Ī²-tubulin izotip 1 u kodonu 167 i 200 odgovorna za rezistenciju Haemonchus contortus na benzimidazol iz ovaca uzgajanih u distriktu Krishna, AP, Indija.
A study was carried out for detection of single nucleotide polymorphisms at codon 167 and 200 of the Ī²-tubulin isotype 1 gene that are linked to BZ resistance of Haemonchus contortus in sheep. A total of 226 adult male worms were genotyped from different regions of Krishna district, Andhra Pradesh. Amplification of DNA from each worm by PCR, followed by semi-nested PCR, yielded an expected fragment of 488 bp product. The PCR product was subsequently digested with restriction endonuclease SnaBI and TaaI to detect mutation at codon 167 and 200 respectively. On digestion, three different fragment patterns were observed at codon 200, one with 215 bp, 206 bp and 67 bp (homozygous resistant; ārrā), the second with 282 bp, 215 bp, 206 bp and 67 bp (heterozygous; ārSā), and another with 282 bp and 206 bp fragment (homozygous susceptible; āSSā). No resistance allele (TAC) was evident at codon 167 in any worms including the worms that carried a susceptible allele (TTC) at codon 200. The overall genotype frequencies varied significantly (P<0.01) with respect to the Ī²-tubulin gene/TaaI locus in the study area. The frequency of ārSā (64.60%) genotypes was high compared to that of ārrā and āSSā genotypes. The genotype frequency for ārrā worms ranged from 6.25% to 31.82% among different regions. In general, the prevalence of BZ resistance allele was found to be significantly (P<0.01) higher (54.0%). Results revealed Ī²-tubulin isotype 1 polymorphism at codon 200 in H. contortus of sheep indicating the occurrence of resistance allele in the study area.Provedeno je istraživanje s ciljem otkrivanja polimorfizama pojedinaÄnih nukleotida u kodonu 167 i 200, Ī²-tubulin izotip 1 gena koji je povezan s otpornoÅ”Äu ovÄjeg parazita Haemonchus contortus prema benzimidazolu (BZ). Genotipizirano je ukupno je 226 odraslih muÅ”kih crva iz razliÄitih podruÄja distrikta Krishna, Andhra Pradesh. Umnažanje DNA iz svakoga crva pomoÄu PCR-a praÄeno je poluugniježÄenim PCR-om, Äime je proizveden oÄekivani fragment od 488 bp. PCR produkt potom je pomijeÅ”an s restrikcijskim endonukleazama SnaBI i TaaI radi otkrivanja mutacije u kodonu 167 i 200. U kodonu 200 opažena su tri razliÄita fragmenta, jedan s 215 bp, 206 bp i 67 bp (homozigotno rezistentan, ārrā), drugi s 282 bp, 215 bp, 206 bp i 67 bp (heterozigot, ārSā) i treÄi s 282 bp i 206 bp fragmentom (homozigotno sumnjiv, āSSā). Rezistentni alel (TAC) nije ustanovljen u kodonu 167 svih istraženih crva, ukljuÄujuÄi crve koji su nosili sumnjivi alel (TTC) u kodonu 200. Ukupna uÄestalost genotipova znatno je varirala (P<0,01) u odnosu na Ī²-tubulin gen/TaaI lokus istraženog podruÄja. UÄestalost genotipa ārSā (64,60 %) bila je visoka u usporedbi s uÄestaloÅ”Äu genotipova ārrā i āSSā. UÄestalost genotipa ārrā kod crva iz razliÄitih podruÄja kretala se u rasponu od 6,25 % do 31,82 %. OpÄenito, opažena je signifikantno (P<0,01) viÅ”a (54,0 %) prevalencija BZ rezistentnog alela. Rezultati potvrÄuju da polimorfizam kodona 200 u Ī²-tubulin izotip 1 genu ovÄjeg parazita H. contortus upuÄuje na pojavu rezistentnih alela u istraženim podruÄjima
Multiple Fault Isolation in Redundant Systems
Fault diagnosis in large-scale systems that are products of modern technology present formidable challenges to manufacturers and users. This is due to large number of failure sources in such systems and the need to quickly isolate and rectify failures with minimal down time. In addition, for fault-tolerant systems and systems with infrequent opportunity for maintenance (e.g., Hubble telescope, space station), the assumption of at most a single fault in the system is unrealistic. In this project, we have developed novel block and sequential diagnostic strategies to isolate multiple faults in the shortest possible time without making the unrealistic single fault assumption
Congruence of Human Organizations and Missions: Theory versus Data
1999 Command and Control Research and Technology Symposium (CCRTS), June 29 - July 1, 1999, U.S. Naval War College, Rhode IslandIn this paper, we present a methodology for quantifying the degree of fit between a mission and an
organization based on the closeness between the task structure (i.e., resource requirements and task
interdependence) and the DM-asset allocation across the organization (i.e., amount and distribution
of resource capabilities among DMs, and organizational processes). This closeness is based on
three main characteristics of organizational performance: workload balance, communication
requirements, and DM-DM dependence. These characteristics are affected, in turn, by the
interactions and interdependencies of the organizational processes and the demands of the mission
scenario. Invariably, coordination is essential to achieve good performance because the
information required for decisionmaking is often distributed. However, excessive DM-DM
communication and coordination are harmful to performance, since they increase the processing
workload/overhead that delays task execution. Performance improvements can be obtained by
changing the structure and processes of an organization to decrease the requisite coordination,
while balancing the levels of workload across the organization and reducing inter DM dependence.This work was supported by the Office of Naval Research under contract # N00014-00-1-0101
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