490 research outputs found
Assessment of aspirin resistance varies on a temporal basis in patients with ischaemic heart disease
Limited susceptibility of three different mouse (Mus musculus) lines to Porcine circovirus-2 infection and associated lesions
Porcine circovirus associated disease (PCVAD), a major global problem for pork producers, is characterized microscopically by depletion and histiocytic replacement of follicles in the lymphoid tissues. The objectives of this study were to determine 1) if Porcine circovirus-2 (PCV-2) inoculated mice (Mus musculus) can develop PCV-2 associated lymphoid lesions and serve as a model for PCVAD, and 2) if differences in PCV-2 host susceptibility exist among mice lines. Three groups (n = 48/group) of 4-wk-old male mice were used: BALB/c, C57BL/6, and C3H/HeJ. A 2 Ă 2 factorial analysis was designed for each group using PCV-2 inoculation and keyhole limpet hemocyanin in incomplete Freundâs adjuvant injections on day 0 and 7 as factors. Necropsies were performed on days 12, 17, 22, 27, 32, and 37. Serum samples collected at each necropsy tested negative for anti-IgG PCV-2 antibodies in all mice at all time points by 2 different PCV-2 enzyme-linked immunosorbent assays (ELISA). The PCV-2 DNA was detected by polymerase chain reaction (PCR) in 93% (100/108) of tissues and 42.6% (46/108) of serum samples from PCV-2-inoculated mice from days 12 to 37. Microscopic lesions consistent with PCV-2 infection were not observed in any mice and PCV-2 DNA and PCV-2 antigen were not detected in tissues by in-situ-hybridization or immunohistochemistry assays, respectively. Based on incidence of PCV-2 DNA in serum samples, the C57BL/6 mouse line was more resistant to PCV-2 infection than the other lines. The results indicate the mouse model likely has limited utility to advance understanding of the pathogenesis of PCV-2 associated lesions, but mice could potentially be important in the epidemiology of PCV-2
Idling Magnetic White Dwarf in the Synchronizing Polar BY Cam. The Noah-2 Project
Results of a multi-color study of the variability of the magnetic cataclysmic
variable BY Cam are presented. The observations were obtained at the Korean
1.8m and Ukrainian 2.6m, 1.2m and 38-cm telescopes in 2003-2005, 56
observational runs cover 189 hours. The variations of the mean brightness in
different colors are correlated with a slope dR/dV=1.29(4), where the number in
brackets denotes the error estimates in the last digits. For individual runs,
this slope is much smaller ranging from 0.98(3) to 1.24(3), with a mean value
of 1.11(1). Near the maximum, the slope becomes smaller for some nights,
indicating more blue spectral energy distribution, whereas the night-to-night
variability has an infrared character. For the simultaneous UBVRI photometry,
the slopes increase with wavelength from dU/dR=0.23(1) to dI/dR=1.18(1). Such
wavelength dependence is opposite to that observed in non-magnetic cataclysmic
variables, in an agreement to the model of cyclotron emission. The principal
component analysis shows two (with a third at the limit of detection)
components of variablitity with different spectral energy distribution, which
possibly correspond to different regions of emission. The scalegram analysis
shows a highest peak corresponding to the 200-min spin variability, its quarter
and to the 30-min and 8-min QPOs. The amplitudes of all these components are
dependent on wavelength and luminosity state. The light curves were fitted by a
statistically optimal trigonometrical polynomial (up to 4-th order) to take
into account a 4-hump structure. The dependences of these parameters on the
phase of the beat period and on mean brightness are discussed. The amplitude of
spin variations increases with an increasing wavelength and with decreasing
brightnessComment: 30pages, 11figures, accepted in Cent.Eur.J.Phy
Domestic Violence and Health Care: Opening PandoraÂżs Box Âż Challenges and Dilemmas
In this article we take a critical stance toward the rational progressive narrative
surrounding the integration of domestic violence within health care. Whilst changes in
recent UK policy and practice have resulted in several tangible benefits, it is argued that
there may be hidden dilemmas and challenges. We suggest that the medical model of care
and its discursive practices position women as individually accountable for domestic
violence-related symptoms and injuries. This may not only be ineffective in terms of
service provision but could also have the potential to reduce the political significance of
domestic violence as an issue of concern for all women. Furthermore, it is argued that the
use of specific metaphors enables practitioners to distance themselves from interactions
that may prove to be less comfortable and provide less than certain outcomes. Our analysis
explores the possibilities for change that might currently be available. This would
appear to involve a consideration of alternative discourses and the reformulation of power
relations and subject positions in health care
Customer emotions in service failure and recovery encounters
Emotions play a significant role in the workplace, and considerable attention has been given to the study of employee emotions. Customers also play a central function in organizations, but much less is known about customer emotions. This chapter reviews the growing literature on customer emotions in employeeâcustomer interfaces with a focus on service failure and recovery encounters, where emotions are heightened. It highlights emerging themes and key findings, addresses the measurement, modeling, and management of customer emotions, and identifies future research streams. Attention is given to emotional contagion, relationships between affective and cognitive processes, customer anger, customer rage, and individual differences
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